PDBsum entry 1vlo

Transferase

PDB id

1vlo

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Contents

			Protein chain

					364 a.a. *

			Waters ×419

* Residue conservation analysis

PDB id:

1vlo

Links

Name:

Transferase

Title:

Crystal structure of aminomethyltransferase (t protein; tetrahydrofolate-dependent) of glycine cleavage system (np417381) from escherichia coli k12 at 1.70 a resolution

Structure:

Aminomethyltransferase. Chain: a. Synonym: glycine cleavage system t protein. Engineered: yes. Mutation: yes. Other_details: t protein, tetrahydrofolate-dependent

Source:

Escherichia coli k12. Organism_taxid: 83333. Strain: k12. Gene: gcvt. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.70Å

R-factor:

0.161

R-free:

0.195

Authors:

Joint Center For Structural Genomics (Jcsg)

Key ref:

Joint center for structural genomics (jcsg) Crystal structure of aminomethyltransferase (t protein. To be published, .

Date:

05-Aug-04

Release date:

21-Sep-04

PROCHECK

	Headers

	References

Protein chain

P27248 (GCST_ECOLI) - Aminomethyltransferase from Escherichia coli (strain K12)

Seq: Struc:					364 a.a. 364 a.a.

Key:

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.2.1.2.10 - aminomethyltransferase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Pathway:

Glycine Cleavage System

Reaction:

N₆-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein] + (6S)- 5,6,7,8-tetrahydrofolate = N₆-[(R)-dihydrolipoyl]-L-lysyl-[protein] + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NH4⁺

[Protein]-S(8)-aminomethyldihydrolipoyllysine	+	tetrahydrofolate	=	[protein]-dihydrolipoyllysine	+	5,10-methylenetetrahydrofolate	+	NH(3)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site