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Structure of C. elegans PCH-2

X-ray diffraction
2.301Å resolution
PDB entry 4xgu coloured by chain, front view.
PDB entry 4xgu coloured by chain, side view.
PDB entry 4xgu coloured by chain, top view.
Source organism: Caenorhabditis elegans
Assemblies composition:
homo hexamer (preferred)
homo dodecamer
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Putative pachytene checkpoint protein 2
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Multimeric state: homo hexamer
Accessible surface area: 102721.83 Å2
Buried surface area: 17324.62 Å2
Dissociation area: 4,435.82 Å2
Dissociation energy (ΔGdiss): 5.66 kcal/mol
Dissociation entropy (TΔSdiss): 45.83 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-170812
Assembly 2
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Assembly Name: Putative pachytene checkpoint protein 2
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Multimeric state: homo dodecamer
Accessible surface area: 203858.74 Å2
Buried surface area: 36234.16 Å2
Dissociation area: 9,664.09 Å2
Dissociation energy (ΔGdiss): 1.33 kcal/mol
Dissociation entropy (TΔSdiss): 109.42 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-170811

Macromolecules

Putative pachytene checkpoint protein 2
Chains: A, B, C, D, E, F
Length: 424 amino acids
Theoretical weight: 48.08 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: Q09535 (Residues: 1-424; Coverage: 100%)
Gene names: F10B5.5, pch-2
Pfam: ATPase family associated with various cellular activities (AAA)
InterPro:
Putative pachytene checkpoint protein 2 in PDB entry 4xgu, assembly 1, front view.
Putative pachytene checkpoint protein 2 in PDB entry 4xgu, assembly 1, side view.
Putative pachytene checkpoint protein 2 in PDB entry 4xgu, assembly 1, top view.
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