M-CSA Mechanism and Catalytic Site Atlas

Camphor 5-monooxygenase (M-CSA:133)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of P00183

Reference Sequence	Homologue	Asp252 Thr253 Cys358 Leu359 (main-N) Gly360 (main-N) Arg187
P00183	P00183	Asp252 Thr253 Cys358 Leu359 Gly360 Arg187
P00183	P23295	Ala242 Thr243 Cys352 Ile353 Ala354 not aligned
P00183	Q00441	Glu244 Ala245 Cys351 Met352 Gly353 not aligned
P00183	P53554	Glu238 Thr239 Cys345 Leu346 Gly347 not aligned
P00183	O34374	Glu242 Thr243 Cys349 Leu350 Gly351 not aligned
P00183	P9WPL5	Glu233 Thr234 Cys340 Leu341 Gly342 not aligned
P00183	P48635	Ile230 Thr231 Cys339 Leu340 Gly341 not aligned
P00183	A0R4Q6	Glu236 Thr237 Cys343 Leu344 Gly345 not aligned
P00183	A0R4Y3	Glu254 Thr255 Cys360 Ile361 Gly362 not aligned
P00183	O31785	Glu244 Thr245 Cys352 Leu353 Gly354 not aligned
P00183	P9WPL9	Glu273 Thr274 Cys381 Leu382 Gly383 not aligned
P00183	P9WPN5	Asp246 Thr247 Cys354 Leu355 Gly356 not aligned
P00183	Q9FCA6	Glu244 Ala245 Cys353 Pro354 Gly355 not aligned
P00183	Q9KZF5	Glu247 Ala248 Cys356 Thr357 Gly358 not aligned
P00183	P33271	Glu244 Thr245 Cys352 Val353 Gly354 not aligned
P00183	P9WPP3	Glu270 Thr271 Cys379 Leu380 Gly381 not aligned
P00183	Q53215	Asp258 Thr259 Cys364 His365 Gly366 not aligned
P00183	O08469	Glu251 Thr252 Cys359 Leu360 Gly361 not aligned
P00183	P9WPP1	Glu271 Thr272 Cys377 Ile378 Gly379 not aligned
P00183	Q0S7M1	Glu306 Thr307 Cys412 Leu413 Gly414 not aligned
P00183	P9WPL3	Asp235 Thr236 Cys342 Leu343 Gly344 not aligned
P00183	D5E3H2	Glu253 Thr254 Cys360 Leu361 Gly362 not aligned
P00183	Q825I8	Glu244 Thr245 Cys351 Leu352 Gly353 not aligned
P00183	Q59203	Glu240 Ser241 Cys350 Ile351 Gly352 not aligned
P00183	P9WPL7	Asp238 Thr239 Cys346 Pro347 Ala348 not aligned
P00183	P9WPP5	Glu242 Thr243 Cys350 Leu351 Gly352 not aligned
P00183	P9WPP7	Ile236 Ser237 Cys345 Pro346 Gly347 not aligned
P00183	Q9PGC5	Glu241 Thr242 Cys348 Leu349 Gly350 not aligned
P00183	O34926	Glu236 Pro237 Cys353 Val354 Gly355 not aligned
P00183	P9WPN7	Glu328 Ser329 Cys435 Pro436 Gly437 not aligned
P00183	Q6N8N2	Asp254 Thr255 Cys361 Val362 Gly363 not aligned
P00183	P9WPN9	Glu256 Thr257 Cys363 Leu364 Gly365 not aligned
P00183	Q9PGE6	Glu241 Thr242 Cys348 Leu349 Gly350 not aligned
P00183	Q59204	Val257 Thr258 Cys376 Leu377 Gly378 not aligned
P00183	P55544	Glu239 Ser240 Cys349 Ile350 Gly351 not aligned
P00183	C4B644	Glu239 Thr240 Cys347 Leu348 Gly349 not aligned
P00183	E3VWI3	Glu235 Thr236 Cys347 Ile348 Gly349 not aligned
P00183	O87605	Glu246 Thr247 Cys354 Ile355 Gly356 not aligned
P00183	P0A515	Ile236 Ser237 Cys345 Pro346 Gly347 not aligned
P00183	P18326	Glu247 Thr248 Cys355 Leu356 Gly357 not aligned
P00183	P33006	Asp270 Thr271 Cys377 Leu378 Gly379 not aligned
P00183	P9WPN8	Glu256 Thr257 Cys363 Leu364 Gly365 not aligned
