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Human PDK1-PKCzeta Kinase Chimera

X-ray diffraction
1.25Å resolution
PDB entry 4ct2 coloured by chain, front view.
PDB entry 4ct2 coloured by chain, side view.
PDB entry 4ct2 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: 3-phosphoinositide-dependent protein kinase 1
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Multimeric state: monomeric
Accessible surface area: 12872.6 Å2
Buried surface area: 1275.48 Å2
Dissociation area: 147.39 Å2
Dissociation energy (ΔGdiss): -0.86 kcal/mol
Dissociation entropy (TΔSdiss): 2.15 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-127511

Macromolecules

3-phosphoinositide-dependent protein kinase 1
Chain: A
Length: 311 amino acids
Theoretical weight: 35.37 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Best match: O15530 (Residues: 50-359)
Gene names: PDK1, PDPK1
3-phosphoinositide-dependent protein kinase 1 in PDB entry 4ct2, assembly 1, front view.
3-phosphoinositide-dependent protein kinase 1 in PDB entry 4ct2, assembly 1, side view.
3-phosphoinositide-dependent protein kinase 1 in PDB entry 4ct2, assembly 1, top view.
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