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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH BENZYL-HYDANTOIN

X-ray diffraction
3.8Å resolution
PDB entry 4d1b coloured by chain, front view.
PDB entry 4d1b coloured by chain, side view.
PDB entry 4d1b coloured by chain, top view.
Source organism: Microbacterium liquefaciens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Hydantoin permease
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Multimeric state: monomeric
Accessible surface area: 17744.79 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-112805

Macromolecules

Hydantoin permease
Chain: A
Length: 495 amino acids
Theoretical weight: 54.02 KDa
Source organism: Microbacterium liquefaciens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D6R8X8 (Residues: 1-487; Coverage: 100%)
Gene name: hyuP
Pfam: Permease for cytosine/purines, uracil, thiamine, allantoin
InterPro:
CATH: Hydantoin permease
Hydantoin permease in PDB entry 4d1b, assembly 1, front view.
Hydantoin permease in PDB entry 4d1b, assembly 1, side view.
Hydantoin permease in PDB entry 4d1b, assembly 1, top view.
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