PDBsum entry 3k3c

Signaling protein

PDB id: 3k3c

Contents

Protein chains

152 a.a. *

Ligands

PLM ×2

SO4 ×6

GOL ×11

Waters ×657

* Residue conservation analysis

PDB id:

3k3c

Name:

Signaling protein

Title:

The n-terminal pas domain crystal structure of rv1364c from mycobacterium tuberculosis at 1.62

Structure:

Protein rv1364c/mt1410. Chain: a, b, c, d. Fragment: unp residues 1-156. Engineered: yes

Source:

Mycobacterium tuberculosis. Organism_taxid: 1773. Strain: h37rv. Gene: mt1410, mtcy02b10.28c, rv1364c. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.62Å R-factor: 0.183 R-free: 0.212

Authors:

J.King-Scott,P.A.Tucker

Key ref:

J.King-Scott and p.a.tucker The n-Terminal pas domain crystal structure of rv1364 mycobacterium tuberculosis at 1.62. To be published, .

Date:

02-Oct-09 Release date: 29-Sep-10

Protein chains

P9WLZ7  (Y1364_MYCTU) -  Multidomain regulatory protein Rv1364c from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Seq: 653 a.a.

Struc: 152 a.a.

Enzyme reactions

• Enzyme class 2: E.C.2.7.11.1 - non-specific serine/threonine protein kinase.
• Reaction:
  1. L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H⁺
  2. L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H⁺
• Enzyme class 3: E.C.3.1.3.16 - protein-serine/threonine phosphatase.
• Reaction:
  1. O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate
  2. O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site