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PDBsum entry 1pec
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Lyase(acting on polysaccharides) PDB id
1pec
Contents
Protein chain
352 a.a.*
* C-alpha coords only
Superseded by: 2pec
PDB id:
1pec
Name: Lyase(acting on polysaccharides)
Structure: Pectate lyasE C (plc)
Source: (Erwinia chrysanthemi ec16) expressed in (escherichia coli)
Authors: M.D.Yoder,N.T.Keen,F.Jurnak
Key ref: M.D.Yoder et al. (1993). New domain motif: the structure of pectate lyase C, a secreted plant virulence factor. Science, 260, 1503-1507. PubMed id: 8502994 DOI: 10.1126/science.8502994
Date:
06-Apr-93     Release date:   15-Jul-93    
 Headers
 References

Protein chain
No UniProt id for this chain
Struc: 352 a.a.
Key:    Secondary structure

 

 
    Key reference    
 
 
DOI no: 10.1126/science.8502994 Science 260:1503-1507 (1993)
PubMed id: 8502994  
 
 
New domain motif: the structure of pectate lyase C, a secreted plant virulence factor.
M.D.Yoder, N.T.Keen, F.Jurnak.
 
  ABSTRACT  
 
Pectate lyases are secreted by pathogens and initiate soft-rot diseases in plants by cleaving polygalacturonate, a major component of the plant cell wall. The three-dimensional structure of pectate lyase C from Erwinia chrysanthemi has been solved and refined to a resolution of 2.2 angstroms. The enzyme folds into a unique motif of parallel beta strands coiled into a large helix. Within the core, the amino acids form linear stacks and include a novel asparagine ladder. The sequence similarities that pectate lyases share with pectin lyases, pollen and style proteins, and tubulins suggest that the parallel beta helix motif may occur in a broad spectrum of proteins.
 

Literature references that cite this PDB file's key reference

  PubMed id Reference
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In silico characterization of pectate lyase protein sequences from different source organisms.
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20070870 D.Verma, A.Kanagaraj, S.Jin, N.D.Singh, P.E.Kolattukudy, and H.Daniell (2010).
Chloroplast-derived enzyme cocktails hydrolyse lignocellulosic biomass and release fermentable sugars.
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The essential role of GhPEL gene, encoding a pectate lyase, in cell wall loosening by depolymerization of the de-esterified pectin during fiber elongation in cotton.
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UpaH is a newly identified autotransporter protein that contributes to biofilm formation and bladder colonization by uropathogenic Escherichia coli CFT073.
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20805221 M.L.Garron, and M.Cygler (2010).
Structural and mechanistic classification of uronic acid-containing polysaccharide lyases.
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19916917 P.K.Yadav, V.K.Singh, S.Yadav, K.D.Yadav, and D.Yadav (2009).
In silico analysis of pectin lyase and pectinase sequences.
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Active-site gating regulates substrate selectivity in a chymotrypsin-like serine protease the structure of haemophilus influenzae immunoglobulin A1 protease.
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PDB code: 3h09
19432536 Y.Liu, J.Carbonell, V.Gopalakrishnan, and P.Weigele (2009).
Conditional graphical models for protein structural motif recognition.
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18339938 C.Wasmer, A.Lange, H.Van Melckebeke, A.B.Siemer, R.Riek, and B.H.Meier (2008).
Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core.
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PDB code: 2rnm
18535148 D.W.Abbott, and A.B.Boraston (2008).
Structural biology of pectin degradation by Enterobacteriaceae.
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18462681 J.J.Müller, S.Barbirz, K.Heinle, A.Freiberg, R.Seckler, and U.Heinemann (2008).
An intersubunit active site between supercoiled parallel beta helices in the trimeric tailspike endorhamnosidase of Shigella flexneri Phage Sf6.
  Structure, 16, 766-775.
PDB codes: 2vbe 2vbk 2vbm
18256495 K.Murata, S.Kawai, B.Mikami, and W.Hashimoto (2008).
Superchannel of bacteria: biological significance and new horizons.
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17932919 M.A.Ciardiello, R.D'Avino, A.Amoresano, L.Tuppo, A.Carpentieri, V.Carratore, M.Tamburrini, A.Giovane, P.Pucci, and L.Camardella (2008).
The peculiar structural features of kiwi fruit pectin methylesterase: amino acid sequence, oligosaccharides structure, and modeling of the interaction with its natural proteinaceous inhibitor.
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18433454 P.G.Leiman, and I.J.Molineux (2008).
Evolution of a new enzyme activity from the same motif fold.
