› 4q12

X-ray diffraction
2.85Å resolution

Crystal structure of a putative uncharacterized protein Rv3404c and likely sugar N-formyltransferase from Mycobacterium tuberculosis bound to uridine diphosphate

Released:
DOI: 10.2210/pdb4q12/pdb
PDB entry 4q12 coloured by chain, front view.
PDB entry 4q12 coloured by chain, side view.
PDB entry 4q12 coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Entry authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161765 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
dTDP-4-amino-4,6-dideoxyglucose formyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 256 amino acids
Theoretical weight: 28.94 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WKZ3 (Residues: 2-234; Coverage: 100%)
Gene names: MTCY78.24, Rv3404c
Sequence domains:
Structure domains: Formyl transferase, N-terminal domain

Ligands and Environments

3 bound ligands:
Ligand UDP 2 x UDP
Ligand EDO 8 x EDO
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: I4132
Unit cell:
a: 271.94Å b: 271.94Å c: 271.94Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.172 0.172 0.194
Expression system: Escherichia coli

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