› › Structure analysis

cryo-em structure of alpha-synuclein fibril polymorph 2B

Electron Microscopy
3.4Å resolution
PDB entry 6sst coloured by chain, front view.
PDB entry 6sst coloured by chain, side view.
PDB entry 6sst coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo decamer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Alpha-synuclein
hide full assembly name
Multimeric state: homo decamer
Accessible surface area: 25923.33 Å2
Buried surface area: 44297.02 Å2
Dissociation area: 557.1 Å2
Dissociation energy (ΔGdiss): -12.34 kcal/mol
Dissociation entropy (TΔSdiss): 12.86 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-153502

Macromolecules

Alpha-synuclein
Chains: A, B, C, D, E, F, G, H, I, J
Length: 140 amino acids
Theoretical weight: 14.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P37840 (Residues: 1-140; Coverage: 100%)
Gene names: NACP, PARK1, SNCA
Pfam: Synuclein
InterPro:
Alpha-synuclein in PDB entry 6sst, assembly 1, front view.
Alpha-synuclein in PDB entry 6sst, assembly 1, side view.
Alpha-synuclein in PDB entry 6sst, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links