PDBsum entry 6pas

Signaling protein

PDB id: 6pas

Contents

Protein chains

559 a.a.

576 a.a.

Ligands

HEM

PDB id:

6pas

Name:

Signaling protein

Title:

Inactive state of manduca sexta soluble guanylate cyclase

Structure:

Soluble guanylyl cyclase alpha-1 subunit. Chain: a. Engineered: yes. Soluble guanylyl cyclase beta-1 subunit. Chain: b. Engineered: yes

Source:

Manduca sexta. Tobacco hawkmoth. Organism_taxid: 7130. Expressed in: spodoptera aff. Frugiperda 2 rz-2014. Expression_system_taxid: 1491790. Expression_system_taxid: 1491790

Authors:

A.L.Yokom,B.G.Horst,M.A.Marletta,J.H.Hurley

Key ref:

B.G.Horst et al. (2019). Allosteric activation of the nitric oxide receptor so guanylate cyclase mapped by cryo-Electron microscopy.. Elife, 8, . PubMed id: 31566566

Date:

11-Jun-19 Release date: 23-Oct-19

Protein chain

O77105  (O77105_MANSE) -  guanylate cyclase from Manduca sexta

Seq: 699 a.a.

Struc: 559 a.a.

Protein chain

O77106  (O77106_MANSE) -  Guanylate cyclase soluble subunit beta-1 from Manduca sexta

Seq: 600 a.a.

Struc: 576 a.a.

Enzyme reactions

• Enzyme class: Chains A, B: E.C.4.6.1.2 - guanylate cyclase.
• Reaction: GTP = 3',5'-cyclic GMP + diphosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site