  Mol Microbiol, 69, 287-290.  
18214954 Q.R.Fan, and W.A.Hendrickson (2008).
Comparative structural analysis of the binding domain of follicle stimulating hormone receptor.
  Proteins, 72, 393-401.  
18156340 Z.Xiao, H.Bergeron, S.Grosse, M.Beauchemin, M.L.Garron, D.Shaya, T.Sulea, M.Cygler, and P.C.Lau (2008).
Improvement of the thermostability and activity of a pectate lyase by single amino acid substitutions, using a strategy based on melting-temperature-guided sequence alignment.
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PDB codes: 2qx3 2qxz 2qy1
17459000 A.Collmer, S.Gold, and N.T.Keen (2007).
Noel T. Keen--pioneer leader in molecular plant pathology.
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17478502 C.X.Weichenberger, and M.J.Sippl (2007).
NQ-Flipper: recognition and correction of erroneous asparagine and glutamine side-chain rotamers in protein structures.
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16765889 C.X.Weichenberger, and M.J.Sippl (2006).
Self-consistent assignment of asparagine and glutamine amide rotamers in protein crystal structures.
  Structure, 14, 967-972.  
16550377 G.Michel, P.Nyval-Collen, T.Barbeyron, M.Czjzek, and W.Helbert (2006).
Bioconversion of red seaweed galactans: a focus on bacterial agarases and carrageenases.
  Appl Microbiol Biotechnol, 71, 23-33.  
17075135 G.W.Buchko, S.Ni, H.Robinson, E.A.Welsh, H.B.Pakrasi, and M.A.Kennedy (2006).
Characterization of two potentially universal turn motifs that shape the repeated five-residues fold--crystal structure of a lumenal pentapeptide repeat protein from Cyanothece 51142.
  Protein Sci, 15, 2579-2595.
PDB codes: 2f3l 2g0y
16531237 P.Iengar, N.V.Joshi, and P.Balaram (2006).
Conformational and sequence signatures in beta helix proteins.
  Structure, 14, 529-542.  
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Hyaluronidases: their genomics, structures, and mechanisms of action.
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17001597 S.Chowdhury, G.Schatte, and H.B.Kraatz (2006).
Rational design of bioorganometallic foldamers: a potential model for parallel beta-helical peptides.
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16597248 Y.Liu, J.Carbonell, P.Weigele, and V.Gopalakrishnan (2006).
Protein fold recognition using segmentation conditional random fields (SCRFs).
  J Comput Biol, 13, 394-406.  
15539389 E.W.Czerwinski, T.Midoro-Horiuti, M.A.White, E.G.Brooks, and R.M.Goldblum (2005).
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  J Biol Chem, 280, 3740-3746.
PDB code: 1pxz
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Structure of a group A streptococcal phage-encoded virulence factor reveals a catalytically active triple-stranded beta-helix.
  Proc Natl Acad Sci U S A, 102, 17652-17657.
PDB code: 2c3f
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Structures for amyloid fibrils.
  FEBS J, 272, 5950-5961.  
15968068 S.A.Douthit, M.Dlakic, D.E.Ohman, and M.J.Franklin (2005).
Epimerase active domain of Pseudomonas aeruginosa AlgG, a protein that contains a right-handed beta-helix.
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16533927 S.C.Meredith (2005).
Protein denaturation and aggregation: Cellular responses to denatured and aggregated proteins.
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15143215 A.V.Kajava, U.Baxa, R.B.Wickner, and A.C.Steven (2004).
A model for Ure2p prion filaments and other amyloids: the parallel superpleated beta-structure.
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15079085 B.Clantin, H.Hodak, E.Willery, C.Locht, F.Jacob-Dubuisson, and V.Villeret (2004).
The crystal structure of filamentous hemagglutinin secretion domain and its implications for the two-partner secretion pathway.
  Proc Natl Acad Sci U S A, 101, 6194-6199.
PDB code: 1rwr
14695285 D.J.Gordon, J.J.Balbach, R.Tycko, and S.C.Meredith (2004).
Increasing the amphiphilicity of an amyloidogenic peptide changes the beta-sheet structure in the fibrils from antiparallel to parallel.
  Biophys J, 86, 428-434.  
15159558 H.Novoa De Armas, C.Verboven, C.De Ranter, J.Desair, A.Vande Broek, J.Vanderleyden, and A.Rabijns (2004).
Azospirillum irakense pectate lyase displays a toroidal fold.
  Acta Crystallogr D Biol Crystallogr, 60, 999.
