M-CSA Mechanism and Catalytic Site Atlas

Benzoylformate decarboxylase (M-CSA:220)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of P20906

Reference Sequence	Homologue	Gly25 (main-N) His70 Glu47 Glu28 Ser26 His281 Gly401 (main-C)
P20906	P06169	Gly27 Thr73 Glu51 Asn30 Asp28 not aligned Gly413
P20906	P20906	Gly25 His70 Glu47 Glu28 Ser26 His281 Gly401
P20906	P37063	Gly34 Ser82 Glu59 Ile37 Gly35 not aligned Ala420
P20906	P07003	Gly26 Ser73 Glu50 Leu29 Asp27 not aligned Gly406
P20906	P07342	Gly115 Thr162 Glu139 Ile118 Gly116 not aligned Gly523
P20906	P0AEP7	Gly27 Thr75 Val51 Ile30 Ala28 not aligned Gly419
P20906	Q9LCV9	Gly35 Thr80 Glu57 Ala38 Arg36 not aligned Ser436
P20906	P27696	Gly34 Thr80 Glu57 Ile37 Ala35 not aligned Gln420
P20906	P37251	Gly41 Thr87 Glu64 Val44 Gly42 not aligned Gly427
P20906	Q9UJ83	Gly37 Val83 Glu60 Val40 Ile38 not aligned Gly424
P20906	P96591	Gly27 Ile75 Glu52 Ile30 Asp28 not aligned Ala408
P20906	Q57725	Gly24 Thr70 Glu47 Met27 Gly25 not aligned Gly420
P20906	A2Y5L9	Gly66 Thr112 Glu90 Asn69 Asp67 not aligned Gly455
P20906	O06335	Thr24 Val70 Glu48 Leu27 Ser25 not aligned Ser418
P20906	A0R480	Gly29 Thr75 Glu53 Gln32 Asp30 not aligned Ala411
P20906	P87208	Gly36 Thr81 Glu59 Asn39 Asp37 not aligned Gly420
P20906	Q9M039	Gly53 Thr99 Glu77 Asn56 Asp54 not aligned Gly442
P20906	Q02137	Gly33 Thr80 Glu57 Met36 Gly34 not aligned Gly419
P20906	Q9P7P6	Gly37 Thr83 Glu61 Asn40 Asp38 not aligned Gly423
P20906	Q9FFT4	Gly68 Thr114 Glu92 Asn71 Asp69 not aligned Gly457
P20906	P9WG37	Gly37 Thr83 Glu61 Asn40 Asp38 not aligned Gly419
P20906	P83779	Gly27 Thr75 Glu51 Asn30 Asp28 not aligned Gly416
P20906	Q9QXE0	Gly40 Val86 Glu63 Val43 Ile41 not aligned Gly427
P20906	Q12629	Gly27 Thr73 Glu51 Asn30 Asp28 not aligned Gly413
P20906	Q9M040	Gly64 Thr110 Glu88 Asn67 Asp65 not aligned Gly453
P20906	Q742Q2	Gly35 Thr81 Glu59 Asn38 Asp36 not aligned Gly417
P20906	Q6FJA3	Gly27 Thr73 Glu51 Asn30 Asp28 not aligned Gly413
P20906	P26263	Gly27 Thr73 Glu51 Asn30 Asp28 not aligned Gly413
P20906	O82647	Gly68 Thr114 Glu92 Asn71 Asp69 not aligned Gly457
P20906	Q92345	Gly32 Thr78 Glu56 Asn35 Asp33 not aligned Gly419
P20906	P51845	not aligned Thr17 not aligned not aligned not aligned not aligned Gly360
P20906	P17597	Gly120 Thr167 Glu144 Ser123 Gly121 not aligned Gly511
P20906	P09114	Gly114 Thr161 Glu138 Ser117 Gly115 not aligned Gly505
P20906	P40811	Gly27 Thr74 Glu51 Val30 Gly28 not aligned Gly421
P20906	P9WG41	Gly61 Thr108 Glu85 Val64 Gly62 not aligned Gly453
P20906	P45261	Gly27 Thr74 Glu51 Val30 Gly28 not aligned Gly420
P20906	Q89AP7	Gly27 Thr74 Glu51 Val30 Gly28 not aligned Gly421
P20906	Q9LF46	Gly35 Val81 Glu58 Val38 Ile36 not aligned Gly430
P20906	P57321	Gly27 Thr74 Glu51 Val30 Gly28 not aligned Gly418
P20906	Q7U5G1	Gly44 Thr94 Glu71 Ile47 Gly45 not aligned Gly436
