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List of PDB entries containing Het Group PTR

Het Group: PTR   PDB code: Use mouse to move/zoom 3D Viewers:	Links  Ligands KEGG DrugBank PDBeChem HIC-Up Ligand Expo
Name: O-Phosphotyrosine
Synonym(s): Phosphonotyrosine
Formula: C9H12NO6P
Compound type: L-Peptide linking

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PDB id		Count		Name		Method		Date
1a07		×1		C-src (sh2 domain) complexed with ace-malonyl tyr-glu-(n,n-dipentyl amine)		X-ray(2.2Å)		08-Apr-98
1a1b		×1		C-src (sh2 domain) complexed with ace-phosphotyr-glu-(n,n-dipentyl amine)		X-ray(2.2Å)		08-Apr-98
1a1c		×1		C-src (sh2 domain) complexed with ace-phosphotyr-glu-(n-me(-(ch2)3- cyclopentyl))		X-ray(2.4Å)		08-Apr-98
1a1e		×1		C-src (sh2 domain) complexed with ace-phosphotyr-glu-(3- butylpiperidine)		X-ray(2.2Å)		08-Apr-98
1a31		×0		Human reconstituted DNA topoisomerase i in covalent complex with a 22 base pair DNA duplex		X-ray(2.1Å)		28-Aug-98
1a81		×10		Crystal structure of the tandem sh2 domain of the syk kinase bound to a dually tyrosine-phosphorylated itam		X-ray(3Å)		21-Oct-98
1ad5		×1		Src family kinase hck-amp-pnp complex		X-ray(2.6Å)		15-May-97
1aot		×0		Nmr structure of the fyn sh2 domain complexed with a phosphotyrosyl peptide, minimized average structure		NMR(1 model)		14-Jan-98
1aou		×0		Nmr structure of the fyn sh2 domain complexed with a phosphotyrosyl peptide, 22 structures		NMR(22 models)		14-Jan-98
1aya		×1		Crystal structures of peptide complexes of the amino-terminal sh2 domain of the syp tyrosine phosphatase		X-ray(2.05Å)		31-Aug-94
1ayb		×0		Crystal structures of peptide complexes of the amino-terminal sh2 domain of the syp tyrosine phosphatase		X-ray(3Å)		31-Aug-94
1ayc		×0		Crystal structures of peptide complexes of the amino-terminal sh2 domain of the syp tyrosine phosphatase		X-ray(2.3Å)		31-Aug-94
1bf5		×0		Tyrosine phosphorylated stat-1/DNA complex		X-ray(2.9Å)		12-Aug-98
1bg1		×0		Transcription factor stat3b/DNA complex		X-ray(2.25Å)		13-Jan-99
1bm2		×0		Grb2-sh2 domain in complex with cyclo-[n-alpha-acetyl-l-thi alysyl-o- phosphotyrosyl-valyl-asparagyl-valyl-prolyl] (pkf273-791)		X-ray(2.1Å)		05-Aug-98
1bmb		×0		Grb2-sh2 domain in complex with kpfy Vnvef (pkf270-974)		X-ray(1.8Å)		29-Jul-98
1cm8		×1		Phosphorylated map kinase p38-gamma		X-ray(2.4Å)		17-May-00
1crx		×0		Cre recombinase/DNA complex reaction intermediate i		X-ray(2.4Å)		14-Oct-98
1csy		×0		Syk tyrosine kinasE C-terminal sh2 domain complexed with a phosphopeptidefrom the gamma chain of the high affinity immunoglobin g receptor, nmr		NMR(20 models)		08-Nov-96
1csz		×0		Syk tyrosine kinasE C-terminal sh2 domain complexed with a phosphopeptidefrom the gamma chain of the high affinity immunoglobin g receptor, nmr		NMR(1 model)		08-Nov-96
1d4w		×1		Crystal structure of the xlp protein sap in complex with slam phosphopeptide		X-ray(1.8Å)		14-Oct-99
1een		×0		Crystal structure of protein tyrosine phosphatase 1b complexed with acetyl-d-a-d-bpa-ptyr-l-i-p-q-q-g		X-ray(1.9Å)		01-Feb-01
1eeo		×0		Crystal structure of protein tyrosine phosphatase 1b complexed with acetyl-e-l-e-f-ptyr-m-d-y-e-nh2		X-ray(1.8Å)		01-Feb-01
1f1w		×0		Src sh2 thref1trp mutant complexed with the phosphopeptide s(ptr)vnvqn		X-ray(2.1Å)		06-Jul-00
1f5d		×0		Human vh1-related dual-specificity phosphatase c124s mutant- peptide complex		X-ray(2.75Å)		13-Dec-00
