Function and Biology

Structure of human 4-1BB / 4-1BBL complex

Source organism: Homo sapiens
Biochemical function: tumor necrosis factor receptor superfamily binding
Biological process: immune response
Cellular component: membrane

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00020
Domain description: TNFR/NGFR cysteine-rich region
Occurring in:
  1. Tumor necrosis factor receptor superfamily member 9
The deposited structure of PDB entry 6mgp contains 3 copies of Pfam domain PF00020 (TNFR/NGFR cysteine-rich region) in Tumor necrosis factor receptor superfamily member 9. Showing 1 copy in chain D [auth X].

PF00229
Domain description: TNF(Tumour Necrosis Factor) family
Occurring in:
  1. Tumor necrosis factor ligand superfamily member 9
The deposited structure of PDB entry 6mgp contains 3 copies of Pfam domain PF00229 (TNF(Tumour Necrosis Factor) family ) in Tumor necrosis factor ligand superfamily member 9. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR006052
Domain description: Tumour necrosis factor domain
Occurring in:
  1. Tumor necrosis factor ligand superfamily member 9
IPR001368
Domain description: TNFR/NGFR cysteine-rich region
Occurring in:
  1. Tumor necrosis factor receptor superfamily member 9
IPR008983
Domain description: Tumour necrosis factor-like domain superfamily
Occurring in:
  1. Tumor necrosis factor ligand superfamily member 9
IPR034020
Domain description: Tumour necrosis factor receptor 9, N-terminal
Occurring in:
  1. Tumor necrosis factor receptor superfamily member 9
IPR021184
Domain description: Tumour necrosis factor, conserved site
Occurring in:
  1. Tumor necrosis factor ligand superfamily member 9
IPR042373
Domain description: Tumor necrosis factor ligand superfamily member 9
Occurring in:
  1. Tumor necrosis factor ligand superfamily member 9

Structure domain

CATH CATH domain
2.60.120.40
Class: Mainly Beta
Architecture: Sandwich
Topology: Jelly Rolls
Homology: Jelly Rolls
Occurring in:
  1. Tumor necrosis factor ligand superfamily member 9
The deposited structure of PDB entry 6mgp contains 3 copies of CATH domain 2.60.120.40 (Jelly Rolls) in Tumor necrosis factor ligand superfamily member 9. Showing 1 copy in chain B.