› 5yxn

X-ray diffraction
2.03Å resolution

A T cell receptor in complex with HLA-A0201 restricted Hepatitis C virus NS3 peptide (KLVALGINAV)

Released:
DOI: 10.2210/pdb5yxn/pdb
PDB entry 5yxn coloured by chain, front view.
PDB entry 5yxn coloured by chain, side view.
PDB entry 5yxn coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Hui F

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-209022 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
T cell receptor alpha chain Chain: A
Molecule details ›
Chain: A
Length: 192 amino acids
Theoretical weight: 21.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
T cell receptor beta chain Chain: B
Molecule details ›
Chain: B
Length: 241 amino acids
Theoretical weight: 27.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
HLA class I histocompatibility antigen, A alpha chain Chain: C
Molecule details ›
Chain: C
Length: 275 amino acids
Theoretical weight: 31.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P04439 (Residues: 25-299)
Gene names: HLA-A, HLAA
Beta-2-microglobulin Chain: D
Molecule details ›
Chain: D
Length: 100 amino acids
Theoretical weight: 11.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P61769 (Residues: 20-119)
Gene names: B2M, CDABP0092, HDCMA22P
Serine protease/helicase NS3 Chain: I
Molecule details ›
Chain: I
Length: 10 amino acids
Theoretical weight: 998 Da
UniProt:
  • Best match: P27958 (Residues: 1406-1415)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Unit cell:
a: 79.99Å b: 53.65Å c: 224.981Å
α: 90° β: 95.27° γ: 90°
R-values:
R R work R free
0.194 0.193 0.223
Expression system: Escherichia coli

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