› 4izh

X-ray diffraction
1.8Å resolution

Crystal Structure of the Alpha1 dimer of Thermus thermophilus Transhydrogenase in P6

Released:
DOI: 10.2210/pdb4izh/pdb
PDB entry 4izh coloured by chain, front view.
PDB entry 4izh coloured by chain, side view.
PDB entry 4izh coloured by chain, top view.
Source organism: Thermus thermophilus HB27
Entry authors: Stout CD, Yamaguchi M, Leung J

Function and Biology Details

Reaction catalysed: 
NADPH + NAD(+) + H(+)(Side 1) = NADP(+) + H(+)(Side 2) + NADH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180812 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
proton-translocating NAD(P)(+) transhydrogenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 381 amino acids
Theoretical weight: 40.85 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q72GR8 (Residues: 1-375; Coverage: 100%)
Gene name: TT_C1780
Sequence domains:
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

1 bound ligand:
Ligand GOL 13 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P6
Unit cell:
a: 162.318Å b: 162.318Å c: 73.883Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.167 0.18
Expression system: Escherichia coli BL21(DE3)

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