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Structure of the apo MET receptor kinase in the dually-phosphorylated, activated state

X-ray diffraction
1.6Å resolution
PDB entry 3q6u coloured by chain, front view.
PDB entry 3q6u coloured by chain, side view.
PDB entry 3q6u coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Hepatocyte growth factor receptor
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-140186

Macromolecules

Hepatocyte growth factor receptor
Chain: A
Length: 308 amino acids
Theoretical weight: 35.13 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Best match: P08581 (Residues: 1048-1348)
Gene name: MET
Hepatocyte growth factor receptor in PDB entry 3q6u, assembly 1, front view.
Hepatocyte growth factor receptor in PDB entry 3q6u, assembly 1, side view.
Hepatocyte growth factor receptor in PDB entry 3q6u, assembly 1, top view.
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