PDB code: 1r76
15267573 M.Bachmann, and W.Janke (2004).
Thermodynamics of lattice heteropolymers.
  J Chem Phys, 120, 6779-6791.  
15102455 R.Tycko (2004).
Progress towards a molecular-level structural understanding of amyloid fibrils.
  Curr Opin Struct Biol, 14, 96.  
15322277 S.Betts, C.Haase-Pettingell, K.Cook, and J.King (2004).
Buried hydrophobic side-chains essential for the folding of the parallel beta-helix domains of the P22 tailspike.
  Protein Sci, 13, 2291-2303.  
15291806 S.P.Graether, and B.D.Sykes (2004).
Cold survival in freeze-intolerant insects: the structure and function of beta-helical antifreeze proteins.
  Eur J Biochem, 271, 3285-3296.  
  16233728 W.Hashimoto, M.Yamasaki, T.Itoh, K.Momma, B.Mikami, and K.Murata (2004).
Super-channel in bacteria: structural and functional aspects of a novel biosystem for the import and depolymerization of macromolecules.
  J Biosci Bioeng, 98, 399-413.  
12904578 A.Di Matteo, L.Federici, B.Mattei, G.Salvi, K.A.Johnson, C.Savino, G.De Lorenzo, D.Tsernoglou, and F.Cervone (2003).
The crystal structure of polygalacturonase-inhibiting protein (PGIP), a leucine-rich repeat protein involved in plant defense.
  Proc Natl Acad Sci U S A, 100, 10124-10128.
PDB code: 1ogq
12962629 A.M.Larsson, R.Andersson, J.Ståhlberg, L.Kenne, and T.A.Jones (2003).
Dextranase from Penicillium minioluteum: reaction course, crystal structure, and product complex.
  Structure, 11, 1111-1121.
PDB codes: 1ogm 1ogo
14683403 M.Bachmann, and W.Janke (2003).
Multicanonical chain-growth algorithm.
  Phys Rev Lett, 91, 208105.  
12876365 M.Yamasaki, S.Moriwaki, W.Hashimoto, B.Mikami, and K.Murata (2003).
Crystallization and preliminary X-ray analysis of alginate lyase, a member of family PL-7, from Pseudomonas aeruginosa.
  Acta Crystallogr D Biol Crystallogr, 59, 1499-1501.  
12897238 N.Ferguson, J.Berriman, M.Petrovich, T.D.Sharpe, J.T.Finch, and A.R.Fersht (2003).
Rapid amyloid fiber formation from the fast-folding WW domain FBP28.
  Proc Natl Acad Sci U S A, 100, 9814-9819.  
12719262 O.N.Antzutkin, J.J.Balbach, and R.Tycko (2003).
Site-specific identification of non-beta-strand conformations in Alzheimer's beta-amyloid fibrils by solid-state NMR.
  Biophys J, 84, 3326-3335.  
12837775 P.R.Weigele, E.Scanlon, and J.King (2003).
Homotrimeric, beta-stranded viral adhesins and tail proteins.
  J Bacteriol, 185, 4022-4030.  
14635125 R.D'Avino, L.Camardella, T.M.Christensen, A.Giovane, and L.Servillo (2003).
Tomato pectin methylesterase: modeling, fluorescence, and inhibitor interaction studies-comparison with the bacterial (Erwinia chrysanthemi) enzyme.
  Proteins, 53, 830-839.  
12554946 T.Nakaniwa, T.Tada, K.Ishii, M.Takao, T.Sakai, and K.Nishimura (2003).
Crystallization and preliminary X-ray analysis of a thermostable pectate lyase PL 47 from Bacillus sp. TS 47.
  Acta Crystallogr D Biol Crystallogr, 59, 341-342.  
11967365 A.V.Kajava, and B.Kobe (2002).
Assessment of the ability to model proteins with leucine-rich repeats in light of the latest structural information.
  Protein Sci, 11, 1082-1090.  
12015145 E.K.Leinala, P.L.Davies, and Z.Jia (2002).
Crystal structure of beta-helical antifreeze protein points to a general ice binding model.
  Structure, 10, 619-627.
PDB code: 1l0s
12101406 H.J.Choi, S.Park-Snyder, L.T.Pascoe, K.J.Green, and W.I.Weis (2002).
Structures of two intermediate filament-binding fragments of desmoplakin reveal a unique repeat motif structure.
  Nat Struct Biol, 9, 612-620.
PDB codes: 1lm5 1lm7
11891310 H.Wille, M.D.Michelitsch, V.Guenebaut, S.Supattapone, A.Serban, F.E.Cohen, D.A.Agard, and S.B.Prusiner (2002).
Structural studies of the scrapie prion protein by electron crystallography.