1fbv		×0		Structure of a cbl-ubch7 complex: ring domain function in ubiquitin- protein ligases		X-ray(2.9Å)		30-Aug-00
1fhr		×0		Solution structure of the fha2 domain of rad53 complexed with a phosphotyrosyl peptide		NMR(20 models)		18-Oct-00
1fmk		×0		Crystal structure of human tyrosine-protein kinasE C-src		X-ray(1.5Å)		20-Aug-97
1fpr		×0		Crystal structure of the complex formed between the catalytic domain of shp-1 and an in vitro peptide substrate py469 derived from shps-1.		X-ray(2.5Å)		07-Mar-01
1fu5		×0		Nmr structure of the n-sh2 domain of the p85 subunit of pi3-kinase complexed to a doubly phosphorylated peptide derived from polyomavirus middle t antigen		NMR(1 model)		21-Feb-01
1fyr		×3		Dimer formation through domain swapping in the crystal structure of the grb2-sh2 ac-pyvnv complex		X-ray(2.4Å)		06-Dec-00
1g1f		×0		Crystal structure of protein tyrosine phosphatase 1b complexed with a tri-phosphorylated peptide (rdi(ptr)etd(ptr)(ptr)rk) from the insulin receptor kinase		X-ray(2Å)		17-Jan-01
1g1g		×0		Crystal structure of protein tyrosine phosphatase 1b complexed with a mono-phosphorylated peptide (etdy(ptr)rkggkgll) from the insulin receptor kinase		X-ray(2.2Å)		17-Jan-01
1g1h		×0		Crystal structure of protein tyrosine phosphatase 1b complexed with a bis-phosphorylated peptide (etd(ptr)(ptr)rkggkgll) from the insulin receptor kinase		X-ray(2.4Å)		17-Jan-01
1gag		×0		Crystal structure of the insulin receptor kinase in complex with a bisubstrate inhibitor		X-ray(2.7Å)		17-Jan-01
1gng		×1		Glycogen synthase kinase-3 beta (gsk3) complex with frattide peptide		X-ray(2.6Å)		03-Oct-02
1h9o		×0		Phosphatidylinositol 3-kinase, p85-alpha subunit: c-terminal sh2 domain complexed with a tyr751 phosphopeptide from the pdgf receptor, crystal structure at 1.79 a		X-ray(1.79Å)		19-Mar-01
1hcs		×0		Nmr structure of the human src sh2 domain complex		NMR(1 model)		15-Sep-95
1hct		×0		Nmr structure of the human src sh2 domain complex		NMR(23 models)		15-Sep-95
1i3z		×0		Murine eat2 sh2 domain in complex with slam phosphopeptide		X-ray(2.15Å)		08-Apr-03
1ir3		×0		Phosphorylated insulin receptor tyrosine kinase in complex with peptide substrate and atp analog		X-ray(1.9Å)		07-Jan-98
1irs		×0		Irs-1 ptb domain complexed with a il-4 receptor phosphopeptide, nmr, minimized average structure		NMR(1 model)		15-May-97
1j4k		×0		Solution structure of the fha2 domain of rad53 complexed with a phosphotyrosyl peptide derived from rad9		NMR(1 model)		05-Dec-01
1j4x		×0		Human vh1-related dual-specificity phosphatase c124s mutant-peptide complex		X-ray(2.75Å)		19-Dec-01
1ju5		×0		Ternary complex of an crk sh2 domain, crk-derived phophopeptide, and abl sh3 domain by nmr spectroscopy		NMR(1 model)		06-Nov-02
1jyq		×1		Xray structure of grb2 sh2 domain complexed with a highly affine phospho peptide		X-ray(2Å)		13-Mar-02
1jyr		×0		Xray structure of grb2 sh2 domain complexed with a phosphorylated peptide		X-ray(1.55Å)		13-Mar-02
1k2m		×0		Solution structure of the fha2 domain of rad53 complexed with a phosphotyrosyl peptide derived from rad9		NMR(22 models)		05-Dec-01
1k3a		×0		Structure of the insulin-like growth factor 1 receptor kinase		X-ray(2.1Å)		28-Nov-01
1k4s		×0		Human DNA topoisomerase i in covalent complex with a 22 base pair DNA duplex		X-ray(3.2Å)		04-Dec-02
1k4t		×0		Human DNA topoisomerase i (70 kda) in complex with the poison topotecan and covalent complex with a 22 base pair DNA duplex		X-ray(2.1Å)		04-Dec-02
