Function and Biology Details
Reactions catalysed:
ATP + RNA(n) = diphosphate + RNA(n+1)
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126284 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Terminal nucleotidyltransferase 5C
Molecule details ›
Chain: A
Length: 345 amino acids
Theoretical weight: 39.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Nucleotidyltransferase
Length: 345 amino acids
Theoretical weight: 39.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q5VWP2 (Residues: 14-358; Coverage: 88%)
Sequence domains: Nucleotidyltransferase
Serine/threonine-protein kinase PLK4
Molecule details ›
Chain: B
Length: 223 amino acids
Theoretical weight: 25.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 223 amino acids
Theoretical weight: 25.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O00444 (Residues: 585-807; Coverage: 23%)
Sequence domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID
Spacegroup:
P3121
Expression system: Escherichia coli
