Ligand clusters for UniProt code P24300

Ligand clusters for P24300: Xylose isomerase from Streptomyces rubiginosus

		Top 6 (of 32) ligand clusters Cluster 1. 38 ligand types 234 ligands Cluster 2. 5 ligand types 19 ligands Cluster 3. 3 ligand types 16 ligands Cluster 4. 2 ligand types 9 ligands Cluster 5. 1 ligand type 1 ligand Cluster 6. 2 ligand types 4 ligands
Representative protein: 1xibA

Structures

PDB		Schematic diagram
1xibA
4xisA
3xisA
6irkA
1xisA
		more ...

Cluster 1 contains 38 ligand types (of which only 20 are listed. Click for all)

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: XYL × 2 Xylitol PDB codes: 1xig(A), 2xis(A).
		2. Ligand: XYS × 2 Alpha-D-Xylopyranose PDB codes: 3xis(A), 4xis(A).
		3. Ligand: LXC × 1 Beta-L-Xylopyranose PDB code: 1gw9(A).
_Mn		4. Metal: _MN × 73 PDB codes: 1oad(A), 1xib(A), 1xic(A), 1xid(A), 1xie(A), 1xif(A), 1xig(A), 1xih(A), 1xii(A), 1xij(A), 1xis(A), 2glk(A), 3gnx(A), 3n4a(A), 4e3v(A), 4lnc(A), 4xis(A), 4zb0(A), 4zb2(A), 4zb5(A), 4zbc(A), 5avn(A), 5vr0(A), 5zyc(A), 5zye(A), 6oqz(A), 6qrr(A), 6qrs(A), 6qrt(A), 6qru(A), 6qrv(A), 6qrw(A), 6qrx(A), 6qry(A), 6quf(A), 6quk(A), 6vrs(A), 8xia(A), 9xia(A),
_Mg		5. Metal: _MG × 45 PDB codes: 1mnz(A), 1o1h(A), 1oad(A), 2g4j(A), 3kbw(A), 3u3h(A), 4e3v(A), 4us6(A), 5y4i(A), 5zyd(A), 6irk(A), 6kca(A), 6kcc(A), 6kd2(A), 6ll2(A), 6oqz(A), 6qnh(A), 6qrr(A), 6qrs(A), 6qrt(A), 6qru(A), 6qrv(A), 6qrw(A), 6qrx(A), 6qry(A), 6ybo(A), 6ybr(A), 7bvl(A), 7bvn(A), 7ck0(A), 7cvk(A), 7cvm(A),
		6. Ligand: GLC × 14 d-glucose Alpha-D-Glucopyranose PDB codes: 1xif(A), 3kbm(A), 3kcl(A), 4lnc(A), 4zb0(A), 4zb2(A), 4zb5(A), 4zbc(A), 5zye(A), 6qnc(A), 6qni(A), 6qnj(A), 6rnd(A), 6rnf(A).
		7. Ligand: GOL × 10 glycerin Glycerol PDB codes: 2glk(A), 4a8n(A), 4a8r(A), 4us6(A), 5y4i(A), 6quf(A), 6quk(A),
		8. Ligand: SOR × 2 sorbitol Sorbitol PDB codes: 1xih(A), 4dvo(A).
		9. Ligand: TRS × 2 tromethamine 2-Amino-2-Hydroxymethyl-Propane-1,3-Diol PDB codes: 1mnz(A), 1o1h(A).
_Zn		10. Metal: _ZN × 2 PDB codes: 4j4k(A),
		11. Ligand: ASC × 1 ascorbic acid Ascorbic acid PDB code: 1xid(A).
		12. Ligand: FRU × 1 fructose Beta-D-Fructofuranose PDB code: 4zbc(A).
		13. Ligand: ASO × 1 1,5-Anhydro-D-Glucitol PDB code: 1xie(A).
		14. Ligand: DFR × 1 3-Deoxy-3-Methyl-Beta-D-Fructofuranose PDB code: 9xia(A).
		15. Ligand: XLS × 4 D-Xylose PDB codes: 1xic(A), 3xis(A), 4xis(A), 8xia(A).
		16. Ligand: XUL × 1 D-Xylulose PDB code: 1xii(A).
		17. Ligand: THE × 1 Threonate ion PDB code: 1xij(A).
		18. Ligand: MPD × 1 (4s)-2-Methyl-2,4-Pentanediol PDB code: 1o1h(A).
		19. Ligand: MRD × 1 (4r)-2-Methylpentane-2,4-Diol PDB code: 1mnz(A).
		20. Ligand: EDO × 19 1,2-Ethanediol PDB codes: 4a8i(A), 4a8l(A), 5zyc(A), 6qrr(A), 6qrs(A), 6qrt(A), 6qru(A), 6qrv(A), 6qrw(A), 6qrx(A), 6qry(A),
+ more. Press for full list

Cluster 2 contains 5 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: FRU × 1 fructose Beta-D-Fructofuranose PDB code: 4zb2(A).
		2. Ligand: GLC × 1 d-glucose Alpha-D-Glucopyranose PDB code: 4zbc(A).
_Mn		3. Metal: _MN × 1 PDB code: 4zbc(A).
		4. Ligand: EDO × 8 1,2-Ethanediol PDB codes: 6qrr(A), 6qrs(A), 6qrt(A), 6qru(A), 6qrv(A), 6qrw(A), 6qrx(A), 6qry(A).
_Na		5. Metal: _NA × 8 PDB codes: 6qrr(A), 6qrs(A), 6qrt(A), 6qru(A), 6qrv(A), 6qrw(A), 6qrx(A), 6qry(A).

Cluster 3 contains 3 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 6 glycerin Glycerol PDB codes: 2glk(A), 4a8n(A), 4a8r(A), 4us6(A), 6quf(A), 6quk(A).
		2. Ligand: FRU × 2 fructose Beta-D-Fructofuranose PDB codes: 4zb0(A), 4zbc(A).
		3. Ligand: EDO × 8 1,2-Ethanediol PDB codes: 6qrr(A), 6qrs(A), 6qrt(A), 6qru(A), 6qrv(A), 6qrw(A), 6qrx(A), 6qry(A).

Cluster 4 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: EDO × 8 1,2-Ethanediol PDB codes: 6qrr(A), 6qrs(A), 6qrt(A), 6qru(A), 6qrv(A), 6qrw(A), 6qrx(A), 6qry(A).
		2. Ligand: PRO × 1 PDB code: 4e3v(A).

Cluster 5 contains 1 ligand type

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: FRU × 1 fructose Beta-D-Fructofuranose PDB code: 4zb0(A).

Cluster 6 contains 2 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 6quk(A).
		2. Ligand: SO4 × 3 Sulfate ion PDB codes: 4e3v(A), 5avn(A), 6quf(A).