› 7t91

X-ray diffraction
2.05Å resolution

Crystal structure of Zinc finger motif 1 and 2 of GLI1 DNA binding region

Released:
DOI: 10.2210/pdb7t91/pdb
PDB entry 7t91 coloured by chain, front view.
PDB entry 7t91 coloured by chain, side view.
PDB entry 7t91 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wu M, Zhang S, Augelli-Szanfran CE, Boohaker RJ

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139937 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger protein GLI1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 71 amino acids
Theoretical weight: 8.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P08151 (Residues: 234-302; Coverage: 6%)
Gene names: GLI, GLI1

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P65
Unit cell:
a: 66.728Å b: 66.728Å c: 65.909Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.194 0.192 0.236
Expression system: Escherichia coli

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