M-CSA Mechanism and Catalytic Site Atlas

Lysine 2,3-aminomutase (M-CSA:358)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of Q9XBQ8

Reference Sequence	Homologue	Arg112 (main-N) Tyr113 (main-N) Arg116 (main-C) Cys132 Arg134 Lys337 Asp293 Asp330 Cys129 Cys125
Q9XBQ8	Q9XBQ8	Arg112 Tyr113 Arg116 Cys132 Arg134 Lys337 Asp293 Asp330 Cys129 Cys125
Q9XBQ8	Q6LYX4	Arg123 Tyr124 Arg127 Cys143 Arg145 Lys348 Asp304 Asp341 Cys140 Cys136
Q9XBQ8	E3PRJ8	Arg111 Tyr112 Arg115 Cys131 Arg133 Lys336 Asp292 Asp329 Cys128 Cys124
Q9XBQ8	O67554	Lys87 Tyr88 Thr91 Cys107 Arg109 Lys317 Arg274 Ser312 Cys104 Cys100
Q9XBQ8	O34676	Arg121 Tyr122 Arg125 Cys141 Arg143 Lys346 Asp302 Asp339 Cys138 Cys134
Q9XBQ8	P44641	Lys108 Tyr109 Arg112 Cys128 Arg130 Lys333 Asp289 Glu326 Cys125 Cys121
Q9XBQ8	Q8RHX4	Arg114 Tyr115 Arg118 Cys134 Arg136 Lys339 Asp295 Asp332 Cys131 Cys127
Q9XBQ8	O66761	Arg108 Tyr109 Arg112 Cys128 Arg130 Lys334 Asp290 Asp327 Cys125 Cys121
Q9XBQ8	Q185C5	Arg151 Tyr152 Arg155 Cys171 Arg173 Lys376 Lys332 Asn369 Cys168 Cys164
Q9XBQ8	Q58051	Arg325 Tyr326 Ile329 Cys345 Arg347 Lys552 Lys508 Asn546 Cys342 Cys338
Q9XBQ8	P39280	Lys107 Tyr108 Arg111 Cys127 Arg129 Lys332 Asp288 Glu325 Cys124 Cys120
Q9XBQ8	Q8PYC9	Arg113 Tyr114 Arg117 Cys133 Arg135 Lys338 Asp294 Asp331 Cys130 Cys126
Q9XBQ8	Q8ZKB8	Lys107 Tyr108 Arg111 Cys127 Arg129 Lys332 Asp288 Glu325 Cys124 Cys120
Q9XBQ8	Q89B32	Lys107 Tyr108 Arg111 Cys127 Arg129 Lys332 Asp288 Glu325 Cys124 Cys120
Q9XBQ8	O83158	Gln95 Tyr96 Arg99 Cys115 Arg117 Lys320 Asp276 Asp313 Cys112 Cys108
Q9XBQ8	Q44634	Lys108 Tyr109 Arg112 Cys128 Arg130 Lys333 Asp289 Asp326 Cys125 Cys121