Ligand clusters for UniProt code Q02293

Ligand clusters for Q02293: Protein farnesyltransferase subunit beta from Rattus norvegicus

		Top 6 (of 8) ligand clusters Cluster 1. 50 ligand types 155 ligands Cluster 2. 1 ligand type 2 ligands Cluster 3. 1 ligand type 1 ligand Cluster 4. 1 ligand type 2 ligands Cluster 5. 1 ligand type 2 ligands Cluster 6. 1 ligand type 1 ligand
Representative protein: 1ft1B

Structures

PDB		Schematic diagram
1ft1B
3e30B
3e32B
4gtmB
3euvB
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Cluster 1 contains 50 ligand types (of which only 20 are listed. Click for all)

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Ligand		Description
_Zn		1. Metal: _ZN × 46 PDB codes: 1d8d(B), 1fpp(B), 1ft1(B), 1ft2(B), 1fti(B), 1hz7(B), 1jcr(B), 1jcs(B), 1kzo(B), 1kzp(B), 1kzr(B), 1n94(B), 1n95(B), 1n9a(B), 1ni1(B), 1nl4(B), 1o1r(B), 1o1s(B), 1o1t(B), 1o5m(B), 1qbq(B), 1sa5(B), 1tn7(B), 1tn8(B), 1x81(B), 2bed(B), 2fti(B), 2r2l(B), 2zir(B), 2zis(B), 3dpy(B), 3e30(B), 3e32(B), 3e33(B), 3e34(B), 3eu5(B), 3euv(B), 3fti(B), 3ksl(B), 3ksq(B), 3pz4(B), 4gtm(B), 4gto(B), 4gtp(B), 4gtq(B), 4gtr(B).
		2. Ligand: ACY × 11 acetic acid Acetic acid PDB codes: 1jcr(B), 1jcs(B), 1kzo(B), 1kzp(B), 1sa5(B), 1tn7(B), 1tn8(B), 2zis(B), 3dpy(B).
		3. Ligand: DMS × 8 dimethyl sulfoxide Dimethyl sulfoxide PDB codes: 4gtm(B), 4gto(B), 4gtp(B), 4gtr(B),
_Mg		4. Metal: _MG × 2 PDB codes: 1hz7(B), 1kzr(B).
		5. Ligand: GOL × 1 glycerin Glycerol PDB code: 2zir(B).
		6. Ligand: FPP × 27 Farnesyl diphosphate PDB codes: 1fpp(B), 1ft2(B), 1fti(B), 1hz7(B), 1jcr(B), 1kzo(B), 1kzr(B), 1o5m(B), 1sa5(B), 2bed(B), 2fti(B), 2r2l(B), 2zir(B), 2zis(B), 3dpy(B), 3e30(B), 3e32(B), 3e33(B), 3e34(B), 3fti(B), 3ksq(B), 3pz4(B), 4gtm(B), 4gto(B), 4gtp(B), 4gtq(B), 4gtr(B).
		7. Ligand: HFP × 6 Alpha-Hydroxyfarnesylphosphonic acid PDB codes: 1n94(B), 1n95(B), 1n9a(B), 1ni1(B), 1nl4(B), 1qbq(B).
		8. Ligand: ACT × 5 Acetate ion PDB codes: 1d8d(B), 1d8e(B).
		9. Ligand: FII × 5 [(3,7,11-Trimethyl-Dodeca-2,6,10-Trienyloxycarbamoyl)- Methyl]-Phosphonic acid PDB codes: 1d8d(B), 1d8e(B), 1jcs(B), 1tn7(B), 1tn8(B).
		10. Ligand: FAR × 2 Farnesyl PDB codes: 1kzo(B), 1kzp(B).
		11. Ligand: GBO × 2 (2e,6e)-3,7-Dimethyl-8-({5-[(3as,4s,6ar)-2- Oxohexahydro-1h-Thieno[3,4-D]imidazol-4- Yl]pentanoyl}amino)octa-2,6-Dien-1-Yl trihydrogen diphosphate PDB codes: 3eu5(B), 3euv(B).
		12. Ligand: THR-LYS-CYS-VAL-ILE-MET × 2 PDB codes: 1d8e(B), 1kzo(B).
		13. Ligand: 1NH × 1 (2e,6e)-8-[(3-Benzoylbenzyl)oxy]-3,7-Dimethylocta-2,6- Dienyl trihydrogen diphosphate PDB code: 1o1s(B).
		14. Ligand: 2C5 × 1 2-Chloro-5-(3-Chloro-Phenyl)-6-[(4-Cyano-Phenyl)-(3- Methyl-3h-Imidazol-4-Yl)- Methoxymethyl]- Nicotinonitrile PDB code: 1ni1(B).
		15. Ligand: 2NH × 1 N-Acetyl-S-[(2e,6e)-3,7,11-Trimethyldodeca-2,6,10- Trienyl]-L-Cysteinyl-D-Valyl-L-Isoleucyl-L- Methionine PDB code: 1o1t(B).
		16. Ligand: 336 × 1 4-{2-[4-(3,10-Dibromo-8-Chloro-6,11-Dihydro-5h-Benzo[5, 6]cyclohepta[1,2-B]pyridin-11-Yl)piperidin- 1-Yl]-2- Oxoethyl}piperidine-1-Carboxamide PDB code: 1o5m(B).
		17. Ligand: 3PZ × 1 (3r)-3-Benzyl-4-[(4-Methoxyphenyl)sulfonyl]-1-[(1- Methyl-1h-Imidazol-5-Yl)methyl]-2,3,4,5- Tetrahydro-1h- 1,4-Benzodiazepine-7-Carbonitrile PDB code: 3pz4(B).
		18. Ligand: 736 × 1 (11s)-8-Chloro-11-[1-(Methylsulfonyl)piperidin-4-Yl]-6- Piperazin-1-Yl-11h- Benzo[5,6]cyclohepta[1,2-B]pyridine PDB code: 2bed(B).
		19. Ligand: 7TM × 1 4-({(3r)-7-Cyano-4-[(4-Methoxyphenyl)sulfonyl]-1-[(1- Methyl-1h-Imidazol-5-Yl)methyl]-2,3,4,5- Tetrahydro-1h- 1,4-Benzodiazepin-3-Yl}methyl)phenyl hexylcarbamate PDB code: 4gtm(B).
		20. Ligand: 7TO × 1 4-({(3r)-7-Cyano-4-[(4-Methoxyphenyl)sulfonyl]-1-[(1- Methyl-1h-Imidazol-5-Yl)methyl]-2,3,4,5- Tetrahydro-1h- 1,4-Benzodiazepin-3-Yl}methyl)phenyl trifluoromethanesulfonate PDB code: 4gto(B).
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Cluster 2 contains 1 ligand type

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Ligand		Description
		1. Ligand: GOL × 2 glycerin Glycerol PDB codes: 2zir(B), 2zis(B).

Cluster 3 contains 1 ligand type

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Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 2zir(B).

Cluster 4 contains 1 ligand type

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Ligand		Description
		1. Ligand: GOL × 2 glycerin Glycerol PDB codes: 2zir(B), 2zis(B).

Cluster 5 contains 1 ligand type

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Ligand		Description
		1. Ligand: GOL × 2 glycerin Glycerol PDB codes: 2zir(B), 2zis(B).

Cluster 6 contains 1 ligand type

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Ligand		Description
		1. Ligand: PO4 × 1 Phosphate ion PDB code: 1fpp(B).