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Human parainfluenza virus type 3 fusion protein N-terminal heptad repeat domain+VIQKI

X-ray diffraction
1.75Å resolution
PDB entry 6nro coloured by chain, front view.
PDB entry 6nro coloured by chain, side view.
PDB entry 6nro coloured by chain, top view.
Source organism: Human respirovirus 3
Assembly composition:
hetero hexamer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Fusion glycoprotein F0
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Multimeric state: hetero hexamer
Accessible surface area: 10711.83 Å2
Buried surface area: 13824.13 Å2
Dissociation area: 4,122.58 Å2
Dissociation energy (ΔGdiss): 69.14 kcal/mol
Dissociation entropy (TΔSdiss): 23.85 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-139249

Macromolecules

Fusion glycoprotein F1
Chains: A, C, E
Length: 53 amino acids
Theoretical weight: 5.66 KDa
Source organism: Human respirovirus 3
Expression system: Not provided
UniProt:
  • Canonical: P06828 (Residues: 139-189; Coverage: 10%)
Gene name: F
InterPro: Precursor fusion glycoprotein F0, Paramyxoviridae
Fusion glycoprotein F1 in PDB entry 6nro, assembly 1, front view.
Fusion glycoprotein F1 in PDB entry 6nro, assembly 1, side view.
Fusion glycoprotein F1 in PDB entry 6nro, assembly 1, top view.
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Fusion glycoprotein F1
Chains: B, D, F
Length: 38 amino acids
Theoretical weight: 4.19 KDa
Source organism: Human respirovirus 3
Expression system: Not provided
UniProt:
  • Canonical: P06828 (Residues: 449-484; Coverage: 7%)
Gene name: F
Fusion glycoprotein F1 in PDB entry 6nro, assembly 1, front view.
Fusion glycoprotein F1 in PDB entry 6nro, assembly 1, side view.
Fusion glycoprotein F1 in PDB entry 6nro, assembly 1, top view.
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