Ligand clusters for UniProt code P00378

Ligand clusters for P00378: Dihydrofolate reductase OS=Gallus gallus GN=DHFR PE=1 SV=1

		2 ligand clusters Cluster 1. 5 ligand types 20 ligands Cluster 2. 2 ligand types 4 ligands
Representative protein: 1dr1A

Structures

PDB		Schematic diagram
1dr1A
8dfrA
1dr3A
1dr6A
1dr7A
		more ...

Cluster 1 contains 5 ligand types

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Ligand		Description
		1. Ligand: NAP × 5 Nadp nicotinamide-Adenine-Dinucleotide phosphate PDB codes: 1dr1(A), 1dr4(A), 1dr5(A), 1dr6(A), 1dr7(A).
		2. Ligand: NDP × 1 Nadph dihydro-Nicotinamide-Adenine-Dinucleotide phosphate PDB code: 8dfr(A).
		3. Ligand: TAP × 2 7-Thionicotinamide-Adenine-Dinucleotide phosphate PDB codes: 1dr2(A), 1dr3(A).
		4. Ligand: HBI × 4 7,8-Dihydrobiopterin PDB codes: 1dr1(A), 1dr3(A), 1dr4(A), 1dr6(A).
_Ca		5. Metal: _CA × 8 PDB codes: 1dr1(A), 1dr2(A), 1dr3(A), 1dr4(A), 1dr5(A), 1dr6(A), 1dr7(A), 8dfr(A).

Cluster 2 contains 2 ligand types

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Ligand		Description
		1. Ligand: MBO × 2 Mercuribenzoic acid PDB codes: 1dr6(A), 1dr7(A).
_Hg		2. Metal: _HG × 2 PDB codes: 1dr4(A), 1dr5(A).