M-CSA Mechanism and Catalytic Site Atlas

N-sulfoglucosamine sulfohydrolase (M-CSA:951)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of P51688

Reference Sequence	Homologue	Asp31 Asp273 Asp32 Arg282 His181 Arg74 Lys123 Asn274 His125
P51688	P15289	Asp29 Asp281 Asp30 Lys302 His229 Arg73 Lys123 Asn282 His125
P51688	P51691	Asp13 Asp317 Asp14 Lys375 His211 Arg55 Lys113 Asn318 His115
P51688	P33727	Asp55 Asp302 Asp56 Lys320 His244 Arg97 Lys147 Asn303 His149
P51688	P51689	Asp49 Asp356 Asp50 Lys381 His304 Arg93 Lys148 His357 His150
P51688	P15589	Asp34 Asp341 Asp35 Lys367 His289 Arg78 Lys133 His342 His135
P51688	P08842	Asp35 Asp342 Asp36 Lys368 His290 Arg79 Lys134 Gln343 His136
P51688	Q32KH7	Asp56 Asp298 Asp57 Lys316 His240 Arg98 Lys148 Asn299 His150
P51688	Q08DD1	Asp29 Asp281 Asp30 Lys302 His229 Arg73 Lys123 Asn282 His125
P51688	Q5FYA8	Asp15 Asp323 Asp16 Lys348 His271 Arg59 Lys115 Asn324 His117
P51688	Q32KH5	Asp38 Asp288 Asp39 Lys310 His236 Arg82 Lys139 Asn289 His141
P51688	Q5FYB1	Asp55 Asp297 Asp56 Lys315 His239 Arg97 Lys147 Asn298 His149
P51688	P50427	Asp43 Asp350 Asp44 Lys376 His298 Arg87 Lys142 His351 His144
P51688	Q8WNQ7	Asp38 Asp288 Asp39 Lys310 His236 Arg82 Lys139 Asn289 His141
P51688	Q32KJ6	Asp40 Asp290 Asp41 Lys312 His238 Arg84 Lys141 Asn291 His143
P51688	Q32KJ8	Asp55 Asp297 Asp56 Lys315 His239 Arg97 Lys147 Asn298 His149
P51688	P34059	Asp39 Asp288 Asp40 Lys310 His236 Arg83 Lys140 Asn289 His142
P51688	P50428	Asp28 Asp280 Asp29 Lys301 His228 Arg72 Lys122 Asn281 His124
P51688	Q8A2H2	Asp43 Asp332 Asp44 Lys362 His280 Arg87 Lys136 Asn333 His138
P51688	P50430	Asp48 Asp295 Asp49 Lys313 His237 Arg90 Lys140 Asn296 His142
P51688	P51690	Asp46 Asp353 Asp47 Lys378 His301 Arg90 Lys145 His354 His147
P51688	Q32KI9	Asp55 Asp297 Asp56 Lys315 His239 Arg97 Lys147 Asn298 His149
P51688	P50429	Asp54 Asp301 Asp55 Lys319 His243 Arg96 Lys146 Asn302 His148
P51688	Q571E4	Asp36 Asp286 Asp37 Lys308 His234 Arg80 Lys137 Asn287 His139
P51688	P15848	Asp53 Asp300 Asp54 Lys318 His242 Arg95 Lys145 Asn301 His147
P51688	P54793	Asp38 Asp345 Asp39 Lys370 His293 Arg82 Lys137 His346 His139
P51688	P51688	Asp31 Asp273 Asp32 Arg282 His181 Arg74 Lys123 Asn274 His125
P51688	Q89YS5	Asp61 Asp373 Asp62 Lys386 His223 Arg105 Lys149 Gln374 His151
P51688	Q9C0V7	Asp20 Asp327 Asp21 Lys382 His220 Arg62 Lys123 Asn328 His125
P51688	Q8XNV1	Asp11 Asp302 Gln12 Lys315 His210 Arg55 Lys100 His303 His102
P51688	Q08890	Asp47 Asp336 Asp48 Lys349 His231 Arg90 Lys137 His337 His140
P51688	Q08CJ7	Asp35 Asp308 Asp38 Lys321 His203 Arg79 Lys123 His309 His131
P51688	P31447	Asp12 Asp284 Thr13 Lys297 His194 Arg56 Lys100 His285 His102
P51688	P22304	Asp45 Asp334 Asp46 Lys347 His229 Arg88 Lys135 His335 His138
P51688	Q1M964	Asp12 Asp324 Asp17 Lys337 His218 Arg61 Arg113 His325 not aligned
P51688	Q45087	Asp12 Asp324 Asp17 Lys337 His218 Arg61 Arg113 His325 not aligned
P51688	Q0TUK6	Asp11 Asp302 Gln12 Lys315 His210 Arg55 Lys100 His303 His102
P51688	Q60HH5	Asp46 Asp353 Asp47 Lys378 His301 Arg90 Lys145 His354 His147
P51688	Q0IHJ2	Asp42 Asp315 Asp45 Lys328 His210 Arg86 Lys130 His316 His138
P51688	Q9VEX0	Asp62 Asp327 Asp63 Lys341 His236 Arg102 Lys153 His328 not aligned