Pyruvate dehydrogenase (cytochrome) (M-CSA:275)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of P07003

Reference Sequence Homologue Gln113 Val380 Phe465 Glu50 Phe112
P07003
FunTreePfam
P20906
FunTreePfam
Leu110 Ser376 Ala460 Glu47 Leu109
P07003
FunTreePfam
P37063
FunTreePfam
Gln122 Val394 Phe479 Glu59 Phe121
P07003
FunTreePfam
P07003
FunTreePfam
Gln113 Val380 Phe465 Glu50 Phe112
P07003
FunTreePfam
P07342
FunTreePfam
Gln202 Val497 Met582 Glu139 Phe201
P07003
FunTreePfam
P0AEP7
FunTreePfam
Gln115 Ile393 Leu478 Val51 Phe114
P07003
FunTreePfam
Q9LCV9
FunTreePfam
Gln121 Ile410 Leu495 Glu57 His120
P07003
FunTreePfam
P27696
FunTreePfam
Gln120 Met394 Met479 Glu57 His119
P07003
FunTreePfam
P37251
FunTreePfam
Gln127 Val401 Met486 Glu64 Phe126
P07003
FunTreePfam
Q9UJ83
FunTreePfam
Gln123 Gly398 Phe489 Glu60 Phe122
P07003
FunTreePfam
P96591
FunTreePfam
Gln115 Val382 Met467 Glu52 Phe114
P07003
FunTreePfam
P06672
FunTreePfam
His122 Thr388 Ile472 Glu50 Tyr121
P07003
FunTreePfam
Q57725
FunTreePfam
Gln110 Val394 Met479 Glu47 Phe109
P07003
FunTreePfam
O06335
FunTreePfam
Gln110 Val392 Pro481 Glu48 Gln109
P07003
FunTreePfam
Q02137
FunTreePfam
Gln120 Val393 Met478 Glu57 Phe119
P07003
FunTreePfam
Q9P7P6
FunTreePfam
Ser133 Thr398 Ile482 Glu61 Phe132
P07003
FunTreePfam
P9WG37
FunTreePfam
Glu133 Gln394 Val478 Glu61 Phe132
P07003
FunTreePfam
Q9QXE0
FunTreePfam
Gln126 Gly401 Phe492 Glu63 Phe125
P07003
FunTreePfam
P33287
FunTreePfam
Thr128 Thr392 Ile476 Glu56 Tyr127
P07003
FunTreePfam
Q9CBD6
FunTreePfam
Glu129 Gln390 Ile474 Glu57 Phe128
P07003
FunTreePfam
Q92345
FunTreePfam
Glu128 Thr394 Ile478 Glu56 Phe127
P07003
FunTreePfam
P17597
FunTreePfam
Gln207 Val485 Met570 Glu144 Phe206
P07003
FunTreePfam
P09114
FunTreePfam
Gln201 Val479 Met564 Glu138 Phe200
P07003
FunTreePfam
P40811
FunTreePfam
Gln114 Val395 Met480 Glu51 Phe113
P07003
FunTreePfam
P9WG41
FunTreePfam
Gln148 Val427 Met512 Glu85 Phe147
P07003
FunTreePfam
P45261
FunTreePfam
Gln114 Val394 Met479 Glu51 Phe113
P07003
FunTreePfam
Q89AP7
FunTreePfam
Gln114 Val395 Met480 Glu51 Phe113
P07003
FunTreePfam
Q9LF46
FunTreePfam
Gln121 Gly404 not aligned Glu58 Phe120
P07003
FunTreePfam
P57321
FunTreePfam
Gln114 Val392 Met477 Glu51 Phe113
P07003
FunTreePfam
Q7U5G1
FunTreePfam
Gln134 Val411 Met495 Glu71 Phe133
P07003
FunTreePfam
Q54DA9
FunTreePfam
Gln110 Gly410 Leu497 Glu47 Phe109
P07003
FunTreePfam
P39994
FunTreePfam
Gln112 Gly393 not aligned Glu49 Phe111
P07003
FunTreePfam
P36620
FunTreePfam
Gln197 Val495 Met580 Glu134 Phe196
P07003
FunTreePfam
Q7XKQ8
FunTreePfam
Gln195 Val476 Met561 Glu132 Phe194
P07003
FunTreePfam
O33112
FunTreePfam
Gln155 Val434 Met519 Glu92 Phe154
P07003
FunTreePfam
Q41768
FunTreePfam
Gln175 Val453 Met538 Glu112 Phe174
P07003
FunTreePfam
P00893
FunTreePfam
Gln114 Val395 Met480 Glu51 Phe113
P07003
FunTreePfam
P42463
FunTreePfam
Gln136 Val414 Met499 Glu73 Phe135
P07003
FunTreePfam
Q8CHM7
FunTreePfam
Gln126 Gly401 Phe492 Glu63 Phe125
P07003
FunTreePfam
P08142
FunTreePfam
Gln123 Val391 Leu476 Glu60 Phe122
