PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=263-FK-75A)

Interfaces in PDB 3io7 crystal.
Space symmetry group: C 2 2 21. Resolution: 2.60 Å

2-AMINOPYRAZOLO[1,5-A]PYRIMIDINES AS POTENT AND SELECTIVE INHIBITORS OF JAK2

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`95`	`26`	`14748`	`x`	A	-x+1/2,-y+1/2,z-1/2	`6_554`	`95`	`27`	`14748`	`843.4`	`-5.8`	`0.231`	`7`	`4`	`0`	`0.000`
`2`		A	`83`	`26`	`14748`	`◊`	A	x,-y,-z	`4_555`	`83`	`26`	`14748`	`785.0`	`0.3`	`0.623`	`4`	`2`	`0`	`0.000`
`3`		A	`59`	`14`	`14748`	`x`	A	x-1/2,-y+1/2,-z	`8_455`	`62`	`19`	`14748`	`532.7`	`-0.5`	`0.554`	`3`	`2`	`0`	`0.000`
`4`		[1P5]A:1	`29`	`1`	`580`	`◊`	A	x,y,z	`1_555`	`56`	`21`	`14748`	`433.6`	`4.0`	`0.314`	`1`	`0`	`0`	`0.000`
`5`		A	`25`	`10`	`14748`	`◊`	A	-x,y,-z+1/2	`3_555`	`25`	`10`	`14748`	`197.6`	`0.9`	`0.680`	`2`	`0`	`0`	`0.000`
`6`		A	`5`	`1`	`14748`	`◊`	A	-x,y,-z-1/2	`3_554`	`4`	`1`	`14748`	`55.9`	`0.3`	`0.677`	`0`	`0`	`0`	`0.000`
`7`		A	`1`	`1`	`14748`	`f`	[1P5]A:1	-x+1/2,-y+1/2,z-1/2	`6_554`	`3`	`1`	`580`	`10.8`	`0.0`	`0.497`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
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