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PDBsum entry 8ebc

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
8ebc

 

 

 

 

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Contents
Protein chains
337 a.a.
355 a.a.
Ligands
IMP ×6
GOL
FMT ×2
Waters ×150
PDB id:
8ebc
Name: Oxidoreductase
Title: Crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from listeria monocytogenes in the complex with imp
Structure: Lmo0132 protein. Chain: a, b, c, d, f, e. Engineered: yes
Source: Listeria monocytogenes egd-e. Organism_taxid: 169963. Strain: atcc baa-679 / egd-e. Gene: lmo0132. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: gold.
Resolution:
2.50Å     R-factor:   0.196     R-free:   0.239
Authors: Y.Kim,N.Maltseva,M.Makowska-Grzyska,J.Osipiuk,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid),Center For Structural Biology Of Infectious Diseases (Csbid)
Key ref: Y.Kim et al. Crystal structure of the catalytic domain of the inos monophosphate dehydrogenase from listeria monocytogen the complex with imp. To be published, .
Date:
31-Aug-22     Release date:   07-Sep-22    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q8YAJ3  (Q8YAJ3_LISMO) -  Lmo0132 protein from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Seq:
Struc:
502 a.a.
337 a.a.*
Protein chains
Pfam   ArchSchema ?
Q8YAJ3  (Q8YAJ3_LISMO) -  Lmo0132 protein from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Seq:
Struc:
502 a.a.
355 a.a.
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: Chains A, B, C, D, F, E: E.C.1.1.1.205  - Imp dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
AMP and GMP Biosynthesis
      Reaction: IMP + NAD+ + H2O = XMP + NADH + H+
IMP
+
NAD(+)
Bound ligand (Het Group name = IMP)
corresponds exactly
+ H2O
= XMP
+ NADH
+ H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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