PDBsum entry 1th3

Oxidoreductase

PDB id: 1th3

Contents

Protein chains

499 a.a. *

Ligands

CYN-HEM ×2

HEM ×2

Waters ×688

* Residue conservation analysis

PDB id:

1th3

Name:

Oxidoreductase

Title:

Crystal structure of NADPH depleted bovine live catalase complexed with cyanide

Structure:

Catalase. Chain: a, b, c, d. Ec: 1.11.1.6

Source:

Bos taurus. Cattle. Organism_taxid: 9913. Organ: liver

Biol. unit:

Tetramer (from PQS)

Resolution:

2.80Å R-factor: 0.198 R-free: 0.261

Authors:

R.Sugadev,D.Balasundaresan,M.N.Ponnuswamy,D.Kumaran,S.Swaminathan, K.Sekar

Key ref:

R.Sugadev et al. The crystal structure of bovine liver catalase. To be published, .

Date:

01-Jun-04 Release date: 05-Jul-05

Protein chains

P00432  (CATA_BOVIN) -  Catalase from Bos taurus

Seq: 527 a.a.

Struc: 499 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.1.11.1.6 - catalase.
• Reaction: 2 H2O2 = O2 + 2 H2O
• Cofactor: Heme; Mn(2+)

Heme (Bound ligand (Het Group name = HEM) matches with 95.45% similarity) Mn(2+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site