Ligand clusters for UniProt code P05979

Ligand clusters for P05979: Prostaglandin G/H synthase 1 from Ovis aries

		Top 6 (of 10) ligand clusters Cluster 1. 10 ligand types 26 ligands Cluster 2. 21 ligand types 60 ligands Cluster 3. 7 ligand types 18 ligands Cluster 4. 6 ligand types 24 ligands Cluster 5. 6 ligand types 28 ligands Cluster 6. 4 ligand types 30 ligands
Representative protein: 1prhA

Structures

PDB		Schematic diagram
1prhA
1eqhA
1ht8A
2oyuP
2oyeP
		more ...

Cluster 1 contains 10 ligand types

Use checkboxes to select ligands to display in RasMol, Jmol, or download as an SDF file. Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: NAG × 5 n-acetylglucosamine 2-Acetamido-2-Deoxy-Beta-D-Glucopyranose PDB codes: 1eqg(A), 1eqh(A), 1ht5(A), 1ht8(A),
		2. Ligand: BOG × 1 Octyl beta-D-Glucopyranoside PDB code: 1u67(A).
		3. Ligand: NAG-NAG × 6 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose. PDB codes: 1cqe(A), 1djj(A), 1ebv(A), 1pth(A), 3n8z(A), 4o1z(A).
		4. Ligand: NAG-NAG-BMA-BMA-MAN × 3 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose, MAN=Alpha-D-Mannopyranose. PDB codes: 1diy(A), 1igx(A), 1igz(A).
		5. Ligand: NAG-NAG-MAN-MAN-MAN × 3 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, MAN=Alpha-D-Mannopyranose. PDB codes: 2ayl(A), 5u6x(A), 5wbe(A).
		6. Ligand: NAG-NDG-BMA-MAN-MAN × 3 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, NDG=2-Acetamido-2-Deoxy-Alpha-D-Glucopyranose, BMA=Beta-D-Mannopyranose, MAN=Alpha-D-Mannopyranose. PDB codes: 3n8v(A), 3n8w(A), 3n8y(A).
		7. Ligand: NAG-NAG-BMA-BMA × 2 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose. PDB codes: 1u67(A), 2oye(P).
		8. Ligand: NAG-NAG-BMA × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose. PDB code: 2oyu(P).
		9. Ligand: NAG-NAG-BMA-BMA-BMA × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose. PDB code: 3n8x(A).
		10. Ligand: NAG-NAG-MAN-BMA-MAN × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, MAN=Alpha-D-Mannopyranose, BMA=Beta-D-Mannopyranose. PDB code: 3kk6(A).

Cluster 2 contains 21 ligand types (of which only 20 are listed. Click for all)

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: ACD × 2 Arachidonic acid PDB codes: 1diy(A), 1u67(A).
		2. Ligand: FLP × 5 flurbiprofen Flurbiprofen PDB codes: 1cqe(A), 1eqh(A), 2ayl(A), 3n8w(A), 3n8z(A).
		3. Ligand: CEL × 1 celecoxib 4-[5-(4-Methylphenyl)-3-(Trifluoromethyl)-1h-Pyrazol-1- Yl]benzenesulfonamide PDB code: 3kk6(A).
		4. Ligand: DIF × 1 diclofenac 2-[2,6-Dichlorophenyl)amino]benzeneacetic acid PDB code: 3n8y(A).
		5. Ligand: EIC × 1 linoleic acid Linoleic acid PDB code: 1igz(A).
		6. Ligand: EPA × 1 icosapent 5,8,11,14,17-Eicosapentaenoic acid PDB code: 1igx(A).
		7. Ligand: IBP × 1 dexibuprofen Ibuprofen PDB code: 1eqg(A).
		8. Ligand: MXM × 1 meloxicam 4-Hydroxy-2-Methyl-N-(5-Methyl-1,3-Thiazol-2-Yl)-2h-1, 2-Benzothiazine-3-Carboxamide 1,1-Dioxide PDB code: 4o1z(A).
		9. Ligand: NIM × 1 nimesulide 4-Nitro-2-Phenoxymethanesulfonanilide PDB code: 3n8x(A).
		10. Ligand: SAL × 1 salicylic acid 2-Hydroxybenzoic acid PDB code: 1pth(A).
		11. Ligand: BOG × 17 Octyl beta-D-Glucopyranoside PDB codes: 1cqe(A), 1diy(A), 1eqg(A), 1eqh(A), 1ht5(A), 1ht8(A), 1igz(A), 1pth(A), 1u67(A), 2ayl(A),
		12. Ligand: 34C × 1 (3-Chloro-4-Propoxy-Phenyl)-Acetic acid PDB code: 1ht8(A).
		13. Ligand: FL2 × 1 Flurbiprofen methyl ester PDB code: 1ht5(A).
		14. Ligand: SCL × 1 Acetic acid salicyloyl-Amino-Ester PDB code: 1ebv(A).
		15. Ligand: BOG × 18 B-Octylglucoside PDB codes: 1djj(A), 1igx(A), 2oye(P), 2oyu(P), 3kk6(A), 3n8v(A), 3n8w(A), 3n8y(A), 3n8z(A), 5u6x(A), 5wbe(A).
		16. Ligand: BGC × 2 Beta-D-Glucopyranose PDB codes: 1igx(A), 1igz(A).
		17. Ligand: 63X × 1 Mofezolac PDB code: 5wbe(A).
		18. Ligand: IM8 × 1 2-[1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-1h-Indol-3- Yl]-N-[(1r)-1-(Hydroxymethyl)propyl]acetamide PDB code: 2oye(P).
		19. Ligand: IMS × 1 2-[1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-1h-Indol-3- Yl]-N-[(1s)-1-(Hydroxymethyl)propyl]acetamide PDB code: 2oyu(P).
		20. Ligand: NSA × 1 2,2-Dichloro-N-Phenyl-Acetamide PDB code: 1djj(A).
+ more. Press for full list