  Proc Natl Acad Sci U S A, 99, 3563-3568.  
11910025 J.F.Kreisberg, S.D.Betts, C.Haase-Pettingell, and J.King (2002).
The interdigitated beta-helix domain of the P22 tailspike protein acts as a molecular clamp in trimer stabilization.
  Protein Sci, 11, 820-830.  
12124300 J.J.Balbach, A.T.Petkova, N.A.Oyler, O.N.Antzutkin, D.J.Gordon, S.C.Meredith, and R.Tycko (2002).
Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance.
  Biophys J, 83, 1205-1216.  
12015881 L.Cowen, P.Bradley, M.Menke, J.King, and B.Berger (2002).
Predicting the beta-helix fold from protein sequence data.
  J Comput Biol, 9, 261-276.  
12037303 L.M.Thomas, C.N.Doan, R.L.Oliver, and M.D.Yoder (2002).
Structure of pectate lyase A: comparison to other isoforms.
  Acta Crystallogr D Biol Crystallogr, 58, 1008-1015.
PDB codes: 1jrg 1jta
11914504 M.A.McDonough, C.Ryttersgaard, M.E.Bjørnvad, L.Lo Leggio, M.Schülein, S.O.Schrøder Glad, and S.Larsen (2002).
Crystallization and preliminary X-ray characterization of a thermostable pectate lyase from Thermotoga maritima.
  Acta Crystallogr D Biol Crystallogr, 58, 709-711.  
12410822 S.K.Ray, R.Rajeshwari, Y.Sharma, and R.V.Sonti (2002).
A high-molecular-weight outer membrane protein of Xanthomonas oryzae pv. oryzae exhibits similarity to non-fimbrial adhesins of animal pathogenic bacteria and is required for optimum virulence.
  Mol Microbiol, 46, 637-647.  
11929517 T.Palomäki, R.Pickersgill, R.Riekki, M.Romantschuk, and H.T.Saarilahti (2002).
A putative three-dimensional targeting motif of polygalacturonase (PehA), a protein secreted through the type II (GSP) pathway in Erwinia carotovora.
  Mol Microbiol, 43, 585-596.  
12022868 T.Shimizu, T.Nakatsu, K.Miyairi, T.Okuno, and H.Kato (2002).
Active-site architecture of endopolygalacturonase I from Stereum purpureum revealed by crystal structures in native and ligand-bound forms at atomic resolution.
  Biochemistry, 41, 6651-6659.
PDB codes: 1k5c 1kcc 1kcd
11703654 A.V.Kajava, N.Cheng, R.Cleaver, M.Kessel, M.N.Simon, E.Willery, F.Jacob-Dubuisson, C.Locht, and A.C.Steven (2001).
Beta-helix model for the filamentous haemagglutinin adhesin of Bordetella pertussis and related bacterial secretory proteins.
  Mol Microbiol, 42, 279-292.  
11504559 C.W.Ward, and T.P.Garrett (2001).
The relationship between the L1 and L2 domains of the insulin and epidermal growth factor receptors and leucine-rich repeat modules.
  BMC Bioinformatics, 2, 4.  
11432815 J.A.Vázquez-Boland, M.Kuhn, P.Berche, T.Chakraborty, G.Domínguez-Bernal, W.Goebel, B.González-Zorn, J.Wehland, and J.Kreft (2001).
Listeria pathogenesis and molecular virulence determinants.
  Clin Microbiol Rev, 14, 584-640.  
11687632 L.Federici, C.Caprari, B.Mattei, C.Savino, A.Di Matteo, G.De Lorenzo, F.Cervone, and D.Tsernoglou (2001).
Structural requirements of endopolygalacturonase for the interaction with PGIP (polygalacturonase-inhibiting protein).
  Proc Natl Acad Sci U S A, 98, 13425-13430.
PDB code: 1hg8
11717490 M.Akita, A.Suzuki, T.Kobayashi, S.Ito, and T.Yamane (2001).
The first structure of pectate lyase belonging to polysaccharide lyase family 3.
  Acta Crystallogr D Biol Crystallogr, 57, 1786-1792.
PDB code: 1ee6
11302165 M.Takao, T.Nakaniwa, K.Yoshikawa, T.Terashita, and T.Sakai (2001).
Molecular cloning, DNA sequence, and expression of the gene encoding for thermostable pectate lyase of thermophilic Bacillus sp. TS 47.
  Biosci Biotechnol Biochem, 65, 322-329.  
