EC 1.3.8.1: Short-chain acyl-CoA dehydrogenase
Reaction catalysed:
A short-chain acyl-CoA + electron-transfer flavoprotein = a short-chain trans-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein
Systematic name:
Short-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Alternative Name(s):
- 3-hydroxyacyl CoA reductase
- ACADS (gene name)
- Butanoyl-CoA dehydrogenase
- Butanoyl-CoA:(acceptor) 2,3-oxidoreductase
- Butyryl coenzyme A dehydrogenase
- Butyryl dehydrogenase
- Butyryl-CoA dehydrogenase
- Enoyl-coenzyme A reductase
- Ethylene reductase
- Short-chain acyl CoA dehydrogenase
- Short-chain acyl-coenzyme A dehydrogenase
- Unsaturated acyl coenzyme A reductase
- Unsaturated acyl-CoA reductase
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence families
Protein families (Pfam)
InterPro annotations
IPR046373
Domain description:
Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
Occurring in:
Occurring in:
IPR009100
Domain description:
Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
Occurring in:
Occurring in:
Structure domains
CATH domains
1.20.140.10
Class:
Mainly Alpha
Architecture:
Up-down Bundle
Topology:
Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homology:
Butyryl-CoA Dehydrogenase, subunit A, domain 3
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4iv6</span> contains 2 copies of CATH domain <span class='highlight'>1.20.140.10 (Butyryl-CoA Dehydrogenase, subunit A; domain 3)</span> in <span class='highlight'>Isovaleryl-CoA dehydrogenase</span>. Showing 1 copy in chain <span class='highlight'>B</span>. The deposited structure of PDB entry 4iv6 contains 2 copies of CATH domain 1.20.140.10 (Butyryl-CoA Dehydrogenase, subunit A; domain 3) in Isovaleryl-CoA dehydrogenase. Showing 1 copy in chain B.](https://www.ebi.ac.uk/pdbe/static/entry/4iv6_1_B_CATH_1.20.140.10_image-200x200.png)
2.40.110.10
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
Butyryl-CoA Dehydrogenase, subunit A; domain 2
Homology:
Butyryl-CoA Dehydrogenase, subunit A, domain 2
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>4iv6</span> contains 2 copies of CATH domain <span class='highlight'>2.40.110.10 (Butyryl-CoA Dehydrogenase, subunit A; domain 2)</span> in <span class='highlight'>Isovaleryl-CoA dehydrogenase</span>. Showing 1 copy in chain <span class='highlight'>B</span>. The deposited structure of PDB entry 4iv6 contains 2 copies of CATH domain 2.40.110.10 (Butyryl-CoA Dehydrogenase, subunit A; domain 2) in Isovaleryl-CoA dehydrogenase. Showing 1 copy in chain B.](https://www.ebi.ac.uk/pdbe/static/entry/4iv6_1_B_CATH_2.40.110.10_image-200x200.png)