› 4jc8

X-ray diffraction
2.6Å resolution

Crystal Structure of HOPS component Vps33 from Chaetomium thermophilum

Released:
DOI: 10.2210/pdb4jc8/pdb
PDB 4jc8 coloured by chain and viewed from the front.
PDB 4jc8 coloured by chain and viewed from the side.
PDB 4jc8 coloured by chain and viewed from the top.
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Primary publication:
Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*
Baker RW, Jeffrey PD, Hughson FM
PLoS ONE 8 e67409 (2013)
PMID: 23840694

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UBC core domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 669 amino acids
Theoretical weight: 74.37 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: G0SCM5 (Residues: 139-806; Coverage: 83%)
Gene name: CTHT_0057760
Sequence domains: Sec1 family
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P21
Unit cell:
a: 71.936Å b: 64.436Å c: 151.685Å
α: 90° β: 91.77° γ: 90°
R-values:
R R work R free
0.188 0.185 0.247
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

10 review citations

Chaperoning SNARE Folding and Assembly.
Zhang et al. (2021)
9 more

1 mention without citation

Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*.
Baker et al. (2013)