P07003
FunTreePfam
Q5KPJ5
FunTreePfam
Gln236 Val539 Met624 Glu173 Phe235
P07003
FunTreePfam
Q6K2E8
FunTreePfam
Gln181 Val459 Met544 Glu118 Phe180
P07003
FunTreePfam
Q898E8
FunTreePfam
Gln130 Ser440 Cys525 Glu65 Leu129
P07003
FunTreePfam
Q04789
FunTreePfam
Gln123 Ile397 Met482 Glu60 His122
P07003
FunTreePfam
Q8Y9Y1
FunTreePfam
Gln132 Ala440 Cys526 Glu67 Leu131
P07003
FunTreePfam
Q0JMH0
FunTreePfam
Gln122 Gly409 not aligned Glu59 Phe121
P07003
FunTreePfam
D5AKX8
FunTreePfam
Gln112 Ile405 not aligned Glu49 Phe111
P07003
FunTreePfam
P0AFI0
FunTreePfam
Glu119 Gly395 not aligned Glu54 Tyr118
P07003
FunTreePfam
Q81QB5
FunTreePfam
Gln130 Ala440 Cys525 Glu65 Leu129
P07003
FunTreePfam
Q58077
FunTreePfam
Gln113 Ala346 not aligned Glu50 Phe112
P07003
FunTreePfam
A3SR25
FunTreePfam
Gln124 Ile417 not aligned Glu61 Phe123
P07003
FunTreePfam
Q9Y7M1
FunTreePfam
Gln112 Gly394 Leu481 Glu49 Phe111
P07003
FunTreePfam
Q9HUR2
FunTreePfam
Leu110 Ser376 Ala460 Glu47 Met109
P07003
FunTreePfam
P9WG39
FunTreePfam
Gln120 Ala386 Leu471 Glu57 Leu119
P07003
FunTreePfam
Q41769
FunTreePfam
Gln175 Val453 Met538 Glu112 Phe174
P07003
FunTreePfam
Q5KYR0
FunTreePfam
Gln130 Ala440 Cys525 Glu65 Leu129
P07003
FunTreePfam
P09342
FunTreePfam
Gln204 Val482 Met567 Glu141 Phe203
P07003
FunTreePfam
Q65D03
FunTreePfam
Gln131 Ala440 Cys525 Glu66 Leu130
P07003
FunTreePfam
Q9HUI8
FunTreePfam
His141 Met407 Gln493 Glu76 Leu140
P07003
FunTreePfam
P42415
FunTreePfam
Gln131 Ala440 Cys525 Glu66 Leu130
P07003
FunTreePfam
Q5WKY8
FunTreePfam
Gln131 Ser440 Cys525 Glu66 Leu130
P07003
FunTreePfam
Q6NV04
FunTreePfam
Gln150 Gly457 Gln542 Glu87 Leu149
P07003
FunTreePfam
Q92UW6
FunTreePfam
Gln112 Ile405 not aligned Glu49 Phe111
P07003
FunTreePfam
A6QQT9
FunTreePfam
Gln161 Gly468 Gln553 Glu98 Leu160
P07003
FunTreePfam
O61856
FunTreePfam
Gln165 Gly475 Gln560 Glu102 Leu164
P07003
FunTreePfam
Q9KAG9
FunTreePfam
Gln130 Ala439 Cys524 Glu65 Leu129
P07003
FunTreePfam
A1L0T0
FunTreePfam
Gln161 Gly468 Gln553 Glu98 Leu160
P07003
FunTreePfam
B2TJ86
FunTreePfam
Gln130 Ser439 Cys524 Glu65 Leu129
P07003
FunTreePfam
Q8XP76
FunTreePfam
Gln127 Ala436 Cys521 Glu62 Leu126
P07003
FunTreePfam
Q8BU33
FunTreePfam
Gln161 Gly468 Gln553 Glu98 Leu160
P07003
FunTreePfam
P0CH62
FunTreePfam
Ser104 Ile398 Ala483 Glu52 Asn103
P07003
FunTreePfam
P40149
FunTreePfam
Glu121 Gly400 not aligned Glu56 Tyr120
P07003
FunTreePfam
P51852
FunTreePfam
Asp119 Met380 Met461 Glu48 Leu118
P07003
FunTreePfam
P69684
FunTreePfam
Gln124 Val403 Met487 Glu61 Phe123
P07003
FunTreePfam
Q92EQ4
FunTreePfam
Gln132 Ala440 Cys526 Glu67 Leu131
P07003
FunTreePfam
A5U0P1
FunTreePfam
Glu133 Gln394 Val478 Glu61 Phe132
P07003
FunTreePfam
P0DP89
FunTreePfam
Gln110 not aligned not aligned Glu47 Phe109
P07003
FunTreePfam
A0PL16
FunTreePfam
Glu133 Gln394 Val478 Glu61 Phe132
P07003
FunTreePfam
Q63B73
FunTreePfam
Gln130 Ala440 Cys525 Glu65 Leu129
P07003
FunTreePfam
Q84H41
FunTreePfam
Gln125 Ile424 not aligned Glu62 Phe124
P07003
FunTreePfam
P66947
FunTreePfam
Gln120 Ala386 Leu471 Glu57 Leu119
