Ligand clusters for UniProt code Q9C0B1

Ligand clusters for Q9C0B1: Alpha-ketoglutarate-dependent dioxygenase FTO from Homo sapiens

		4 ligand clusters Cluster 1. 26 ligand types 53 ligands Cluster 2. 1 ligand type 1 ligand Cluster 3. 1 ligand type 1 ligand Cluster 4. 1 ligand type 1 ligand
Representative protein: 4ie6A

Structures

PDB		Schematic diagram
4ie6A
4qhoA
4ie5A
4idzA
6akwA
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Cluster 1 contains 26 ligand types (of which only 20 are listed. Click for all)

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Ligand		Description
_Zn		1. Metal: _ZN × 8 PDB codes: 4ie0(A), 4ie4(A), 4ie5(A), 4ie6(A), 4ie7(A), 4qho(A), 6aej(A), 6ak4(A).
		2. Ligand: GOL × 5 glycerin Glycerol PDB codes: 4idz(A), 4ie0(A), 4ie4(A), 4ie5(A), 4qkn(A).
_Mn		3. Metal: _MN × 4 PDB codes: 4qkn(A), 4zs2(A), 4zs3(A), 5zmd(A).
		4. Ligand: FLU × 1 fluorescein 2-(6-Hydroxy-3-Oxo-3h-Xanthen-9-Yl)-Benzoic acid PDB code: 4zs2(A).
		5. Ligand: JMS × 1 meclofenamic acid 2-[(2,6-Dichloro-3-Methyl-Phenyl)amino]benzoic acid PDB code: 4qkn(A).
		6. Ligand: PD9 × 1 entacapone (~{E})-2-Cyano-~{N},~{N}-Diethyl-3-[3-Nitro-4,5- Bis(oxidanyl)phenyl]prop-2-Enamide PDB code: 6ak4(A).
		7. Ligand: AKG × 5 2-Oxoglutaric acid PDB codes: 4zs2(A), 4zs3(A), 5dab(A), 5f8p(A), 6akw(A).
_Ni		8. Metal: _NI × 5 PDB codes: 4cxw(A), 4cxx(A), 4cxy(A), 4idz(A).
		9. Ligand: OGA × 4 N-Oxalylglycine PDB codes: 3lfm(A), 4idz(A), 4qkn(A), 5zmd(A).
Fe2		10. Metal: FE2 × 3 PDB codes: 3lfm(A), 5dab(A), 5f8p(A).
		11. Ligand: 3DT × 1 3-Methylthymidine PDB code: 3lfm(A).
		12. Ligand: 58W × 1 N-(5-Chloro-2,4-Dihydroxyphenyl)-1- Phenylcyclobutanecarboxamide PDB code: 5dab(A).
		13. Ligand: 640 × 1 (2e)-4-{N'-[4-(4-Tert-Butyl-Benzyl)-Pyridine-3- Carbonyl]-Hydrazino}-4-Oxo-But-2-Enoic acid PDB code: 4cxx(A).
		14. Ligand: 6MK × 1 (2e)-4-[N'-(4-Benzyl-Pyridine-3-Carbonyl)-Hydrazino]-4- Oxo-But-2-Enoic acid PDB code: 4cxw(A).
		15. Ligand: 7YC × 1 (E)-3-[3-Nitro-4,5-Bis(oxidanyl)phenyl]-2-(1,3- Oxazinan-3-Ylcarbonyl)prop-2-Enenitrile PDB code: 6aej(A).
		16. Ligand: 8S3 × 1 2-[[2,6-Bis(chloranyl)-4-(3,5-Dimethyl-1,2-Oxazol-4- Yl)phenyl]amino]benzoic acid PDB code: 6akw(A).
		17. Ligand: 8XQ × 1 8-Hydroxyquinoline-5-Carboxylic acid PDB code: 4ie4(A).
		18. Ligand: A4F × 1 5-Amino-2-(6-Hydroxy-3-Oxo-3h-Xanthen-9-Yl)benzoic acid PDB code: 4zs3(A).
		19. Ligand: DGR × 1 (E)-4-(2-Nicotinoylhydrazinyl)-4-Oxobut-2-Enoic acid PDB code: 4cxy(A).
		20. Ligand: FIJ × 1 4-Chloranyl-6-[(2~{s})-6-Chloranyl-2,4,4-Trimethyl-7- Oxidanyl-3~{h}-Chromen-2-Yl]benzene-1,3-Diol PDB code: 5f8p(A).
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Cluster 2 contains 1 ligand type

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 4ie5(A).

Cluster 3 contains 1 ligand type

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Ligand		Description
		1. Ligand: SO4 × 1 Sulfate ion PDB code: 5f8p(A).

Cluster 4 contains 1 ligand type

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Ligand		Description
_Cl		1. Metal: _CL × 1 PDB code: 5dab(A).