11752429 P.Bradley, L.Cowen, M.Menke, J.King, and B.Berger (2001).
BETAWRAP: successful prediction of parallel beta -helices from primary sequence reveals an association with many microbial pathogens.
  Proc Natl Acad Sci U S A, 98, 14819-14824.  
11468409 T.Shimizu, T.Nakatsu, K.Miyairi, T.Okuno, and H.Kato (2001).
Crystallization and preliminary X-ray study of endopolygalacturonase from the pathogenic fungus Stereum purpureum.
  Acta Crystallogr D Biol Crystallogr, 57, 1171-1173.  
11223531 T.Tada, C.T.Lu, Y.Nakamura, K.Wada, I.Miyahara, K.Hirotsu, Y.Katsuya, M.Sawada, M.Takao, T.Sakai, and K.Nishimura (2001).
Crystallization and preliminary X-ray analysis of a novel pectolytic enzyme, polymethoxygalacturonase SX1 from Trichosporon penicillatum.
  Acta Crystallogr D Biol Crystallogr, 57, 457-458.  
11157235 W.Hashimoto, H.Miki, N.Tsuchiya, H.Nankai, and K.Murata (2001).
Polysaccharide lyase: molecular cloning, sequencing, and overexpression of the xanthan lyase gene of Bacillus sp. strain GL1.
  Appl Environ Microbiol, 67, 713-720.  
11050437 B.Kobe, and A.V.Kajava (2000).
When protein folding is simplified to protein coiling: the continuum of solenoid protein structures.
  Trends Biochem Sci, 25, 509-515.  
10713524 C.N.Doan, M.K.Caughron, J.C.Myers, N.W.Breakfield, R.L.Oliver, and M.D.Yoder (2000).
Purification, crystallization and x-ray analysis of crystals of pectate lyase A from Exwinia chrysanthemi.
  Acta Crystallogr D Biol Crystallogr, 56, 351-353.  
11123920 D.E.Kamen, Y.Griko, and R.W.Woody (2000).
The stability, structural organization, and denaturation of pectate lyase C, a parallel beta-helix protein.
  Biochemistry, 39, 15932-15943.  
10872083 F.Laurent, A.Kotoujansky, and Y.Bertheau (2000).
Overproduction in Escherichia coli of the pectin methylesterase A from Erwinia chrysanthemi 3937: one-step purification, biochemical characterization, and production of polyclonal antibodies.
  Can J Microbiol, 46, 474-480.  
  11206055 J.F.Kreisberg, S.D.Betts, and J.King (2000).
Beta-helix core packing within the triple-stranded oligomerization domain of the P22 tailspike.
  Protein Sci, 9, 2338-2343.  
10899428 L.C.Serpell (2000).
Alzheimer's amyloid fibrils: structure and assembly.
  Biochim Biophys Acta, 1502, 16-30.  
10818352 M.Akita, A.Suzuki, T.Kobayashi, S.Ito, and T.Yamane (2000).
Crystallization and preliminary X-ray analysis of high-alkaline pectate lyase.
  Acta Crystallogr D Biol Crystallogr, 56, 749-750.
PDB code: 1ee6
10922035 M.Marino, L.Braun, P.Cossart, and P.Ghosh (2000).
A framework for interpreting the leucine-rich repeats of the Listeria internalins.
  Proc Natl Acad Sci U S A, 97, 8784-8788.  
11701835 N.T.Keen (2000).
A CENTURY OF PLANT PATHOLOGY: A Retrospective View on Understanding Host-Parasite Interactions.
  Annu Rev Phytopathol, 38, 31-48.  
10653812 R.Khurana, and A.L.Fink (2000).
Do parallel beta-helix proteins have a unique fourier transform infrared spectrum?
  Biophys J, 78, 994.  
  10716183 R.N.Jorissen, V.C.Epa, H.R.Treutlein, T.P.Garrett, C.W.Ward, and A.W.Burgess (2000).
Characterization of a comparative model of the extracellular domain of the epidermal growth factor receptor.
  Protein Sci, 9, 310-324.
PDB codes: 1dnq 1dnr
10922032 S.R.Herron, J.A.Benen, R.D.Scavetta, J.Visser, and F.Jurnak (2000).
Structure and function of pectic enzymes: virulence factors of plant pathogens.
  Proc Natl Acad Sci U S A, 97, 8762-8769.  
11018131 T.Y.Wong, L.A.Preston, and N.L.Schiller (2000).
ALGINATE LYASE: review of major sources and enzyme characteristics, structure-function analysis, biological roles, and applications.
