Function and Biology Details
Reactions catalysed:
L-gulonate + NADP(+) = D-glucuronate + NADPH
An alcohol + NADP(+) = an aldehyde + NADPH
L-gulono-1,4-lactone + NADP(+) = D-glucurono-3,6-lactone + NADPH
Glycerol + NADP(+) = D-glyceraldehyde + NADPH
Allyl alcohol + NADP(+) = acrolein + NADPH
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Aldo-keto reductase family 1 member A1 (preferred)
PDBe Complex ID:
PDB-CPX-191606 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldo-keto reductase family 1 member A1
Molecule details ›
Chains: A, B
Length: 324 amino acids
Theoretical weight: 36.51 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Aldo/keto reductase family
Structure domains: NADP-dependent oxidoreductase domain
Length: 324 amino acids
Theoretical weight: 36.51 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9JII6 (Residues: 2-325; Coverage: 100%)
Sequence domains: Aldo/keto reductase family
Structure domains: NADP-dependent oxidoreductase domain