1ka6		×0		Sap/sh2d1a bound to peptide n-py		NMR(1 model)		07-Nov-01
1kc2		×0		Structure of the triple (lys(beta)d3ala, asp(beta)c8ala, aspcd2ala) mutant of the src sh2 domain bound to the pqpyeeipi peptide		X-ray(2.1Å)		17-Apr-02
1ksw		×0		Structure of human c-src tyrosine kinase (thr338gly mutant) in complex with n6-benzyl adp		X-ray(2.8Å)		27-Feb-02
1lcj		×0		Sh2 (src homology-2) domain of human p56-lck tyrosine kinase complexed with the 11 residue phosphotyrosyl peptide epqpyeeipiyl		X-ray(1.8Å)		15-Oct-95
1lck		×0		Sh3-sh2 domain fragment of human p56-lck tyrosine kinase complexed with the 10 residue synthetic phosphotyrosyl peptide tegqpyqpqpa		X-ray(2.5Å)		15-Oct-95
1lkk		×0		Human p56-lck tyrosine kinase sh2 domain in complex with the phosphotyrosyl peptide ac-ptyr-glu-glu-ile (pyeei peptide)		X-ray(1Å)		08-Mar-96
1lkl		×0		Human p56-lck tyrosine kinase sh2 domain in complex with the phosphotyrosyl peptide ac-ptyr-glu-glu-gly (pyeeg peptide)		X-ray(1.8Å)		08-Mar-96
1m0v		×0		Nmr structure of the type iii secretory domain of yersinia yoph complexed with the skap-hom phospho-peptide n-acetyl-depyddpf-nh2		NMR(20 models)		24-Jul-02
1m6x		×1		Flpe-holliday junction complex		X-ray(2.8Å)		04-Feb-03
1mw4		×0		Solution structure of the human grb7-sh2 domain in complex with a 10 amino acid peptide py1139		NMR(10 models)		09-Sep-03
1nh3		×0		Human topoisomerase i ara-c complex		X-ray(3.1Å)		04-Mar-03
1nzl		×0		Crystal structure of src sh2 domain bound to doubly phosphorylated peptide pqpyepyipi		X-ray(1.9Å)		22-Apr-03
1nzv		×0		Crystal structure of src sh2 domain bound to doubly phosphorylated peptide pqpyipyvpa		X-ray(2.1Å)		22-Apr-03
1o9u		×0		Glycogen synthase kinase 3 beta complexed with axin peptide		X-ray(2.4Å)		15-Aug-03
1oo4		×0		P395s mutant of the p85 regulatory subunit of the n-terminal src homology 2 domain of pi3-kinase complexed to a peptide derived from pdgfr		NMR(1 model)		25-Mar-03
1p13		×1		Crystal structure of the src sh2 domain complexed with peptide (sdpyanfk)		X-ray(1.63Å)		19-Aug-03
1p4e		×1		Flpe w330f mutant-DNA holliday junction complex		X-ray(2.7Å)		20-May-03
1p7d		×1		Crystal structure of the lambda integrase (residues 75-356) bound to DNA		X-ray(2.95Å)		12-Aug-03
1pic		×0		Phosphatidylinositol 3-kinase, p85-alpha subunit: c-terminal sh2 domain complexed with a tyr751 phosphopeptide from the pdgf receptor, nmr, minimized mean structure		NMR(1 model)		17-Sep-97
1pkg		×2		Structure of a c-kit kinase product complex		X-ray(2.9Å)		12-Aug-03
1ptt		×0		Crystal structure of protein tyrosine phosphatase 1b complexed with phosphotyrosine-containing tetra-peptide (ac-depyl-nh2)		X-ray(2.9Å)		01-Aug-96
1ptu		×0		Crystal structure of protein tyrosine phosphatase 1b complexed with phosphotyrosine-containing hexa-peptide (dadepyl-nh2)		X-ray(2.6Å)		01-Aug-96
1ptv		×0		Crystal structure of protein tyrosine phosphatase 1b complexed with phosphotyrosine		X-ray(2.3Å)		01-Aug-96
1pty		×1		Crystal structure of protein tyrosine phosphatase 1b complexed with two phosphotyrosine molecules		X-ray(1.85Å)		21-Jan-98
1qcf		×0		Crystal structure of hck in complex with a src family-selective tyrosine kinase inhibitor		X-ray(2Å)		08-Jun-99
1qg1		×0		Growth factor receptor binding protein sh2 domain complexed with an shc-derived peptide		NMR(1 model)		27-Apr-99
1qpc		×0		Structural analysis of the lymphocyte-specific kinase lck in complex with non-selective and src family selective kinase inhibitors		X-ray(1.6Å)		24-May-00
