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UniProt functional annotation for P00432 | ||
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| UniProt code: P00432. |
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| Organism: | |
Bos taurus (Bovine). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos. |
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| Function: | |
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells. |
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| Catalytic activity: | |
Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU10013, ECO:0000269|PubMed:10691967}; |
| Cofactor: | |
Name=heme; Xref=ChEBI:CHEBI:30413; |
| Cofactor: | |
Name=NADP(+); Xref=ChEBI:CHEBI:58349; |
| Biophysicochemical properties: | |
pH dependence: Optimum pH is 7. {ECO:0000269|PubMed:10691967}; |
| Subunit: | |
Homotetramer. |
| Subcellular location: | |
Peroxisome. |
| Similarity: | |
Belongs to the catalase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.