M-CSA Mechanism and Catalytic Site Atlas

Enoyl-CoA hydratase (M-CSA:461)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of P51659

Reference Sequence	Homologue	Gly533 (main-N) Asp510 His515 Ile530 (main-C)
P51659	P51659	Gly533 Asp510 His515 Ile530
P51659	P97852	Gly532 Asp509 His514 Ile529
P51659	Q12634	not aligned not aligned not aligned not aligned
P51659	P07857	not aligned not aligned not aligned not aligned
P51659	O67610	not aligned not aligned not aligned not aligned
P51659	Q89AG9	not aligned not aligned not aligned not aligned
P51659	P51831	not aligned not aligned not aligned not aligned
P51659	P80869	not aligned not aligned not aligned not aligned
P51659	P33368	not aligned not aligned not aligned not aligned
P51659	Q5HPW0	not aligned not aligned not aligned not aligned
P51659	P73574	not aligned not aligned not aligned not aligned
P51659	Q53217	not aligned not aligned not aligned not aligned
P51659	P0A2C9	not aligned not aligned not aligned not aligned
P51659	P12310	not aligned not aligned not aligned not aligned
P51659	Q9WYG0	not aligned not aligned not aligned not aligned
P51659	Q49117	not aligned not aligned not aligned not aligned
P51659	P33207	not aligned not aligned not aligned not aligned
P51659	Q9X248	not aligned not aligned not aligned not aligned
P51659	Q7FAE1	not aligned not aligned not aligned not aligned
P51659	Q9KQH7	not aligned not aligned not aligned not aligned
P51659	C8WJW0	not aligned not aligned not aligned not aligned
P51659	P0AEK2	not aligned not aligned not aligned not aligned
P51659	Q9FZ42	not aligned not aligned not aligned not aligned
P51659	P9WGR9	not aligned not aligned not aligned not aligned
P51659	Q5FPE5	not aligned not aligned not aligned not aligned
P51659	Q9BTZ2	not aligned not aligned not aligned not aligned
P51659	O07575	not aligned not aligned not aligned not aligned
P51659	Q5RCF8	not aligned not aligned not aligned not aligned
P51659	P87219	not aligned not aligned not aligned not aligned
P51659	Q6MGB5	not aligned not aligned not aligned not aligned
P51659	P0AET8	not aligned not aligned not aligned not aligned
P51659	P50171	not aligned not aligned not aligned not aligned
P51659	A3LZU7	not aligned not aligned not aligned not aligned
P51659	Q68ER2	not aligned not aligned not aligned not aligned
P51659	Q6P0H7	not aligned not aligned not aligned not aligned
P51659	P9WGQ9	not aligned not aligned not aligned not aligned
P51659	Q5TJF5	not aligned not aligned not aligned not aligned
P51659	Q92506	not aligned not aligned not aligned not aligned
P51659	P50941	not aligned not aligned not aligned not aligned
P51659	P38004	not aligned not aligned not aligned not aligned
P51659	Q9MA93	not aligned not aligned not aligned not aligned
P51659	P43713	not aligned not aligned not aligned not aligned
P51659	Q9SCU0	not aligned not aligned not aligned not aligned
P51659	P42317	not aligned not aligned not aligned not aligned
P51659	P55541	not aligned not aligned not aligned not aligned
P51659	P50199	not aligned not aligned not aligned not aligned
P51659	Q9BY49	not aligned not aligned Gly283 not aligned
P51659	O34717	not aligned not aligned not aligned not aligned
P51659	Q9JIF5	not aligned not aligned Gly282 not aligned
P51659	Q9XT00	not aligned not aligned not aligned not aligned
P51659	O34308	not aligned not aligned not aligned not aligned
P51659	Q6CEE9	not aligned not aligned not aligned not aligned
P51659	Q988B7	not aligned not aligned not aligned not aligned
P51659	A4IFA7	not aligned not aligned not aligned not aligned
P51659	Q9URX0	not aligned not aligned not aligned not aligned
P51659	Q91VT4	not aligned not aligned not aligned not aligned
P51659	F4IKM1	not aligned not aligned not aligned not aligned
P51659	Q8N4T8	not aligned not aligned not aligned not aligned
P51659	P50842	not aligned not aligned not aligned not aligned
P51659	P57432	not aligned not aligned not aligned not aligned
