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PDBsum entry 9ofc
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Immune system, hydrolase
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PDB id
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9ofc
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PDB id:
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| Name: |
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Immune system, hydrolase
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Title:
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Cryoem structure of cad1 bound with ca4 and atp, hexamer with three intact dimers
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Structure:
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Crispr-associated ring nuclease and adenosine deaminase, subunit a. Chain: a, b, g, h, k, l. Engineered: yes. Ca4 cleavage product, a2>p. Chain: c, d, i, j, m, n. Engineered: yes
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Source:
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Thermoanaerobaculum aquaticum. Organism_taxid: 1312852. Gene: eg19_07865. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 1312852
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Authors:
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Y.Zhao,H.Li
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Key ref:
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M.Roth
et al.
Sequential conformational activation of a carf-Fused adenosine deaminase by cyclic oligoadenylates.
To be published,
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PubMed id:
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Date:
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29-Apr-25
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Release date:
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20-Aug-25
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PROCHECK
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Headers
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References
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A0A062XY19
(A0A062XY19_9BACT) -
adenosine deaminase from Thermoanaerobaculum aquaticum
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Seq:
Struc:
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625 a.a.
605 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Enzyme class:
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E.C.3.5.4.4
- adenosine deaminase.
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Reaction:
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1.
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adenosine + H2O + H+ = inosine + NH4+
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2.
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2'-deoxyadenosine + H2O + H+ = 2'-deoxyinosine + NH4+
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adenosine
Bound ligand (Het Group name = )
matches with 76.00% similarity
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+
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H2O
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+
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H(+)
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=
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inosine
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+
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NH4(+)
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2'-deoxyadenosine
Bound ligand (Het Group name = )
matches with 72.00% similarity
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+
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H2O
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+
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H(+)
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=
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2'-deoxyinosine
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+
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NH4(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
