Ligand clusters for UniProt code P28482

Ligand clusters for P28482: Mitogen-activated protein kinase 1 from Homo sapiens

		Top 6 (of 41) ligand clusters Cluster 1. 105 ligand types 242 ligands Cluster 2. 9 ligand types 23 ligands Cluster 3. 2 ligand types 2 ligands Cluster 4. 4 ligand types 6 ligands Cluster 5. 4 ligand types 9 ligands Cluster 6. 4 ligand types 16 ligands
Representative protein: 3sa0A

Structures

PDB		Schematic diagram
3sa0A
5bvfA
5v62A
4zxtA
4fv4A
		more ...

Cluster 1 contains 105 ligand types (of which only 20 are listed. Click for all)

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
_Mg		1. Metal: _MG × 4 PDB codes: 5v60(A), 6opg(A),
		2. Ligand: DMS × 2 dimethyl sulfoxide Dimethyl sulfoxide PDB codes: 6ge0(A), 6gjd(A).
		3. Ligand: IPH × 2 phenol Phenol PDB codes: 6q7s(A),
		4. Ligand: GOL × 1 glycerin Glycerol PDB code: 5v62(A).
		5. Ligand: F29 × 1 1-Allyl-5-(2-Phenylpyrazolo[1,5-A]pyridin-3-Yl)-1h- Pyrazolo[3,4-C]pyridazin-3-Amine PDB code: 1wzy(A).
		6. Ligand: 82A × 1 (S)-N-(1-(3-Chloro-4-Fluorophenyl)-2-Hydroxyethyl)-4- (4-(3-Chlorophenyl)-1h-Pyrazol-3-Yl)-1h- Pyrrole-2- Carboxamide PDB code: 2ojj(A).
		7. Ligand: 19A × 1 N,N-Dimethyl-4-(4-Phenyl-1h-Pyrazol-3-Yl)-1h-Pyrrole- 2-Carboxamide PDB code: 2ojg(A).
		8. Ligand: 33A × 1 N-Benzyl-4-[4-(3-Chlorophenyl)-1h-Pyrazol-3-Yl]-1h- Pyrrole-2-Carboxamide PDB code: 2oji(A).
		9. Ligand: FRZ × 1 5-(2-Phenylpyrazolo[1,5-A]pyridin-3-Yl)-1h-Pyrazolo[3, 4-C]pyridazin-3-Amine PDB code: 1tvo(A).
		10. Ligand: SB2 × 1 4-[5-(4-Fluoro-Phenyl)-2-(4-Methanesulfinyl-Phenyl)- 3h-Imidazol-4-Yl]-Pyridine PDB code: 1pme(A).
		11. Ligand: SO4 × 102 Sulfate ion PDB codes: 1pme(A), 2ojg(A), 2oji(A), 2ojj(A), 3i5z(A), 3i60(A), 3sa0(A), 4fux(A), 4fuy(A), 4fv1(A), 4fv2(A), 4fv3(A), 4fv4(A), 4fv5(A), 4fv6(A), 4fv7(A), 4fv8(A), 4fv9(A), 4g6n(A), 4g6o(A), 4iz5(A), 4n0s(A), 4nif(B), 4qte(A), 4zxt(A), 4zzm(A), 4zzn(A), 4zzo(A), 5bvd(A), 5bve(A), 5bvf(A), 5lck(A), 5ngu(A), 5nhf(A), 5nhh(A), 5nhj(A), 5nhl(A), 5nho(A), 5nhp(A), 5nhv(A), 5wp1(A), 6dmg(A), 6g54(A), 6g8x(A), 6g91(A), 6g92(A), 6g93(A), 6g97(A), 6g9a(A), 6g9d(A), 6g9h(A), 6g9j(A), 6g9k(A), 6g9m(A), 6g9n(A), 6gdm(A), 6gdq(A), 6ge0(A), 6gjb(A), 6gjd(A), 6q7k(A), 6q7s(A), 6q7t(A), 6qa1(A), 6qa3(A), 6qa4(A), 6qag(A), 6qah(A), 6qal(A), 6qaq(A), 6qaw(A), 6rq4(A), 6slg(A).
		12. Ligand: EDO × 15 1,2-Ethanediol PDB codes: 4fuy(A), 4fv0(A), 4fv1(A), 4fv2(A), 4fv3(A), 4fv7(A), 4g6o(A), 4qta(A), 4qte(A), 5k4i(A), 6dmg(A), 6g54(A),
		13. Ligand: ANP × 7 Phosphoaminophosphonic acid-Adenylate ester PDB codes: 2y9q(A), 3tei(A), 4fmq(A), 4h3p(A), 4h3q(A), 4nif(B), 6opg(A).
		14. Ligand: IMD × 3 Imidazole PDB codes: 4qp1(A), 4qp2(A), 4qp6(A).
		15. Ligand: 6QB × 2 1-[(1~{s})-1-(4-Chloranyl-3-Fluoranyl-Phenyl)-2- Oxidanyl-Ethyl]-4-[2-[(2-Methylpyrazol-3- Yl) amino]pyrimidin-4-Yl]pyridin-2-One PDB codes: 5k4i(A), 6oph(A).
		16. Ligand: EK6 × 2 Ethyl n-{2-Chloro-4-[5-(5-{[(1s)-1-(3-Chloro-4- Fluorophenyl)-2-Hydroxyethyl]carbamoyl}-1h-Pyrrol- 3- Yl)-1h-Pyrazol-4-Yl]benzyl}glycinate PDB codes: 4fv3(A), 6dmg(A).
		17. Ligand: EQT × 2 4-Chloranyl-1~{h}-Indazol-3-Amine PDB codes: 6g8x(A),
		18. Ligand: HOW × 2 1,2-Oxazol-3-Amine PDB codes: 6q7t(A),
		19. Ligand: HRZ × 2 1~{h}-Pyridin-2-One PDB codes: 6qa4(A),
		20. Ligand: HUH × 2 1~{h}-1,2,3-Triazole PDB codes: 6qag(A),
+ more. Press for full list