P51659	O86034	not aligned not aligned not aligned not aligned
P51659	Q9GKX2	not aligned not aligned not aligned not aligned
P51659	Q45219	not aligned not aligned not aligned not aligned
P51659	P76633	not aligned not aligned not aligned not aligned
P51659	P0A9P9	not aligned not aligned not aligned not aligned
P51659	Q9ZW14	not aligned not aligned not aligned not aligned
P51659	O80713	not aligned not aligned not aligned not aligned
P51659	P46331	not aligned not aligned not aligned not aligned
P51659	C8WGQ3	not aligned not aligned not aligned not aligned
P51659	G5EGA6	not aligned not aligned not aligned not aligned
P51659	Q5RCH8	not aligned not aligned Gly283 not aligned
P51659	D4Z260	not aligned not aligned not aligned not aligned
P51659	Q00791	not aligned not aligned not aligned not aligned
P51659	P39640	not aligned not aligned not aligned not aligned
P51659	P50205	not aligned not aligned not aligned not aligned
P51659	Q9C826	not aligned not aligned not aligned not aligned
P51659	Q8WNV7	not aligned not aligned not aligned not aligned
P51659	Q7TS56	not aligned not aligned not aligned not aligned
P51659	P55575	not aligned not aligned not aligned not aligned
P51659	O54438	not aligned not aligned not aligned not aligned
P51659	Q8SPU8	not aligned not aligned not aligned not aligned
P51659	Q8VID1	not aligned not aligned not aligned not aligned
P51659	E9ET40	not aligned not aligned not aligned not aligned
P51659	O80714	not aligned not aligned not aligned not aligned
P51659	P16544	not aligned not aligned not aligned not aligned
P51659	A0A0B4HVU2	not aligned not aligned not aligned not aligned
P51659	P0A2D1	not aligned not aligned not aligned not aligned
P51659	A0QYC2	not aligned not aligned not aligned not aligned
P51659	P37440	not aligned not aligned not aligned not aligned
P51659	Q9HK58	not aligned not aligned not aligned not aligned
P51659	Q5BH34	not aligned not aligned not aligned not aligned
P51659	Q5HLD8	not aligned not aligned not aligned not aligned
P51659	Q42182	not aligned not aligned not aligned not aligned
P51659	Q94K41	not aligned not aligned not aligned not aligned
P51659	Q99LB2	not aligned not aligned not aligned not aligned
P51659	O18404	not aligned not aligned not aligned not aligned
P51659	Q56840	not aligned not aligned not aligned not aligned
P51659	P06234	not aligned not aligned not aligned not aligned
P51659	P39071	not aligned not aligned not aligned not aligned
P51659	P50161	not aligned not aligned not aligned not aligned
P51659	A9CES4	not aligned not aligned not aligned not aligned
P51659	M1W270	not aligned not aligned not aligned not aligned
P51659	P50160	not aligned not aligned not aligned not aligned
P51659	Q5P5I4	not aligned not aligned not aligned not aligned
P51659	E9EHG1	not aligned not aligned not aligned not aligned
P51659	F4J2Z7	not aligned not aligned not aligned not aligned
P51659	F4J300	not aligned not aligned not aligned not aligned
P51659	Q9SQR4	not aligned not aligned not aligned not aligned
P51659	P07772	not aligned not aligned not aligned not aligned
P51659	Q10216	not aligned not aligned not aligned not aligned
P51659	P9WGT1	not aligned not aligned not aligned not aligned
P51659	Q9ZW15	not aligned not aligned not aligned not aligned
P51659	Q4A054	not aligned not aligned not aligned not aligned
P51659	Q9GME3	not aligned not aligned not aligned not aligned
P51659	Q02207	Gly826 Asp803 His808 Ile823
P51659	Q56318	not aligned not aligned not aligned not aligned
P51659	P71534	not aligned not aligned not aligned not aligned
P51659	P32573	not aligned not aligned not aligned not aligned
P51659	E9QUT3	not aligned not aligned not aligned not aligned
P51659	P73826	not aligned not aligned not aligned not aligned
P51659	Q2FVD5	not aligned not aligned not aligned not aligned
P51659	P37769	not aligned not aligned not aligned not aligned
P51659	Q9SQR2	not aligned not aligned not aligned not aligned
