M-CSA Mechanism and Catalytic Site Atlas

Arsenate reductase (M-CSA:143)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

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Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of P0A006

Reference Sequence	Homologue	Ser14 (main-N) Arg16 (main-N) Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 (main-N) Gly12 (main-N) Asn13 (main-N) Asp105 Cys82 Cys89 Ser17 Cys15 (main-N) Arg16
P0A006	P0A006	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	P0DKS5	Gly15 Lys17 Phe65 Lys67 Asn14 Ser37 Cys11 Val12 Gly13 Asn14 Glu106 Ala85 Leu89 Ser18 Gly16 Lys17
P0A006	P0DKS7	Gly12 Lys14 Ile62 Lys64 Asn11 Ser34 Cys8 Val9 Gly10 Asn11 Glu103 Asp82 Val86 Ser15 Gly13 Lys14
P0A006	Q8ENQ5	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	Q4LAA8	Ser14 Arg16 Thr63 Asn65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	Q4LAB5	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Ser11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	Q5WJS9	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	Q2FXF5	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	Q81NJ6	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	Q81BK3	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	Q9K8K8	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	Q65IV4	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	Q5HRI4	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	P74313	Ser12 Arg14 Thr61 Asp63 Asn11 Ser34 Cys8 Lys9 Arg10 Asn11 Asp103 Cys80 Cys82 Ser15 Cys13 Arg14
P0A006	Q49WS7	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	Q49UH1	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	C0ZEV2	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	P45947	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	B9E7M5	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	Q5HKB7	Ser14 Arg16 Thr63 Asn65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	B9IRF0	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	Q6GIZ3	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	A4INR2	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	A7GP55	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	Q8GJ74	Ser14 Arg16 Thr64 Asp66 Asn13 Ser37 Cys10 Thr11 Gly12 Asn13 Asp106 Cys83 Cys90 Ser17 Cys15 Arg16
P0A006	P0DKS8	Gly12 Lys14 Ile62 Lys64 Asn11 Ser34 Cys8 Val9 Gly10 Asn11 Glu103 Asp82 Val86 Ser15 Gly13 Lys14
P0A006	Q74NT6	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	Q2FFW6	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	C1F0A7	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	Q735E5	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	Q6HGP0	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	P0A005	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	Q639D2	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	Q2YTL3	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asn105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	P0DKS6	Gly15 Lys17 Phe65 Lys67 Asn14 Ser37 Cys11 Val12 Gly13 Asn14 Glu106 Ala85 Leu89 Ser18 Gly16 Lys17
P0A006	Q01257	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	B7HWU2	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	B7INE4	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	C3P101	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	Q8CQF5	Ser14 Arg16 Thr63 Asn65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	C3LDK1	Ser15 Arg17 Thr64 Asp66 Asn14 Ser37 Cys11 Thr12 Gly13 Asn14 Asp106 Cys83 Cys90 Ser18 Cys16 Arg17
P0A006	A6QHV6	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	Q5HF01	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16
P0A006	A8Z4K0	Ser14 Arg16 Thr63 Asp65 Asn13 Ser36 Cys10 Thr11 Gly12 Asn13 Asp105 Cys82 Cys89 Ser17 Cys15 Arg16