P20906	Q54DA9	Gly24 Val70 Glu47 Ile27 Val25 not aligned Ala436
P20906	P36620	Gly110 Thr157 Glu134 Ile113 Gly111 not aligned Gly521
P20906	Q7XKQ8	Gly108 Thr155 Glu132 Ser111 Gly109 not aligned Gly502
P20906	O33112	Gly68 Thr115 Glu92 Val71 Gly69 not aligned Gly460
P20906	Q41768	Gly88 Thr135 Glu112 Ser91 Gly89 not aligned Gly479
P20906	P00893	Gly27 Thr74 Glu51 Val30 Gly28 not aligned Gly421
P20906	P42463	Gly49 Thr96 Glu73 Val52 Gly50 not aligned Gly440
P20906	Q8CHM7	Gly40 Val86 Glu63 Val43 Ile41 not aligned Gly427
P20906	P08142	Gly36 Cys83 Glu60 Ile39 Gly37 not aligned Gly417
P20906	Q5KPJ5	Gly149 Thr196 Glu173 Ile152 Gly150 not aligned Gly565
P20906	Q6K2E8	Gly94 Thr141 Glu118 Ser97 Gly95 not aligned Gly485
P20906	Q04789	Gly37 Thr83 Glu60 Ile40 Ala38 not aligned Gln423
P20906	Q0JMH0	Gly36 Val82 Glu59 Val39 Ile37 not aligned Gly435
P20906	D5AKX8	Gly26 Gln72 Glu49 Phe29 Ser27 not aligned Gly431
P20906	P0AFI0	Gly31 Val77 Glu54 Val34 Ile32 not aligned Gly421
P20906	Q81QB5	Gly39 Ser90 Glu65 Asn42 His40 not aligned Ser466
P20906	A3SR25	Gly38 Gln84 Glu61 Met41 Ser39 not aligned Gly443
P20906	Q9HUR2	Gly25 His70 Glu47 Glu28 Ser26 His281 Gly401
P20906	P9WG39	Gly34 Thr80 Glu57 Leu37 Gly35 not aligned Gly412
P20906	Q41769	Gly88 Thr135 Glu112 Ser91 Gly89 not aligned Gly479
P20906	Q5KYR0	Gly39 Ser90 Glu65 Asn42 His40 not aligned Ser466
P20906	P09342	Gly117 Thr164 Glu141 Ser120 Gly118 not aligned Gly508
P20906	Q65D03	Gly40 Ser91 Glu66 Asn43 His41 not aligned Ser466
P20906	Q9HUI8	Gly53 Ile99 Glu76 Thr56 Val54 not aligned Gly433
P20906	P42415	Gly40 Ser91 Glu66 Asn43 His41 not aligned Ser466
P20906	Q5WKY8	Gly40 Ser91 Glu66 Asn43 His41 not aligned Ser466
P20906	O53554	Gly24 His71 Glu48 Glu27 Thr25 Pro278 Gly380
P20906	Q6NV04	Gly64 Thr110 Glu87 Ile67 Gly65 not aligned Gly483
P20906	Q92UW6	Gly26 Gln72 Glu49 Met29 Ser27 not aligned Gly431
P20906	A6QQT9	Gly75 Thr121 Glu98 Ile78 Gly76 not aligned Gly494
P20906	A5FG67	Gly29 Thr76 Glu53 Asn32 Ser30 not aligned Gly418
P20906	A1L0T0	Gly75 Thr121 Glu98 Ile78 Gly76 not aligned Gly494
P20906	Q8XP76	Gly36 Ser87 Glu62 Ile39 His37 not aligned Ser462
P20906	Q8BU33	Gly75 Thr121 Glu98 Ile78 Gly76 not aligned Gly494
P20906	P0CH62	Gly27 Ala74 Glu52 Ser30 His28 not aligned Gly424
P20906	P40149	Gly33 Val79 Glu56 Ile36 Ile34 not aligned Gly426
P20906	P51852	Gly24 Thr71 Glu48 Ala27 Asp25 not aligned Ala402
P20906	P69684	Gly34 Thr84 Glu61 Ile37 Gly35 not aligned Gly428
P20906	A5U0P1	Gly37 Thr83 Glu61 Asn40 Asp38 not aligned Gly419
P20906	P0DP89	Gly24 Thr70 Glu47 Ile27 Gly25 not aligned not aligned
P20906	A0PL16	Gly37 Thr83 Glu61 Asn40 Asp38 not aligned Gly419
P20906	Q63B73	Gly39 Ser90 Glu65 Asn42 His40 not aligned Ser466
P20906	Q84H41	Gly39 Gln85 Glu62 Phe42 Ser40 not aligned Gly450
P20906	P66947	Gly34 Thr80 Glu57 Leu37 Gly35 not aligned Gly412
