› 1v9s

X-ray diffraction
2.1Å resolution

Crystal structure of TT0130 protein from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb1v9s/pdb
PDB entry 1v9s coloured by chain, front view.
PDB entry 1v9s coloured by chain, side view.
PDB entry 1v9s coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Entry authors: Lokanath NK, Kunishima N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180857 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uracil phosphoribosyltransferase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 208 amino acids
Theoretical weight: 23.12 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q72J35 (Residues: 1-208; Coverage: 100%)
Gene names: TT_C0946, upp
Sequence domains: Uracil phosphoribosyltransferase
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
Ligand SO4 23 x SO4
1 modified residue:
Ligand MSE 28 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P3221
Unit cell:
a: 116.151Å b: 116.151Å c: 157.643Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.24 0.238 0.273
Expression system: Escherichia coli BL21(DE3)

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