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PDBsum entry 2ywc
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Contents |
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* Residue conservation analysis
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PDB id:
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Ligase
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Title:
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Crystal structure of gmp synthetase from thermus thermophilus in complex with xmp
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Structure:
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Gmp synthase [glutamine-hydrolyzing]. Chain: a, b, c, d. Synonym: glutamine amidotransferase, gmp synthetase. Engineered: yes
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Source:
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Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Gene: guaa. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.20Å
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R-factor:
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0.236
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R-free:
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0.278
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Authors:
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S.Baba,M.Kanagawa,S.Kuramitsu,S.Yokoyama,G.Sampei,G.Kawai,Riken Structural Genomics/proteomics Initiative (Rsgi)
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Key ref:
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S.Baba
et al.
Crystal structure of gmp synthetase from thermus thermophilus.
To be published,
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Date:
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20-Apr-07
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Release date:
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23-Oct-07
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PROCHECK
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Headers
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References
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Q5SI28
(GUAA_THET8) -
GMP synthase [glutamine-hydrolyzing] from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
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Seq:
Struc:
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503 a.a.
475 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.6.3.5.2
- Gmp synthase (glutamine-hydrolyzing).
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Pathway:
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AMP and GMP Biosynthesis
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Reaction:
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XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H+
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XMP
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+
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L-glutamine
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+
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ATP
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+
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H2O
Bound ligand (Het Group name = )
corresponds exactly
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=
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GMP
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+
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L-glutamate
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+
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AMP
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+
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diphosphate
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+
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2
×
H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
