EC 1.1.1.205 - IMP dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.1.1.205

Names

Accepted name:
IMP dehydrogenase
Other names:
IMP oxidoreductase
inosinate dehydrogenase
inosine 5'-monophosphate dehydrogenase
inosine monophosphate dehydrogenase
inosine monophosphate oxidoreductase
inosine-5'-phosphate dehydrogenase
inosinic acid dehydrogenase
Systematic name:
IMP:NAD+ oxidoreductase

Reaction

Comments:

The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00391
Structural data: CSA , EC2PDB
Gene Ontology: GO:0003938
CAS Registry Number: 9028-93-7
UniProtKB/Swiss-Prot: (87) [show] [UniProt]

References

  1. Magasanik, B., Moyed, H.S. and Gehring, L.B.
    Enzymes essential for the biosynthesis of nucleic acid guanine; inosine 5'-phosphate dehydrogenase of Aerobacter aerogenes.
    J. Biol. Chem. 226: 339-350 (1957). [PMID: 13428767]
  2. Turner, J.F. and King, J.E.
    Inosine 5-phosphate dehydrogenase of pea seeds.
    Biochem. J. 79: 147 (1961). [PMID: 13778733]

[EC 1.1.1.205 created 1961 as EC 1.2.1.14, transferred 1984 to EC 1.1.1.205]