Cluster 2 contains 9 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 3 glycerin Glycerol PDB codes: 4fv2(A), 5v60(A),
		2. Ligand: EDO × 10 1,2-Ethanediol PDB codes: 4fv0(A), 4fv3(A), 4fv7(A), 4g6o(A), 4qte(A), 6dmg(A), 6g54(A),
		3. Ligand: SO4 × 4 Sulfate ion PDB codes: 5nhh(A), 5nhp(A), 6g9m(A), 6qaq(A).
		4. Ligand: ALA-ALA-LEU-ALA-PHE × 1 PDB code: 6slg(A).
		5. Ligand: HVK × 1 Pyridin-2-Amine PDB code: 6qa1(A).
		6. Ligand: HVQ × 1 Thiophen-3-Ylmethylazanium PDB code: 6qaq(A).
		7. Ligand: KJ7 × 1 (5s)-5-Benzyl-4,5-Dihydro-1h-Imidazol-2-Amine PDB code: 6nbs(A).
		8. Ligand: PEG × 1 Di(hydroxyethyl)ether PDB code: 4n0s(A).
_Ni		9. Metal: _NI × 1 PDB code: 5bue(A).

Cluster 3 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: EDO × 1 1,2-Ethanediol PDB code: 4qte(A).
		2. Ligand: KJ4 × 1 N-{3-[(2z,4s)-1-(2-{[2-(2-Amino-1h-Imidazol-1-Yl) ethyl](methyl)amino}ethyl)-3-(3- Cyclohexylpropyl)-2- Iminoimidazolidin-4-Yl]propyl}guanidine PDB code: 6nbs(A).

Cluster 4 contains 4 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 5v61(A).
		2. Ligand: EDO × 3 1,2-Ethanediol PDB codes: 4qta(A), 4qte(A), 6g54(A).
		3. Ligand: HRZ × 1 1~{h}-Pyridin-2-One PDB code: 6qa4(A).
		4. Ligand: HVK × 1 Pyridin-2-Amine PDB code: 6qa1(A).

Cluster 5 contains 4 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 5v62(A).
		2. Ligand: EDO × 4 1,2-Ethanediol PDB codes: 4fv0(A), 4qte(A), 6slg(A).
		3. Ligand: HVK × 2 Pyridin-2-Amine PDB codes: 6qa1(A),
		4. Ligand: SO4 × 2 Sulfate ion PDB codes: 6g9d(A), 6g9n(A).

Cluster 6 contains 4 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: DMS × 4 dimethyl sulfoxide Dimethyl sulfoxide PDB codes: 4n0s(A), 6gdq(A), 6ge0(A), 6gjd(A).
		2. Ligand: GOL × 1 glycerin Glycerol PDB code: 5v60(A).
		3. Ligand: EDO × 7 1,2-Ethanediol PDB codes: 4fv0(A), 4fv1(A), 4fv2(A), 4fv3(A), 4g6o(A), 4qte(A), 6dmg(A).
		4. Ligand: SO4 × 4 Sulfate ion PDB codes: 5lcj(A), 5lck(A), 6g9h(A), 6g9n(A).