P51659	P45375	not aligned not aligned not aligned not aligned
P51659	Q9Y6Z9	not aligned not aligned not aligned not aligned
P51659	Q9MYP6	not aligned not aligned not aligned not aligned
P51659	Q9X6U2	not aligned not aligned not aligned not aligned
P51659	O02691	not aligned not aligned not aligned not aligned
P51659	D4A1J4	not aligned not aligned not aligned not aligned
P51659	Q4L8Y1	not aligned not aligned not aligned not aligned
P51659	Q9BUT1	not aligned not aligned not aligned not aligned
P51659	Q92RN6	not aligned not aligned not aligned not aligned
P51659	Q05528	not aligned not aligned not aligned not aligned
P51659	P70684	not aligned not aligned not aligned not aligned
P51659	Q8JZV9	not aligned not aligned not aligned not aligned
P51659	P9WGT3	not aligned not aligned not aligned not aligned
P51659	Q3T046	not aligned not aligned not aligned not aligned
P51659	O32229	not aligned not aligned not aligned not aligned
P51659	B6HV34	not aligned not aligned not aligned not aligned
P51659	P15047	not aligned not aligned not aligned not aligned
P51659	Q1NEI6	not aligned not aligned not aligned not aligned
P51659	P87025	not aligned not aligned not aligned not aligned
P51659	P9WGS5	not aligned not aligned not aligned not aligned
P51659	Q73SC8	not aligned not aligned not aligned not aligned
P51659	W3XAA0	not aligned not aligned not aligned not aligned
P51659	A0R518	not aligned not aligned not aligned not aligned
P51659	M2WJF1	not aligned not aligned not aligned not aligned
P51659	O34782	not aligned not aligned not aligned not aligned
P51659	Q561X9	not aligned not aligned not aligned not aligned
P51659	P9WGQ3	not aligned not aligned not aligned not aligned
P51659	Q49WS9	not aligned not aligned not aligned not aligned
P51659	P14697	not aligned not aligned not aligned not aligned
P51659	P14802	not aligned not aligned not aligned not aligned
P51659	Q54XZ0	not aligned not aligned not aligned not aligned
P51659	Q2TBS3	not aligned not aligned not aligned not aligned
P51659	Q01373	Gly826 Asp803 His808 Ile823
P51659	Q9NKW1	not aligned not aligned not aligned not aligned
P51659	P51660	Gly532 Asp509 His514 Ile529
P51659	Q8VYI3	not aligned not aligned not aligned not aligned
P51659	P96825	not aligned not aligned not aligned not aligned
P51659	Q4V8F9	Glu430 Ala415 not aligned Ser426
P51659	A4FUZ6	Asp324 Ala309 not aligned Ser320
P51659	Q9UJQ7	not aligned not aligned not aligned not aligned
P51659	Q2TPA8	Glu396 Ala381 not aligned Ser392
P51659	Q9DAH1	not aligned not aligned not aligned not aligned
P51659	Q5RA68	Asp324 Ala309 not aligned Ser320
P51659	Q6YN16	Asp324 Ala309 not aligned Ser320
P51659	Q66KC4	Glu323 Pro308 not aligned Leu319
P51659	P11915	not aligned not aligned not aligned not aligned
P51659	P9WGS7	not aligned not aligned not aligned not aligned
P51659	Q6P5L8	Glu321 Pro306 not aligned Ile317
P51659	P32020	not aligned not aligned not aligned not aligned
P51659	O62742	not aligned not aligned not aligned not aligned
P51659	P22307	not aligned not aligned not aligned not aligned
P51659	P25145	not aligned not aligned not aligned not aligned
P51659	Q07598	not aligned not aligned not aligned not aligned
P51659	Q8KES3	not aligned not aligned not aligned not aligned
P51659	P40747	not aligned not aligned not aligned not aligned
P51659	Q6GV12	not aligned not aligned not aligned not aligned
P51659	Q2KIJ5	not aligned not aligned not aligned not aligned
P51659	P31808	not aligned not aligned not aligned not aligned
P51659	Q06136	not aligned not aligned not aligned not aligned
P51659	Q0WRJ2	not aligned not aligned not aligned not aligned
P51659	Q7TQA3	not aligned not aligned not aligned not aligned
P51659	Q05A13	not aligned not aligned not aligned not aligned
P51659	A5JYX5	not aligned not aligned not aligned not aligned
P51659	Q8VCH7	not aligned not aligned not aligned not aligned
P51659	Q8N3Y7	not aligned not aligned not aligned not aligned
