› 5zy6

X-ray diffraction
2.1Å resolution

catechol methyltransferase spCOMT

Released:
DOI: 10.2210/pdb5zy6/pdb
PDB entry 5zy6 coloured by chain, front view.
PDB entry 5zy6 coloured by chain, side view.
PDB entry 5zy6 coloured by chain, top view.
Source organism: Schizosaccharomyces pombe 972h-
Entry authors: Wang Q, Xu L

Function and Biology Details

Reaction catalysed: 
S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128818 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable catechol O-methyltransferase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 274 amino acids
Theoretical weight: 31.41 KDa
Source organism: Schizosaccharomyces pombe 972h-
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: O42898 (Residues: 1-266; Coverage: 100%)
Gene name: SPBC119.03
Sequence domains: O-methyltransferase

Ligands and Environments


Cofactor: Ligand SAM 2 x SAM
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P212121
Unit cell:
a: 71.265Å b: 78.858Å c: 102.781Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.185 0.234
Expression system: Escherichia coli K-12

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