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UniProt functional annotation for Q5SI28 | ||
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| UniProt code: Q5SI28. |
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| Organism: | |
Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8). |
| Taxonomy: | |
Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus. |
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| Function: | |
Catalyzes the synthesis of GMP from XMP. {ECO:0000255|HAMAP- Rule:MF_00344}. |
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| Catalytic activity: | |
Reaction=ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate; Xref=Rhea:RHEA:11680, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57464, ChEBI:CHEBI:58115, ChEBI:CHEBI:58359, ChEBI:CHEBI:456215; EC=6.3.5.2; Evidence={ECO:0000255|HAMAP-Rule:MF_00344}; |
| Pathway: | |
Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1. {ECO:0000255|HAMAP-Rule:MF_00344}. |
| Subunit: | |
Homodimer. {ECO:0000255|HAMAP-Rule:MF_00344}. |
Annotations taken from UniProtKB at the EBI.