P51659	Q8HZT6	not aligned not aligned not aligned not aligned
P51659	Q7T2D1	not aligned not aligned not aligned not aligned
P51659	A5PJJ7	not aligned not aligned not aligned not aligned
P51659	Q8IZV5	not aligned not aligned not aligned not aligned
P51659	Q80ZF7	not aligned not aligned not aligned not aligned
P51659	Q7Q732	not aligned not aligned not aligned not aligned
P51659	P37694	not aligned not aligned not aligned not aligned
P51659	F4JZN6	not aligned not aligned not aligned not aligned
P51659	Q5XGF7	not aligned not aligned not aligned not aligned
P51659	Q23655	not aligned not aligned not aligned not aligned
P51659	Q0C898	not aligned not aligned not aligned not aligned
P51659	P0A0H9	not aligned not aligned not aligned not aligned
P51659	P0C0Y5	not aligned not aligned not aligned not aligned
P51659	P19337	not aligned not aligned not aligned not aligned
P51659	P22414	Gly831 Asp808 His813 Ile828
P51659	P39485	not aligned not aligned not aligned not aligned
P51659	P40288	not aligned not aligned not aligned not aligned
P51659	P50162	not aligned not aligned not aligned not aligned
P51659	Q46381	Asp268 not aligned not aligned not aligned
P51659	Q48436	not aligned not aligned not aligned not aligned
P51659	Q9VXJ0	Gly519 Asp496 His501 Ile516
P51659	Q9LBG2	not aligned not aligned not aligned not aligned
P51659	Q93X62	not aligned not aligned not aligned not aligned
P51659	Q94KL8	not aligned not aligned not aligned not aligned
P51659	Q8K9J5	not aligned not aligned not aligned not aligned
P51659	P72332	not aligned not aligned not aligned not aligned
P51659	Q8XBJ4	not aligned not aligned not aligned not aligned
P51659	Q9Z8P2	not aligned not aligned not aligned not aligned
P51659	P17611	not aligned not aligned not aligned not aligned
P51659	P9WGQ8	not aligned not aligned not aligned not aligned
P51659	Q68VY7	not aligned not aligned not aligned not aligned
P51659	P70720	not aligned not aligned not aligned not aligned
P51659	P9WGQ2	not aligned not aligned not aligned not aligned
P51659	Q6GDV6	not aligned not aligned not aligned not aligned
P51659	P39484	not aligned not aligned not aligned not aligned
P51659	Q3KPT7	not aligned not aligned not aligned not aligned
P51659	P55336	not aligned not aligned not aligned not aligned
P51659	P50203	not aligned not aligned not aligned not aligned
P51659	Q6G6J1	not aligned not aligned not aligned not aligned
P51659	Q9RA05	not aligned not aligned not aligned not aligned
P51659	A0A162J3X8	not aligned not aligned not aligned not aligned
P51659	Q8NK50	not aligned not aligned not aligned not aligned
P51659	Q4UK62	not aligned not aligned not aligned not aligned
P51659	Q08632	not aligned not aligned not aligned not aligned
P51659	P9WGS4	not aligned not aligned not aligned not aligned
P51659	Q949M2	not aligned not aligned not aligned not aligned
P51659	Q92EU6	not aligned not aligned not aligned not aligned
P51659	P9WGT0	not aligned not aligned not aligned not aligned
P51659	P23238	not aligned not aligned not aligned not aligned
P51659	O07399	not aligned not aligned not aligned not aligned
P51659	Q937L4	not aligned not aligned not aligned not aligned
P51659	Q2FE21	not aligned not aligned not aligned not aligned
P51659	P0A9Q0	not aligned not aligned not aligned not aligned
P51659	Q8NUV9	not aligned not aligned not aligned not aligned
P51659	Q8GAV9	not aligned not aligned not aligned not aligned
P51659	Q8CN40	not aligned not aligned not aligned not aligned
P51659	Q8KWT4	not aligned not aligned not aligned not aligned
P51659	Q92GE0	not aligned not aligned not aligned not aligned
P51659	Q93X68	not aligned not aligned not aligned not aligned
P51659	Q9PKF7	not aligned not aligned not aligned not aligned
P51659	P39482	not aligned not aligned not aligned not aligned
P51659	P10528	not aligned not aligned not aligned not aligned
P51659	P9WGR8	not aligned not aligned not aligned not aligned
