7bz5

X-ray diffraction
1.84Å resolution

Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike protein S1 Chain: A
Molecule details ›
Chain: A
Length: 229 amino acids
Theoretical weight: 25.95 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P0DTC2 (Residues: 319-541; Coverage: 18%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Heavy chain of B38 Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 23.44 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Light chain of B38 Chain: L
Molecule details ›
Chain: L
Length: 218 amino acids
Theoretical weight: 23.75 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: C2
Unit cell:
a: 195.226Å b: 86.417Å c: 56.827Å
α: 90° β: 100.19° γ: 90°
R-values:
R R work R free
0.168 0.167 0.191
Expression systems:
  • Spodoptera frugiperda
  • Homo sapiens