P00183	Q06069	Glu246 Thr247 Cys355 Leu356 Gly357 Phe176
P00183	Q59523	Glu237 Ser238 Cys346 Leu347 Gly348 not aligned
P00183	Q8RN04	Asp239 Asn240 Cys347 Leu348 Gly349 not aligned
P00183	Q8RN03	Glu248 Thr249 Cys356 Val357 Gly358 not aligned
P00183	Q8VQF6	Asp241 Asn242 Cys347 Leu348 Gly349 not aligned
P00183	Q83WF5	Glu230 Thr231 Cys337 Leu338 Gly339 not aligned
P00183	Q9KIZ4	Asp257 Thr258 Cys365 Pro366 Gly367 not aligned
P00183	P63714	Glu328 Ser329 Cys435 Pro436 Gly437 not aligned
P00183	P9WPP0	Glu271 Thr272 Cys377 Ile378 Gly379 not aligned
P00183	P9WPL4	Glu207 Thr208 Cys314 Leu315 Gly316 not aligned
P00183	P63708	Glu242 Thr243 Cys350 Leu351 Gly352 not aligned
P00183	P23296	Gly222 Thr223 Cys330 Leu331 Gly332 not aligned
P00183	P24466	Asp261 Thr262 Cys369 Leu370 Gly371 not aligned
P00183	P63712	Glu256 Thr257 Cys363 Leu364 Gly365 not aligned
P00183	Q87AX5	Glu241 Thr242 Cys348 Leu349 Gly350 not aligned
P00183	P0A517	Glu270 Thr271 Cys379 Leu380 Gly381 not aligned
P00183	P9WPP4	Glu242 Thr243 Cys350 Leu351 Gly352 not aligned
P00183	Q00616	Ala242 Thr243 Cys352 Ile353 Ala354 not aligned
P00183	P26911	Glu254 Thr255 Cys361 Leu362 Gly363 not aligned
P00183	Q59723	Glu248 Thr249 Cys355 Val356 Gly357 not aligned
P00183	P43492	Glu267 Thr268 Cys375 Leu376 Gly377 Gly197
P00183	P63722	Glu273 Thr274 Cys381 Leu382 Gly383 not aligned
P00183	P9WPN6	Glu328 Ser329 Cys435 Pro436 Gly437 not aligned
P00183	P9WPL6	Asp238 Thr239 Cys346 Pro347 Ala348 not aligned
P00183	Q9ZHQ1	Glu262 Thr263 Cys369 Leu370 Gly371 not aligned
P00183	Q87AV9	Glu241 Thr242 Cys348 Leu349 Gly350 not aligned
P00183	E3VWJ9	Glu235 Thr236 Cys347 Ile348 Gly349 not aligned
P00183	Q59831	Glu251 Thr252 Cys359 Leu360 Gly361 not aligned
P00183	P27632	Glu244 Thr245 Cys351 Leu352 Gly353 not aligned
P00183	B4XY99	Asp239 Asn240 Cys347 Met348 Gly349 not aligned
P00183	Q12599	Ala247 Thr248 Cys357 Ile358 Ala359 not aligned
P00183	Q9L9F9	Glu250 Thr251 Cys357 Leu358 Gly359 not aligned
P00183	P9WPP2	Glu270 Thr271 Cys379 Leu380 Gly381 not aligned
P00183	P63710	Glu271 Thr272 Cys377 Ile378 Gly379 not aligned
P00183	P9WPL2	Asp235 Thr236 Cys342 Leu343 Gly344 not aligned
P00183	P14762	Glu247 Thr248 Cys356 Leu357 Gly358 Tyr177
P00183	P63724	Asp235 Thr236 Cys342 Leu343 Gly344 not aligned
P00183	P9WPP6	Ile236 Ser237 Cys345 Pro346 Gly347 not aligned
P00183	P18327	Glu244 Thr245 Cys352 Leu353 Gly354 not aligned
P00183	Q8RN05	Asp235 Gln236 Cys342 Leu343 Gly344 not aligned
P00183	Q84HB6	Glu241 Thr242 Cys350 Leu351 Gly352 not aligned
P00183	P9WPN4	Asp246 Thr247 Cys354 Leu355 Gly356 not aligned
P00183	P9WPL8	Glu273 Thr274 Cys381 Leu382 Gly383 not aligned
P00183	P46373	Glu241 Thr242 Cys349 Leu350 Gly351 not aligned
P00183	P0DPQ7	Gln248 Glu249 Cys356 Ala357 Gly358 not aligned