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Abl2 SH3

X-ray diffraction
2Å resolution
PDB entry 5np3 coloured by chain, front view.
PDB entry 5np3 coloured by chain, side view.
PDB entry 5np3 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Tyrosine-protein kinase ABL2
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Multimeric state: monomeric
Accessible surface area: 3605.92 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-154850
Assembly 2
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Assembly Name: Tyrosine-protein kinase ABL2
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Multimeric state: monomeric
Accessible surface area: 3803.11 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-154850
Assembly 3
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Assembly Name: Tyrosine-protein kinase ABL2
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Multimeric state: monomeric
Accessible surface area: 3722.08 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-154850
Assembly 4
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Assembly Name: Tyrosine-protein kinase ABL2
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Multimeric state: monomeric
Accessible surface area: 3902.06 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-154850

Macromolecules

Tyrosine-protein kinase ABL2
Chains: A, B, C, D
Length: 61 amino acids
Theoretical weight: 6.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P42684 (Residues: 110-166; Coverage: 5%)
Gene names: ABL2, ABLL, ARG
Pfam: SH3 domain
InterPro:
CATH: SH3 Domains
Tyrosine-protein kinase ABL2 in PDB entry 5np3, assembly 1, front view.
Tyrosine-protein kinase ABL2 in PDB entry 5np3, assembly 1, side view.
Tyrosine-protein kinase ABL2 in PDB entry 5np3, assembly 1, top view.
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