Searching with a protein structure identifier

By searching for a protein structure identifier with the quick search or by clicking on it in the search results list, you’ll be redirected to the InterPro structure page.

The structure page, like the protein page, is also similar to the sequence search result page, but with extra information, as shown in Figure 23. This contains information on the name of the structure in PDBe, its identifier, its resolution, chains and release date. On the right side, a link to the structure page in the Protein Data Bank in Europe is available.

On the side menu, ‘Entries‘ and ‘Proteins‘ list all the InterPro entries and UniProtKB proteins where the structure is found.

There is also a 3D structure viewer, where you can interact with the structure (e.g. turn, zoom…) and select a member database signature or an InterPro entry to visualise which part of the structure it matches.

For each unique chain in the structure, a protein sequence viewer shows the secondary structure information and the member database signatures matching the chain. Similarly to the protein sequence viewer in other InterPro pages, the member database entry name, the match coordinates (their position on the sequence) and whether the signature is integrated into an InterPro entry is shown at the right hand side of the protein sequence viewer or in the tooltip shown mousing over the coloured bars if it is active.

Links to the InterPro entries matching the sequence can be found both in the tooltip (clicking on the InterPro accession) and in the right hand side of the protein sequence viewer (clicking on the name, short name, and/or accession, depending on the options chosen in the customisation menu). Links to the member database entry InterPro pages can be also found on the right hand side of the protein sequence viewer

Figure 23 InterPro structure page (1y98). The Family and Domain sections of the protein sequence viewer have been expanded by clicking on the black triangle on the left hand side of the title. Click on the icons for more information about different parts of the page.

Note that InterPro-N predictions are not yet available for PDBe chain sequences.