P20906	P51853	Gly27 not aligned Glu50 Ile30 Ala28 not aligned Gly419
P20906	P51851	not aligned not aligned not aligned not aligned not aligned not aligned Gly255
P20906	Q84H44	Gly38 Gln84 Glu61 Phe41 Ser39 not aligned Gly445
P20906	P0A623	Gly61 Thr108 Glu85 Val64 Gly62 not aligned Gly453
P20906	A0QBE6	Gly35 Thr81 Glu59 Asn38 Asp36 not aligned Gly417
P20906	Q04524	Gly34 Thr80 Glu57 Ile37 Ala35 not aligned Gln420
P20906	Q6HIK2	Gly39 Ser90 Glu65 Asn42 His40 not aligned Ser466
P20906	C3PAZ3	Gly39 Ser90 Glu65 Asn42 His40 not aligned Ser466
P20906	P0DP90	Gly24 Thr70 Glu47 Ile27 Gly25 not aligned Gly401
P20906	P33149	Gly27 Thr73 Glu51 Asn30 Asp28 not aligned Gly413
P20906	P0AFI1	Gly31 Val77 Glu54 Val34 Ile32 not aligned Gly421
P20906	Q4V1F5	Gly39 Ser90 Glu65 Asn42 His40 not aligned Ser466
P20906	Q0TUZ2	Gly36 Ser87 Glu62 Ile39 His37 not aligned Ser462
P20906	P34734	Gly27 Thr73 Glu51 Asn30 Asp28 not aligned Gly413
P20906	O19929	Gly33 Thr83 Glu60 Ile36 Gly34 not aligned Gly430
P20906	P27819	Gly102 Thr149 Glu126 Ser105 Gly103 not aligned Gly493
P20906	P16467	Gly27 Thr73 Glu51 Asn30 Asp28 not aligned Gly413
P20906	A7ZAH8	Gly40 Ser91 Glu66 Asn43 His41 not aligned Ser466
P20906	P9WG38	Gly34 Thr80 Glu57 Leu37 Gly35 not aligned Gly412
P20906	Q59498	Gly65 Thr112 Glu89 Val68 Gly66 not aligned Gly456
P20906	O08353	Gly24 Thr70 Glu47 Leu27 Gly25 not aligned Gly428
P20906	Q1XDF6	Gly34 Thr84 Glu61 Ile37 Gly35 not aligned Gly428
P20906	O78518	Gly33 Thr83 Glu60 Ile36 Gly34 not aligned Gly427
P20906	P69683	Gly34 Thr84 Glu61 Ile37 Gly35 not aligned Gly428
P20906	P27818	Gly105 Thr152 Glu129 Ser108 Gly106 not aligned Gly496
P20906	O85293	Gly27 Thr74 Glu51 Val30 Gly28 not aligned Gly418
P20906	A0REB6	Gly39 Ser90 Glu65 Asn42 His40 not aligned Ser466
P20906	A5YBJ6	Gly45 Ser96 Glu71 Asn48 His46 not aligned Ser470
P20906	B7JPM3	Gly39 Ser90 Glu65 Asn42 His40 not aligned Ser466
P20906	Q6SSJ3	Gly149 Thr196 Glu173 Ile152 Gly150 not aligned Gly565
P20906	P9WG40	Gly61 Thr108 Glu85 Val64 Gly62 not aligned Gly453
P20906	Q93PS3	Gly29 Gln75 Glu52 Phe32 Ser30 not aligned Gly423
P20906	P9WG36	Gly37 Thr83 Glu61 Asn40 Asp38 not aligned Gly419
P20906	C1EVJ3	Gly39 Ser90 Glu65 Asn42 His40 not aligned Ser466
P20906	Q7U140	Gly37 Thr83 Glu61 Asn40 Asp38 not aligned Gly419
P20906	P0AEP8	Gly27 Thr75 Val51 Ile30 Ala28 not aligned Gly419
P20906	P27868	Gly34 Thr84 Glu61 Asn37 Gly35 not aligned Gly431
P20906	Q9RQ65	Gly27 Thr74 Glu51 Val30 Gly28 not aligned Gly421
P20906	P14874	Gly96 Thr143 Glu120 Ser99 Gly97 not aligned Gly486
P20906	Q54970	Ser29 Ser76 Glu53 Leu32 Gly30 not aligned Ala414
P20906	Q6DDK5	Gly61 Thr107 Glu84 Ile64 Gly62 not aligned Gly498
P20906	C3LHY1	Gly39 Ser90 Glu65 Asn42 His40 not aligned Ser466
P20906	A1KGY5	Gly37 Thr83 Glu61 Asn40 Asp38 not aligned Gly419