1qpd		×0		Structural analysis of the lymphocyte-specific kinase lck in complex with non-selective and src family selective kinase inhibitors		X-ray(2Å)		24-May-00
1qpe		×0		Structural analysis of the lymphocyte-specific kinase lck in complex with non-selective and src family selective kinase inhibitors		X-ray(2Å)		31-May-00
1qpj		×0		Crystal structure of the lymphocyte-specific kinase lck in complex with staurosporine.		X-ray(2.2Å)		31-May-00
1r01		×0		Molecular model of active wild type human c-kit kinase domain phosphorylated on tyr 823 and in complex with atp/2mg		Theor. model		21-Sep-04
1r1p		×3		Structural basis for differential recognition of tyrosine phosphorylated sites in the linker for activation of t cells (lat) by the adaptor protein gads		X-ray(1.8Å)		28-Sep-04
1r1q		×1		Structural basis for differential recognition of tyrosine phosphorylated sites in the linker for activation of t cells (lat) by the adaptor protein gads		X-ray(1.8Å)		28-Sep-04
1r1s		×3		Structural basis for differential recognition of tyrosine phosphorylated sites in the linker for activation of t cells (lat) by the adaptor protein gads		X-ray(1.9Å)		28-Sep-04
1rqq		×3		Crystal structure of the insulin receptor kinase in complex with the sh2 domain of aps		X-ray(2.6Å)		30-Dec-03
1rr8		×0		Structural mechanisms of camptothecin resistance by mutations in human topoisomerase i		X-ray(2.6Å)		06-Jul-04
1rrj		×0		Structural mechanisms of camptothecin resistance by mutations in human topoisomerase i		X-ray(2.3Å)		06-Jul-04
1sc7		×0		Human DNA topoisomerase i (70 kda) in complex with the indenoisoquinoline mj-ii-38 and covalent complex with a 22 base pair DNA duplex		X-ray(3Å)		19-Apr-05
1seu		×0		Human DNA topoisomerase i (70 kda) in complex with the indolocarbazole sa315f and covalent complex with a 22 base pair DNA duplex		X-ray(3Å)		19-Apr-05
1sha		×0		Crystal structure of the phosphotyrosine recognition domain sh2 of v- src complexed with tyrosine-phosphorylated peptides		X-ray(1.5Å)		31-Oct-93
1shb		×0		Crystal structure of the phosphotyrosine recognition domain sh2 of v- src complexed with tyrosine-phosphorylated peptides		X-ray(2Å)		31-Oct-93
1shc		×0		Shc ptb domain complexed with a trka receptor phosphopeptide, nmr, minimized average structure		NMR(1 model)		15-May-97
1shd		×0		Peptide inhibitors of src sh3-sh2-phosphoprotein interactions		X-ray(2Å)		26-Jan-95
1sps		×2		Binding of a high affinity phosphotyrosyl peptide to the src sh2 domain: crystal structures of the complexed and peptide-free forms		X-ray(2.7Å)		31-May-94
1t8i		×0		Human DNA topoisomerase i (70 kda) in complex with the poison camptothecin and covalent complex with a 22 base pair DNA duplex		X-ray(3Å)		31-May-05
1tce		×0		Solution nmr structure of the shc sh2 domain complexed with a tyrosine-phosphorylated peptide from the t-cell receptor, minimized average structure		NMR(1 model)		15-May-97
1tl8		×0		Human DNA topoisomerase i (70 kda) in complex with the indenoisoquinoline ai-iii-52 and covalent complex with a 22 base pair DNA duplex		X-ray(3.1Å)		21-Jun-05
1trn		×1		Crystal structure of human trypsin 1: unexpected phosphorylation of tyrosine 151		X-ray(2.2Å)		03-Jun-95
1tze		×0		Signal transduction adaptor growth factor, grb2 sh2 domain complexed with phosphotyrosyl heptapeptide lys-pro-phe-ptyr-val-asn-val-nh2 (kfppyvnc-nh2)		X-ray(2.1Å)		07-Jul-97