› 4r6i

X-ray diffraction
2.65Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Anthrax toxin expression trans-acting positive regulator Chains: A, B
Molecule details ›
Chains: A, B
Length: 478 amino acids
Theoretical weight: 56.33 KDa
Source organism: Bacillus anthracis str. 'Ames Ancestor'
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q44636 (Residues: 1-475; Coverage: 100%)
Gene names: BXA0146, GBAA_pXO1_0146, atxA, pXO1-119
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand LMT 2 x LMT
1 modified residue:
Ligand MSE 18 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I222
Unit cell:
a: 130.46Å b: 135.167Å c: 180.908Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.196 0.252
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Regulatory gene mutation: a driving force behind group a Streptococcus strain- and serotype-specific variation.
Sarkar et al. (2017)
1 more

4 mentions without citation

PRD-Containing Virulence Regulators (PCVRs) in Pathogenic Bacteria.
Rom et al. (2021)
3 more