M-CSA Mechanism and Catalytic Site Atlas

Transketolase (M-CSA:219)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of P23254, P29401

Reference Sequence	Homologue	His30 Glu418 His263 His481 His258 Lys244
P23254	A6KXB4	His28 not aligned His251 not aligned X X
P23254	A6VKQ4	His34 not aligned His257 not aligned X X
P23254	A5D2Z6	His43 Glu366 His296 His427 X X
P23254	Q74FC3	His43 Glu368 His297 His429 X X
P23254	P23254	His30 Glu418 His263 His481 X X
P23254	A0A0I9QGZ2	His28 Glu412 His263 His474 X X
P23254	A2BR27	His41 Glu370 His298 His431 X X
P23254	A3PCV0	His41 Glu370 His298 His431 X X
P23254	A4IQR7	His41 Glu367 His296 His428 X X
P23254	A6YB01	His30 Glu411 His266 His473 X X
P23254	A8G4R9	His41 Glu370 His298 His431 X X
P23254	B1HRX4	His41 Glu367 His296 His428 X X
P23254	B1I3J6	His42 Glu365 His296 His426 X X
P23254	B8D2I3	His43 Glu367 His297 His428 X X
P23254	C5D467	His41 Glu367 His296 His428 X X
P23254	D5AV94	His35 Glu415 His266 His477 X X
P23254	F4IW47	His103 Glu488 His340 His551 X X
P23254	O20250	His103 Glu488 His340 His551 X X
P23254	O67642	His56 Glu434 His289 His496 X X
P23254	O83571	His28 Glu412 His261 His474 X X
P23254	O93884	His36 Glu431 His273 His495 X X
P23254	O94039	His27 Glu415 His261 His478 X X
P23254	P06834	His38 Glu433 His275 His497 X X
P23254	P0CZ16	His35 Glu415 His266 His477 X X
P23254	P21725	His32 Glu417 His267 His479 X X
P23254	P21726	His32 Glu417 His267 His479 X X
P23254	P22976	His24 Glu408 His259 His470 X X
P23254	P27302	His26 Glu411 His261 His473 X X
P23254	P29277	His31 Glu408 His262 His470 X X
P23254	P29401	His37 Glu366 His258 Gln428 His258 Lys244
P23254	P33315	His30 Glu418 His263 His481 X X
P23254	P33570	His25 Glu410 His260 His472 X X
P23254	P34736	His27 Glu415 His261 His478 X X
P23254	P40142	His37 Glu366 His258 Gln428 X X
P23254	P43757	His26 Glu413 His261 His475 X X
P23254	P45694	His27 Glu411 His262 His473 X X
P23254	P46374	His91 not aligned not aligned not aligned X X
P23254	P46708	His45 Glu441 His283 His503 X X
P23254	P47312	His22 Glu397 His252 His459 X X
P23254	P50137	His37 Glu366 His258 Gln428 X X
P23254	P51010	His34 Glu414 His265 His476 X X
P23254	P51854	His46 Glu340 His232 Gln402 X X
P23254	P55574	Tyr32 not aligned His257 not aligned X X
P23254	P56900	His37 Glu415 His268 His477 X X
P23254	P57195	His26 Glu411 His261 His473 X X
P23254	P57927	His26 Glu413 His261 His475 X X
P23254	P57958	His26 Glu413 His261 His475 X X
P23254	P58333	His37 Glu415 His268 His477 X X
P23254	P59956	His45 Glu441 His283 His503 X X
P23254	P66962	His28 Glu410 His261 His472 X X
P23254	P66963	His28 Glu410 His261 His472 X X
P23254	P75611	His22 Glu397 His252 His459 X X
P23254	P99161	His28 Glu410 His261 His472 X X
P23254	P9WG24	His45 Glu441 His283 His503 X X
P23254	P9WG25	His45 Glu441 His283 His503 X X
P23254	Q12630	His30 Glu417 His262 His480 X X
P23254	Q2NKZ4	His37 Glu369 His261 Gln431 X X
P23254	Q2NL26	His46 Glu340 His232 Gln402 X X
P23254	Q39RT4	His43 Glu368 His297 His429 X X
P23254	Q3M4F6	His41 Glu370 His298 His431 X X
P23254	Q42675	His40 Glu425 His277 His488 X X
P23254	Q42676	not aligned Glu266 His118 His329 X X
P23254	Q42677	His36 Glu421 His273 His484 X X
P23254	Q43848	His103 Glu488 His340 His551 X X
P23254	Q4R6M8	His46 Glu340 His232 Gln402 X X
P23254	Q556J0	His31 Glu413 His267 His475 X X
P23254	Q58092	not aligned Glu60 not aligned His123 X X
P23254	Q58094	His32 not aligned His256 not aligned X X
P23254	Q5DZP0	His25 Glu410 His259 His472 X X
P23254	Q5E7R1	His26 Glu411 His260 His473 X X
P23254	Q5HG77	His28 Glu410 His261 His472 X X
P23254	Q5HPJ9	His28 Glu410 His261 His472 X X
P23254	Q5R1W6	His37 Glu366 His258 Gln428 X X
P23254	Q5R4C1	His37 Glu366 His258 Gln428 X X
P23254	Q5XAK5	His97 Glu477 His332 His539 X X
P23254	Q74CB0	His43 Glu368 His297 His429 X X
P23254	Q60103	His47 Glu432 His282 His494 X X
P23254	Q60HC7	His37 Glu366 His258 Gln428 X X
P23254	Q67NB6	His41 Glu363 His295 His423 X X
P23254	Q6AJQ1	His52 Glu376 His306 His437 X X
P23254	Q6B855	His37 Glu366 His258 Gln428 X X
P23254	Q6G9L6	His28 Glu410 His261 His472 X X
P23254	Q6GH64	His28 Glu410 His261 His472 X X
P23254	Q7MDD4	His25 Glu410 His259 His472 X X
P23254	Q7MHK7	His26 Glu411 His260 His473 X X
P23254	Q7NP63	His41 Glu372 His300 His433 X X
P23254	Q7SIC9	His38 Glu423 His275 His486 X X
P23254	Q87GY4	His25 Glu410 His259 His472 X X
P23254	Q87LK8	His26 Glu411 His260 His473 X X
P23254	Q89AY2	His26 Glu411 His261 His473 X X
P23254	Q8CPC7	His28 Glu410 His261 His472 X X
P23254	Q8D6H8	His25 Glu410 His259 His472 X X
P23254	Q8DCA2	His26 Glu411 His260 His473 X X
P23254	Q8KA26	His26 Glu411 His261 His473 X X
P23254	Q8NZX4	His97 Glu477 His332 His539 X X
P23254	Q8RWV0	His103 Glu488 His340 His551 X X
P23254	Q8YRU9	His31 Glu416 His268 His479 X X
P23254	Q8YZ80	His41 Glu370 His298 His431 X X
P23254	Q99MX0	Tyr46 Glu339 Tyr231 His401 X X
P23254	Q9D4D4	His39 Glu371 His263 Gln433 X X
P23254	Q9H0I9	Gln38 Glu370 His262 Gln432 X X
P23254	Q9KAD7	His28 Glu410 His262 His472 X X
P23254	Q9KLW7	His25 Glu411 His260 His473 X X
P23254	Q9KUP2	His26 Glu412 His261 His474 X X
P23254	Q9URM2	His32 Glu422 His268 His484 X X