Cluster 3 contains 7 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: NAG × 6 n-acetylglucosamine 2-Acetamido-2-Deoxy-Beta-D-Glucopyranose PDB codes: 1eqg(A), 1eqh(A), 1ht5(A), 1ht8(A).
		2. Ligand: NAG-NAG × 4 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose. PDB codes: 1cqe(A), 1pth(A), 3n8x(A), 4o1z(A).
		3. Ligand: NAG-NAG-MAN-MAN-MAN × 3 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, MAN=Alpha-D-Mannopyranose. PDB codes: 2ayl(A), 5u6x(A), 5wbe(A).
		4. Ligand: NAG-NDG-BMA-BMA × 2 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, NDG=2-Acetamido-2-Deoxy-Alpha-D-Glucopyranose, BMA=Beta-D-Mannopyranose. PDB codes: 3n8v(A), 3n8y(A).
		5. Ligand: NAG-NAG-BMA-BMA-MAN × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose, MAN=Alpha-D-Mannopyranose. PDB code: 3n8z(A).
		6. Ligand: NAG-NAG-MAN-BMA × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, MAN=Alpha-D-Mannopyranose, BMA=Beta-D-Mannopyranose. PDB code: 3kk6(A).
		7. Ligand: NAG-NDG-BMA × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, NDG=2-Acetamido-2-Deoxy-Alpha-D-Glucopyranose, BMA=Beta-D-Mannopyranose. PDB code: 3n8w(A).

Cluster 4 contains 6 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: NAG × 8 n-acetylglucosamine N-Acetyl-D-Glucosamine PDB codes: 1djj(A), 1ebv(A), 1eqg(A), 1eqh(A), 1ht5(A), 1ht8(A), 1pth(A), 3n8x(A).
		2. Ligand: NAG-NAG × 11 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose. PDB codes: 1cqe(A), 1diy(A), 1igx(A), 1igz(A), 2oye(P), 2oyu(P), 3n8v(A), 3n8z(A), 4o1z(A), 5u6x(A), 5wbe(A).
		3. Ligand: NAG-NDG × 2 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, NDG=2-Acetamido-2-Deoxy-Alpha-D-Glucopyranose. PDB codes: 1u67(A), 3kk6(A).
		4. Ligand: NAG-NAG-BMA × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose. PDB code: 3n8w(A).
		5. Ligand: NAG-NAG-BMA-BMA × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, BMA=Beta-D-Mannopyranose. PDB code: 3n8y(A).
		6. Ligand: NAG-NAG-MAN-MAN × 1 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, MAN=Alpha-D-Mannopyranose. PDB code: 2ayl(A).

Cluster 5 contains 6 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: GOL × 1 glycerin Glycerol PDB code: 2ayl(A).
		2. Ligand: HEM × 8 Protoporphyrin IX containing fe PDB codes: 1cqe(A), 1ebv(A), 1eqg(A), 1eqh(A), 1ht5(A), 1ht8(A), 1prh(A), 1pth(A).
		3. Ligand: COH × 4 Protoporphyrin IX containing co PDB codes: 1diy(A), 1igx(A), 1igz(A), 1u67(A).
		4. Ligand: MNH × 1 Manganese protoporphyrin IX PDB code: 2ayl(A).
		5. Ligand: HEM × 12 Protoporphyrin IX containing fe PDB codes: 1djj(A), 2oye(P), 2oyu(P), 3kk6(A), 3n8v(A), 3n8w(A), 3n8x(A), 3n8y(A), 3n8z(A), 4o1z(A), 5u6x(A), 5wbe(A).
		6. Ligand: FLC × 2 Citrate anion PDB codes: 2oye(P), 3kk6(A).

Cluster 6 contains 4 ligand types

Selection shortcuts: select all/none invert selection.
Ligand		Description
		1. Ligand: NAG × 11 n-acetylglucosamine N-Acetyl-D-Glucosamine PDB codes: 1djj(A), 1ebv(A), 1eqg(A), 1eqh(A), 1ht5(A), 1ht8(A), 1pth(A), 4o1z(A).
		2. Ligand: BOG × 5 Octyl beta-D-Glucopyranoside PDB codes: 1cqe(A), 1eqg(A), 1eqh(A), 1ht8(A), 2ayl(A).
		3. Ligand: NAG-NDG × 8 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose, NDG=2-Acetamido-2-Deoxy-Alpha-D-Glucopyranose. PDB codes: 1diy(A), 1igx(A), 1igz(A), 1u67(A), 2oye(P), 3n8v(A), 3n8w(A), 3n8z(A).
		4. Ligand: NAG-NAG × 6 NAG=2-Acetamido-2-Deoxy-Beta-D-Glucopyranose. PDB codes: 1cqe(A), 2ayl(A), 2oyu(P), 3n8x(A), 5u6x(A), 5wbe(A).