  Annu Rev Microbiol, 54, 289-340.  
10930840 W.Huang, A.Matte, S.Suzuki, N.Sugiura, H.Miyazono, and M.Cygler (2000).
Crystallization and preliminary X-ray analysis of chondroitin sulfate ABC lyases I and II from Proteus vulgaris.
  Acta Crystallogr D Biol Crystallogr, 56, 904-906.  
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Modes of action of five different endopectate lyases from Erwinia chrysanthemi 3937.
  J Bacteriol, 181, 3705-3709.  
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Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing.
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Crystallization and preliminary X-ray diffraction study of the endo-polygalacturonase from Fusarium moniliforme.
  Acta Crystallogr D Biol Crystallogr, 55, 1359-1361.  
  10198006 M.A.Bekri, J.Desair, V.Keijers, P.Proost, M.Searle-van Leeuwen, J.Vanderleyden, and A.Vande Broek (1999).
Azospirillum irakense produces a novel type of pectate lyase.
  J Bacteriol, 181, 2440-2447.  
10408337 N.D.Lazo, and D.T.Downing (1999).
Fibril formation by amyloid-beta proteins may involve beta-helical protofibrils.
  J Pept Res, 53, 633-640.  
10089438 R.Pickersgill, M.Scott, D.Smith, K.Worboys, and J.Jenkins (1999).
Crystallization and preliminary crystallographic analysis of the endo-polygalacturonase from Erwinia carotovora ssp. carotovora.
  Acta Crystallogr D Biol Crystallogr, 55, 320-322.  
10404587 S.Betts, and J.King (1999).
There's a right way and a wrong way: in vivo and in vitro folding, misfolding and subunit assembly of the P22 tailspike.
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10052123 T.Kobayashi, K.Koike, T.Yoshimatsu, N.Higaki, A.Suzumatsu, T.Ozawa, Y.Hatada, and S.Ito (1999).
Purification and properties of a low-molecular-weight, high-alkaline pectate lyase from an alkaliphilic strain of Bacillus.
  Biosci Biotechnol Biochem, 63, 65-72.  
10216231 T.Kobayashi, Y.Hatada, N.Higaki, D.D.Lusterio, T.Ozawa, K.Koike, S.Kawai, and S.Ito (1999).
Enzymatic properties and deduced amino acid sequence of a high-alkaline pectate lyase from an alkaliphilic Bacillus isolate.
  Biochim Biophys Acta, 1427, 145-154.  
  10422829 W.R.Patterson, D.H.Anderson, W.F.DeGrado, D.Cascio, and D.Eisenberg (1999).
Centrosymmetric bilayers in the 0.75 A resolution structure of a designed alpha-helical peptide, D,L-Alpha-1.
  Protein Sci, 8, 1410-1422.
PDB code: 3al1
10216304 Y.Li, A.Matte, H.Su, and M.Cygler (1999).
Crystallization and preliminary X-ray analysis of chondroitinase B from Flavobacterium heparinum.
  Acta Crystallogr D Biol Crystallogr, 55, 1055-1057.  
  9655353 A.Bateman, A.G.Murzin, and S.A.Teichmann (1998).
Structure and distribution of pentapeptide repeats in bacteria.
  Protein Sci, 7, 1477-1480.  
9680962 C.Domingo, K.Roberts, N.J.Stacey, I.Connerton, F.Ruíz-Teran, and M.C.McCann (1998).
A pectate lyase from Zinnia elegans is auxin inducible.
  Plant J, 13, 17-28.  
  9537364 C.Finnie, A.Zorreguieta, N.M.Hartley, and J.A.Downie (1998).
Characterization of Rhizobium leguminosarum exopolysaccharide glycanases that are secreted via a type I exporter and have a novel heptapeptide repeat motif.
  J Bacteriol, 180, 1691-1699.  
  9686307 D.B.Teplow (1998).
Structural and kinetic features of amyloid beta-protein fibrillogenesis.
  Amyloid, 5, 121-142.  
  9515910 M.Lindeberg, C.M.Boyd, N.T.Keen, and A.Collmer (1998).
External loops at the C terminus of Erwinia chrysanthemi pectate lyase C are required for species-specific secretion through the out type II pathway.
  J Bacteriol, 180, 1431-1437.  
9492738 N.D.Lazo, and D.T.Downing (1998).
Amyloid fibrils may be assembled from beta-helical protofibrils.
  Biochemistry, 37, 1731-1735.  
9636063 S.Miller, B.Schuler, and R.Seckler (1998).
A reversibly unfolding fragment of P22 tailspike protein with native structure: the isolated beta-helix domain.