P51659	P99120	not aligned not aligned not aligned not aligned
P51659	P66775	not aligned not aligned not aligned not aligned
P51659	P66782	not aligned not aligned not aligned not aligned
P51659	Q99RF5	not aligned not aligned not aligned not aligned
P51659	P9WGT2	not aligned not aligned not aligned not aligned
P51659	P50204	not aligned not aligned not aligned not aligned
P51659	H9BFQ0	not aligned not aligned not aligned not aligned
P51659	A0A144Y7G4	not aligned not aligned not aligned not aligned
P51659	P41177	not aligned not aligned not aligned not aligned
P51659	P66776	not aligned not aligned not aligned not aligned
P51659	P07999	not aligned not aligned not aligned not aligned
P51659	Q7A3L9	not aligned not aligned not aligned not aligned
P51659	P94681	not aligned not aligned not aligned not aligned
P51659	Q5KTS5	not aligned not aligned not aligned not aligned
P51659	P69166	not aligned not aligned not aligned not aligned
P51659	P0A5Y5	not aligned not aligned not aligned not aligned
P51659	P0AEK3	not aligned not aligned not aligned not aligned
P51659	Q5HJP2	not aligned not aligned not aligned not aligned
P51659	P0AET9	not aligned not aligned not aligned not aligned
P51659	Q949M3	not aligned not aligned not aligned not aligned
P51659	P0A0I0	not aligned not aligned not aligned not aligned
P51659	P28643	not aligned not aligned not aligned not aligned
P51659	Q1RKB7	not aligned not aligned not aligned not aligned
P51659	Q5HGK2	not aligned not aligned not aligned not aligned
P51659	P06235	not aligned not aligned not aligned not aligned
P51659	H9BFQ1	not aligned not aligned not aligned not aligned
P51659	Q94KL7	not aligned not aligned not aligned not aligned
P51659	Q04520	not aligned not aligned not aligned not aligned
P51659	P0A2D2	not aligned not aligned not aligned not aligned
P51659	Q6NUE2	not aligned not aligned not aligned not aligned
P51659	F1SWA0	not aligned not aligned not aligned not aligned
P51659	P99093	not aligned not aligned not aligned not aligned
P51659	Q93X67	not aligned not aligned not aligned not aligned
P51659	P0A2D0	not aligned not aligned not aligned not aligned
P51659	C1C4R8	not aligned not aligned not aligned not aligned
P51659	P39483	not aligned not aligned not aligned not aligned
P51659	Q9L9F8	not aligned not aligned not aligned not aligned
P51659	P0C0Y4	not aligned not aligned not aligned not aligned
P51659	P27582	not aligned not aligned not aligned not aligned
P51659	P07914	not aligned not aligned not aligned not aligned
P51659	B8H1Z0	not aligned not aligned not aligned not aligned
P51659	P0DOV5	not aligned not aligned not aligned not aligned
P51659	P9WGS6	not aligned not aligned not aligned not aligned
P51659	A0A097ZPC9	not aligned not aligned not aligned not aligned
P51659	Q92EK7	not aligned not aligned not aligned not aligned
P51659	Q6PAY8	Glu323 Pro308 not aligned Ser319
P51659	Q8TFD5	not aligned not aligned not aligned not aligned
P51659	Q6GHK4	not aligned not aligned not aligned not aligned
P51659	Q5HD73	not aligned not aligned not aligned not aligned
P51659	Q6GKH9	not aligned not aligned not aligned not aligned
P51659	A7AZH2	not aligned not aligned not aligned not aligned
P51659	Q6G9Y2	not aligned not aligned not aligned not aligned
P51659	Q8CPI3	not aligned not aligned not aligned not aligned
P51659	Q6GCZ8	not aligned not aligned not aligned not aligned
P51659	A7B3K3	not aligned not aligned not aligned not aligned
P51659	B2KWH7	not aligned not aligned not aligned not aligned
P51659	A0A1L5BU05	not aligned not aligned not aligned not aligned
P51659	A0A0B4GT47	not aligned not aligned not aligned not aligned
P51659	A0A0B4FP77	not aligned not aligned not aligned not aligned
P51659	A0A0B4GU97	not aligned not aligned not aligned not aligned
P51659	P0CU75	not aligned not aligned not aligned not aligned
P51659	B0ZT44	not aligned not aligned not aligned not aligned