P07003
FunTreePfam
P51853
FunTreePfam
Gln113 Gly393 Ala480 Glu50 Leu112
P07003
FunTreePfam
Q84H44
FunTreePfam
Gln124 Ile419 not aligned Glu61 Phe123
P07003
FunTreePfam
P0A623
FunTreePfam
Gln148 Val427 Met512 Glu85 Phe147
P07003
FunTreePfam
Q04524
FunTreePfam
Gln120 Met394 Met479 Glu57 His119
P07003
FunTreePfam
Q6HIK2
FunTreePfam
Gln130 Ala440 Cys525 Glu65 Leu129
P07003
FunTreePfam
C3PAZ3
FunTreePfam
Gln130 Ala440 Cys525 Glu65 Leu129
P07003
FunTreePfam
P0DP90
FunTreePfam
Gln110 Val375 Met460 Glu47 Phe109
P07003
FunTreePfam
P0AFI1
FunTreePfam
Glu119 Gly395 not aligned Glu54 Tyr118
P07003
FunTreePfam
Q4V1F5
FunTreePfam
Gln130 Ala440 Cys525 Glu65 Leu129
P07003
FunTreePfam
B2V4K0
FunTreePfam
Gln130 Ser439 Cys524 Glu65 Leu129
P07003
FunTreePfam
Q0TUZ2
FunTreePfam
Gln127 Ala436 Cys521 Glu62 Leu126
P07003
FunTreePfam
O19929
FunTreePfam
Gln123 Val405 Met489 Glu60 Phe122
P07003
FunTreePfam
P27819
FunTreePfam
Gln189 Val467 Met552 Glu126 Phe188
P07003
FunTreePfam
A7ZAH8
FunTreePfam
Gln131 Ala440 Cys525 Glu66 Leu130
P07003
FunTreePfam
P9WG38
FunTreePfam
Gln120 Ala386 Leu471 Glu57 Leu119
P07003
FunTreePfam
Q59498
FunTreePfam
Gln152 Val430 Met515 Glu89 Phe151
P07003
FunTreePfam
O08353
FunTreePfam
Gln110 Val402 Met487 Glu47 Phe109
P07003
FunTreePfam
Q1XDF6
FunTreePfam
Gln124 Val403 Met487 Glu61 Phe123
P07003
FunTreePfam
Q723S8
FunTreePfam
Gln132 Ala440 Cys526 Glu67 Leu131
P07003
FunTreePfam
O78518
FunTreePfam
Gln123 Val402 Met486 Glu60 Phe122
P07003
FunTreePfam
P69683
FunTreePfam
Gln124 Val403 Met487 Glu61 Phe123
P07003
FunTreePfam
P27818
FunTreePfam
Gln192 Val470 Met555 Glu129 Phe191
P07003
FunTreePfam
O85293
FunTreePfam
Gln114 Val392 Met477 Glu51 Phe113
P07003
FunTreePfam
A0REB6
FunTreePfam
Gln130 Ala440 Cys525 Glu65 Leu129
P07003
FunTreePfam
A5YBJ6
FunTreePfam
Gln136 Ala444 Ser529 Glu71 Leu135
P07003
FunTreePfam
B7JPM3
FunTreePfam
Gln130 Ala440 Cys525 Glu65 Leu129
P07003
FunTreePfam
Q6SSJ3
FunTreePfam
Gln236 Val539 Met624 Glu173 Phe235
P07003
FunTreePfam
P9WG40
FunTreePfam
Gln148 Val427 Met512 Glu85 Phe147
P07003
FunTreePfam
Q93PS3
FunTreePfam
Gln115 Ile397 not aligned Glu52 Phe114
P07003
FunTreePfam
P9WG36
FunTreePfam
Glu133 Gln394 Val478 Glu61 Phe132
P07003
FunTreePfam
C1EVJ3
FunTreePfam
Gln130 Ala440 Cys525 Glu65 Leu129
P07003
FunTreePfam
Q7U140
FunTreePfam
Glu133 Gln394 Val478 Glu61 Phe132
P07003
FunTreePfam
A4IPB6
FunTreePfam
Gln130 Ser435 Cys520 Glu65 Leu129
P07003
FunTreePfam
P0AEP8
FunTreePfam
Gln115 Ile393 Leu478 Val51 Phe114
P07003
FunTreePfam
P27868
FunTreePfam
Gln124 Val406 Met490 Glu61 Phe123
P07003
FunTreePfam
Q9RQ65
FunTreePfam
Gln114 Val395 Met480 Glu51 Phe113
P07003
FunTreePfam
P14874
FunTreePfam
Gln183 Val460 Met545 Glu120 Phe182
P07003
FunTreePfam
Q54970
FunTreePfam
Gln116 Val388 Phe473 Glu53 Phe115
P07003
FunTreePfam
P10343
FunTreePfam
Gln114 not aligned not aligned Glu51 Phe113
P07003
FunTreePfam
C3LHY1
FunTreePfam
Gln130 Ala440 Cys525 Glu65 Leu129
P07003
FunTreePfam
A1KGY5
FunTreePfam
Glu133 Gln394 Val478 Glu61 Phe132