  Biochemistry, 37, 9160-9168.  
9761915 V.Shevchik, M.Scott, O.Mayans, and J.Jenkins (1998).
Crystallization and preliminary X-ray analysis of a member of a new family of pectate lyases, PeIL from Erwinia chrysanthemi.
  Acta Crystallogr D Biol Crystallogr, 54, 419-422.  
9187652 A.S.Robinson, and J.King (1997).
Disulphide-bonded intermediate on the folding and assembly pathway of a non-disulphide bonded protein.
  Nat Struct Biol, 4, 450-455.  
  8975898 E.Domann, S.Zechel, A.Lingnau, T.Hain, A.Darji, T.Nichterlein, J.Wehland, and T.Chakraborty (1997).
Identification and characterization of a novel PrfA-regulated gene in Listeria monocytogenes whose product, IrpA, is highly homologous to internalin proteins, which contain leucine-rich repeats.
  Infect Immun, 65, 101-109.  
  9098045 F.Tardy, W.Nasser, J.Robert-Baudouy, and N.Hugouvieux-Cotte-Pattat (1997).
Comparative analysis of the five major Erwinia chrysanthemi pectate lyases: enzyme characteristics and potential inhibitors.
  J Bacteriol, 179, 2503-2511.  
9204285 J.Heringa, and W.R.Taylor (1997).
Three-dimensional domain duplication, swapping and stealing.
  Curr Opin Struct Biol, 7, 416-421.  
9195887 O.Mayans, M.Scott, I.Connerton, T.Gravesen, J.Benen, J.Visser, R.Pickersgill, and J.Jenkins (1997).
Two crystal structures of pectin lyase A from Aspergillus reveal a pH driven conformational change and striking divergence in the substrate-binding clefts of pectin and pectate lyases.
  Structure, 5, 677-689.
PDB codes: 1idj 1idk
  9165091 S.Steinbacher, S.Miller, U.Baxa, A.Weintraub, and R.Seckler (1997).
Interaction of Salmonella phage P22 with its O-antigen receptor studied by X-ray crystallography.
  Biol Chem, 378, 337-343.  
9115442 T.N.Petersen, S.Kauppinen, and S.Larsen (1997).
The crystal structure of rhamnogalacturonase A from Aspergillus aculeatus: a right-handed parallel beta helix.
  Structure, 5, 533-544.
PDB code: 1rmg
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Pectate lyase PelI of Erwinia chrysanthemi 3937 belongs to a new family.
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8946845 B.Kobe (1996).
Leucines on a roll.
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  8665839 C.Kisker, H.Schindelin, B.E.Alber, J.G.Ferry, and D.C.Rees (1996).
A left-hand beta-helix revealed by the crystal structure of a carbonic anhydrase from the archaeon Methanosarcina thermophila.
  EMBO J, 15, 2323-2330.
PDB code: 1thj
  8566549 J.King, C.Haase-Pettingell, A.S.Robinson, M.Speed, and A.Mitraki (1996).
Thermolabile folding intermediates: inclusion body precursors and chaperonin substrates.
  FASEB J, 10, 57-66.  
8625428 S.Bartling, J.P.van den Hombergh, O.Olsen, D.von Wettstein, and J.Visser (1996).
Expression of an Erwinia pectate lyase in three species of Aspergillus.
  Curr Genet, 29, 474-481.  
8855221 S.Steinbacher, U.Baxa, S.Miller, A.Weintraub, R.Seckler, and R.Huber (1996).
Crystal structure of phage P22 tailspike protein complexed with Salmonella sp. O-antigen receptors.
  Proc Natl Acad Sci U S A, 93, 10584-10588.
PDB codes: 1tyu 1tyv 1tyw 1tyx
8535781 A.V.Kajava, G.Vassart, and S.J.Wodak (1995).
Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats.
  Structure, 3, 867-877.  
7583641 B.Kobe, and J.Deisenhofer (1995).
Proteins with leucine-rich repeats.
  Curr Opin Struct Biol, 5, 409-416.  
8592702 D.T.Downing (1995).
Molecular modeling indicates that homodimers form the basis for intermediate filament assembly from human and mouse epidermal keratins.
  Proteins, 23, 204-217.  
8577252 E.Lojkowska, C.Masclaux, M.Boccara, J.Robert-Baudouy, and N.Hugouvieux-Cotte-Pattat (1995).
Characterization of the pelL gene encoding a novel pectate lyase of Erwinia chrysanthemi 3937.
