- Course overview
- Search within this course
- Let’s begin the journey
- Travel back in time to the Ice Age: Europe PMC
- Nice moves (genetically speaking): Ensembl
- Travel to high altitude: ArrayExpress
- Future travel (Plants in space): Expression Atlas
- The joys of travel (food) part 1: IntAct
- The joys of travel (food) part 2: ChEMBL
- Travel challenges (jet-lag): Complex Portal
- Perils of travel: PDBe and EMDB
- Travel to a cool destination (The Arctic): MGnify
- Discover more data resources
- The journey continues
- Your feedback
- References
All materials are free cultural works licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, except where further licensing details are provided.
Perils of travel: PDBe and EMDB
Global travel is not just for people. Microbes and pathogens can also travel internationally leading to global health challenges such as Zika virus.
The Zika virus has been linked to microcephaly and other neurological damage in foetuses. It is spreading so rapidly that the World Health Organization has declared it to be an emergency of international concern7. Before 2016, there were no structures of Zika virus protein in the PDBe, however there are now over 100, highlighting the emphasis on research into this disease.
Try solving the following challenge using the Protein Data Bank in Europe (PDBe). Give it a go yourself before looking at the solution at the bottom of this page. Turn the card if you need a hint!
Solution
Explore the following PDBe page to find out how you can solve the above challenge.
About PDBe
The PDBe is a member of the Worldwide Protein Databank (wwPDB), the organisation tasked with the collection, organisation and dissemination of data about biological macromolecular structures. PDBe aims to ‘bring structure to biology’ and provides a comprehensive range of tools and services to make the extensive archive of structural and functional information in the PDBe more accessible to the wider biological community.
Learn more about PDBe in PDBe:Quick tour and watch this webinar to find out how to uncover scientific insights about small molecules in the PDBe using the PDBe-KB Ligand Pages.
Did you know: you can find out more about the polyprotein encoded by the Zika virus’ single stranded RNA genome in UniProt and InterPro.