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PDBsum entry 3ogd
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Hydrolase/DNA
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PDB id
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3ogd
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Hydrolase/DNA
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Title:
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Alka undamaged DNA complex: interrogation of a g :C base pair
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Structure:
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DNA-3-methyladenine glycosylase 2. Chain: a. Synonym: DNA-3-methyladenine glycosylase ii, 3-methyladenine-DNA glycosylase ii, inducible, tag ii, DNA-3-methyladenine glycosidase ii. Engineered: yes. Mutation: yes. 5'-d( Gp Cp Ap Gp Tp Cp Ap Tp G)-3'. Chain: b.
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Source:
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Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: aida, alka, b2068, jw2053. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic: yes
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Resolution:
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2.80Å
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R-factor:
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0.218
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R-free:
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0.269
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Authors:
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B.R.Bowman,S.Lee,S.Wang,G.L.Verdine
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Key ref:
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B.R.Bowman
et al.
(2010).
Structure of Escherichia coli AlkA in complex with undamaged DNA.
J Biol Chem,
285,
35783-35791.
PubMed id:
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Date:
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16-Aug-10
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Release date:
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15-Sep-10
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PROCHECK
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Headers
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References
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P04395
(3MG2_ECOLI) -
DNA-3-methyladenine glycosylase 2 from Escherichia coli (strain K12)
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Seq:
Struc:
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282 a.a.
288 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 2 residue positions (black
crosses)
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G-C-A-G-T-C-A-T-G
9 bases
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C-A-BRU-G-A-C-BRU-G-C
9 bases
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Enzyme class:
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E.C.3.2.2.21
- DNA-3-methyladenine glycosylase Ii.
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Reaction:
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Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine, and 7-methyladenine.
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J Biol Chem
285:35783-35791
(2010)
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PubMed id:
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Structure of Escherichia coli AlkA in complex with undamaged DNA.
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B.R.Bowman,
S.Lee,
S.Wang,
G.L.Verdine.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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C.Yi,
B.Chen,
B.Qi,
W.Zhang,
G.Jia,
L.Zhang,
C.J.Li,
A.R.Dinner,
C.G.Yang,
and
C.He
(2012).
Duplex interrogation by a direct DNA repair protein in search of base damage.
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Nat Struct Mol Biol,
19,
671-676.
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PDB codes:
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
codes are
shown on the right.
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Links