  Mol Microbiol, 16, 1183-1195.  
  7486993 F.Brühlmann (1995).
Purification and characterization of an extracellular pectate lyase from an Amycolata sp.
  Appl Environ Microbiol, 61, 3580-3585.  
7654407 I.W.Sutherland (1995).
Polysaccharide lyases.
  FEMS Microbiol Rev, 16, 323-347.  
  7613459 K.A.Dill, S.Bromberg, K.Yue, K.M.Fiebig, D.P.Yee, P.D.Thomas, and H.S.Chan (1995).
Principles of protein folding--a perspective from simple exact models.
  Protein Sci, 4, 561-602.  
7816806 K.Yue, and K.A.Dill (1995).
Forces of tertiary structural organization in globular proteins.
  Proc Natl Acad Sci U S A, 92, 146-150.  
7788717 M.C.Ho, M.P.Whitehead, T.E.Cleveland, and R.A.Dean (1995).
Sequence analysis of the Aspergillus nidulans pectate lyase pelA gene and evidence for binding of promoter regions to CREA, a regulator of carbon catabolite repression.
  Curr Genet, 27, 142-149.  
7583673 P.T.Lansbury, P.R.Costa, J.M.Griffiths, E.J.Simon, M.Auger, K.J.Halverson, D.A.Kocisko, Z.S.Hendsch, T.T.Ashburn, and R.G.Spencer (1995).
Structural model for the beta-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide.
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  8575190 S.Ernst, R.Langer, C.L.Cooney, and R.Sasisekharan (1995).
Enzymatic degradation of glycosaminoglycans.
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7476168 V.E.Shevchik, I.Bortoli-German, J.Robert-Baudouy, S.Robinet, F.Barras, and G.Condemine (1995).
Differential effect of dsbA and dsbC mutations on extracellular enzyme secretion in Erwinia chrysanthemi.
  Mol Microbiol, 16, 745-753.  
8539248 V.Sieber, F.Jurnak, and G.R.Moe (1995).
Circular dichroism of the parallel beta helical proteins pectate lyase C and E.
  Proteins, 23, 32-37.  
7817399 B.Kobe, and J.Deisenhofer (1994).
The leucine-rich repeat: a versatile binding motif.
  Trends Biochem Sci, 19, 415-421.  
  8069218 C.Daffner, G.Chelvanayagam, and P.Argos (1994).
Structural characteristics and stabilizing principles of bent beta-strands in protein tertiary architectures.
  Protein Sci, 3, 876-882.  
7712282 F.Jurnak, M.D.Yoder, R.Pickersgill, and J.Jenkins (1994).
Parallel beta-domains: a new fold in protein structures.
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8152378 I.Bortoli-German, E.Brun, B.Py, M.Chippaux, and F.Barras (1994).
Periplasmic disulphide bond formation is essential for cellulase secretion by the plant pathogen Erwinia chrysanthemi.
  Mol Microbiol, 11, 545-553.  
7922035 J.Janin (1994).
Proteins with a ring.
  Structure, 2, 571-573.  
  8143488 M.S.Johnson, N.Srinivasan, R.Sowdhamini, and T.L.Blundell (1994).
Knowledge-based protein modeling.
  Crit Rev Biochem Mol Biol, 29, 1.  
7634076 R.Pickersgill, J.Jenkins, G.Harris, W.Nasser, and J.Robert-Baudouy (1994).
The structure of Bacillus subtilis pectate lyase in complex with calcium.
  Nat Struct Biol, 1, 717-723.
PDB code: 1bn8
  8168497 V.E.Shevchik, G.Condemine, and J.Robert-Baudouy (1994).
Characterization of DsbC, a periplasmic protein of Erwinia chrysanthemi and Escherichia coli with disulfide isomerase activity.
  EMBO J, 13, 2007-2012.  
  8074530 Y.Liu, A.Chatterjee, and A.K.Chatterjee (1994).
Nucleotide sequence and expression of a novel pectate lyase gene (pel-3) and a closely linked endopolygalacturonase gene (peh-1) of Erwinia carotovora subsp. carotovora 71.
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8081735 C.Chothia, and A.G.Murzin (1993).
New folds for all-beta proteins.
  Structure, 1, 217-222.  
8081738 M.D.Yoder, S.E.Lietzke, and F.Jurnak (1993).
Unusual structural features in the parallel beta-helix in pectate lyases.
  Structure, 1, 241-251.
PDB code: 1pcl
8236448 S.R.Sprang (1993).
On a (beta-) roll.
  Trends Biochem Sci, 18, 313-314.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.

 

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